Leticia Martín-Cruz

PhD | Immunology | Biochemistry
@unicomplutense

[ApS Enfermedades y Cine UCM @ApsUcm]

🎬 ¿Estudias Biología, Farmacia, Medicina o Veterinaria en la @UCM?
¡Participa en el ApS "Cine en compañía para prevenir enfermedades"! 🍿🩺
🔹 Aprende salud y apoya a colectivos vulnerables.
🗓️ Hasta el 15 de octubre
📩 [email protected] | [email protected]
¡Plazas limitadas!

[Oscar Palomares' Lab @Palomares_Lab]

Tezepelumab Reverses TSLP-Driven Immunometabolic Rewiring in Human cDC2s https://t.co/dT2LAr52HD a través de @YouTube

[Oscar Palomares' Lab @Palomares_Lab]

Palomares' Lab at SEI2026 in Córdoba!! Alba Angelina ("Peanut allergoid-mannan conjugates for food allergy IT"), Leticia Martín ("Tumoral Ca10 and Tregs), Natalia Cuervo ("Cannabinoids in keratinocytes"), Isabel Peñalver ("TSLP-induced metabolic rewiring in cDC2s"). Well done!!

[Oscar Palomares' Lab @Palomares_Lab]

Palomares’ Lab members at an exciting meeting on the challenges and opportunities in immunology to fight antimicrobial resistance at Hospital Clínico San Carlos. Congratulations to the organizers and all the speakers for the excellent talks and discussions! Truly enjoyable!

[A golpe de bit @agolpedebit]

💉En @inmunotek se está investigando la vacuna MV130, una vacuna para prevenir el desarrollo del asma.

🗣️Nos lo cuentan @Palomares_Lab investigador en @unicomplutense y Laura Conejero, investigadora en inmunología.

🔗 A las 10.30 horas en
@ree_rne
https://t.co/aAvN2uQku8

[SINC @agencia_sinc]

La vacuna MV130, desarrollada por la empresa española @inmunotek y probado en la @unicomplutense, ha mostrado un efecto protector frente al asma alérgica eosinofílica en ratones y en modelos preclínicos humanos.

https://t.co/a3r4qrqnwD

[Oscar Palomares' Lab @Palomares_Lab]

Muy contentos de que nuestros hallazgos con la vacuna bacteriana MV130 de Inmunotek pueda mejorar la vida de los pacientes asmáticos! Seguimos trabajando para ello!! https://t.co/vY0m9BJYEC

[Oscar Palomares' Lab @Palomares_Lab]

Muy contentos de que nuestros hallazgos con la vacuna bacteriana MV130 de Inmunotek pueda mejorar la vida de los pacientes asmáticos! Seguimos trabajando para ello!! https://t.co/meTFZpA59V

[Complutense @unicomplutense]

Una #vacuna española abre una nueva vía en la prevención del #asma

La investigación dirigida por @Palomares_Lab en colaboración con Laura Conejero y José Luis Subiza (@inmunotek), demuestra por primera vez que la #vacunaMV130 previene el desarrollo de asma alérgica eosinofílica en modelos animales, con un efecto protector que se mantiene hasta nueve semanas después de finalizar el tratamiento.
@ucc_complutense

[Oscar Palomares' Lab @Palomares_Lab]

Happy to share our last findings published in @NatureComms: https://t.co/1IOJuEkpYw
showing that MV130, a polybacterial mucosal vaccine, prevents allergic eosinophilic asthma development, conferring protection up to 9 weeks after vaccination by regulating DCs functional features

[Oscar Palomares' Lab @Palomares_Lab]

A great honor to recieve the AeDA Immunotherapy Award 2025 and give a talk in the plenary session in Allergologie im Kloster 2025 congress. This is dedicated to all members of the "Vaccines and Dendritic Cells Lab" at UCM and to all our collaborators & friends during these years!

