Liam

working for psychedelics and mental health companies

[Liam @liamcubed]

still very sleep deprived and have tons of work to do which sucks. I’m feeling weirdly chill about it though

[Liam @liamcubed]

nervous system feeling regulated af post-vibecamp

[kasra @kasratweets]

bringing back the best pieces of media on this

[𝙼𝚘𝙼Ⓐ𝖕𝖘𝖋𝖎𝖛𝖊™ @interracials3x]

clubbing and raving is such an ancient thing it's so cool how we have all this technology and modernity yet we still gather large crowds in rooms to dance to music on substances for hours on end even hunter gatherers did this shit it's deep

[Liam @liamcubed]

@orphcorp orph orph orph please add me to the groupchat you had mentioned a couple hours ago! if that’s still a thing

[Liam @liamcubed]

this essay changed me why hasn’t it gone mega viral yet

[Daniel Thorson @dthorson]

https://t.co/zdepY0c1BF

[Aakash Gupta @aakashgupta]

The math on this project should mass-humble every AI lab on the planet.

1 cubic millimeter. One-millionth of a human brain. Harvard and Google spent 10 years mapping it. The imaging alone took 326 days. They sliced the tissue into 5,000 wafers each 30 nanometers thick, ran them through a $6 million electron microscope, then needed Google’s ML models to stitch the 3D reconstruction because no human team could process the output.

The result: 57,000 cells, 150 million synapses, 230 millimeters of blood vessels, compressed into 1.4 petabytes of raw data. For context, 1.4 petabytes is roughly 1.4 million gigabytes. From a speck smaller than a grain of rice.

Now scale that. The full human brain is one million times larger. Mapping the whole thing at this resolution would produce approximately 1.4 zettabytes of data. That’s roughly equal to all the data generated on Earth in a single year. The storage alone would cost an estimated $50 billion and require a 140-acre data center, which would make it the largest on the planet.

And they found things textbooks don’t contain. One neuron had over 5,000 connection points. Some axons had coiled themselves into tight whorls for completely unknown reasons. Pairs of cell clusters grew in mirror images of each other. Jeff Lichtman, the Harvard lead, said there’s “a chasm between what we already know and what we need to know.”

This is why the next step isn’t a human brain. It’s a mouse hippocampus, 10 cubic millimeters, over the next five years. Because even a mouse brain is 1,000x larger than what they just mapped, and the full mouse connectome is the proof of concept before anyone