[Oscar Palomares' Lab @Palomares_Lab]

Happy to share our last findings published in @jacionline in collaboration with @SIAF_UZH. We keep working on cannabinoids & epithelial cells!
Cannabinoid WIN55,212-2 restores bronchial epithelium by regulating oxidative stress and STAT6 phosphorylation https://t.co/ofUC2i99lt

[EAACI JM @EAACI_JM]

Can trained immunity revolutionise allergen immunotherapy? A new review explores how metabolic & epigenetic rewiring of immune cells enhance tolerance and reshape allergy treatment.
Could this be the next step in allergy vaccines? @AllergyEaaci
Read more: https://t.co/RKHZhh5W3e

[Oscar Palomares' Lab @Palomares_Lab]

Congratulations to our new Doctor Mario Pérez Diego for his excellent Thesis on the role of cannabinoids in the regulation of myeloid and bronchial epithelial cells in asthma and other inflammatory diseases. Thank you to the outstanding Comiittee for great discussions and inputs!

[Allergy EAACI @AllergyEaaci]

The Role of IgE in Crohn's Disease by Impairing the Capacity of Plasmacytoid Dendritic Cells to Generate FOXP3+ Tregs. First author: Andrés de la Rocha-Muñoz; corresponding author : Oscar Palomares

Read the article here: https://t.co/RguIY2ntQ2

This study uncovers an unprecedented role for IgE in Crohn’s disease (CD). CD patients, regardless of allergic status and similar to allergic patients, display higher levels of circulating IgE+ and FcεRI+ immune cells, including plasmacytoid dendritic cells (pDCs), which are concomitant to fewer Tregs. In vitro experiments show that the anti-IgE monoclonal antibody #omalizumab restores the ability of pDCs from CD patients to generate Tregs.

Read more articles published in #Allergy on gastrointestinal disease here: Original Articles: Food Allergy and Gastrointestinal Diseases - Allergy

#Allergy_journal @Palomares_Lab

[Oscar Palomares' Lab @Palomares_Lab]

Palomares Lab members presinting last unpublished data in outstanding WIRM 2025 in Davos !. Oscar Palomares (Role of cannabinoids in allergy), Alba Angelina (Allergoids conjugated to mannan as novel vaccines for peanut allergy) and Leticia Martín-Cruz (Regulation of TSLP in DCs).

[Oscar Palomares' Lab @Palomares_Lab]

Cristina Benito-Villalvilla presents our recent published data in Allergy about The role of IgE in Crohn's disease https://t.co/iWy1VmENQd a través de @YouTube. Congratulations to all coauthors for their outstanding contributions!

[Oscar Palomares' Lab @Palomares_Lab]

Congratulations to Ana Carmen Sevilla for her excellent Thesis on MV130 bacterial vaccine for the prevention and treatment of asthma in collaboration with Inmunotek: "Doctorado Industrial" programm funded by CAM. Thank you to the oustanding Committee for great discussions!

[Allergy EAACI @AllergyEaaci]

Open Access: Allergen-Specific Immunotherapy and Trained Immunity. Leticia Martín-Cruz, Oscar Palomares

Read the article here: https://t.co/5x2kT5okAh

With over 110 references and 5 figures, this comprehensive review article summarizes our current knowledge of the molecular mechanisms involved in allergen-specific #immunotherapy (AIT) for the treatment of allergies. It includes a discussion on the immunological mechanisms underlying successful AIT; trained immunity: novel findings and applications in vaccinology; allergic diseases and trained immunity; toward novel trained immunity-based allergen vaccines; conclusions and future perspectives.

#Allergy_journal @Palomares_Lab
Read more articles published in #Allergy on allergen-specific immunotherapy here: Original Articles: Allergen-Specific Immunotherapy and Biologics - Allergy

[Oscar Palomares' Lab @Palomares_Lab]

Dear friends and collaborators the Vaccines & Dendritic Cells Lab wish you all Merry Christmas and a Happy New Year 2025 plenty of health, great moments and success!!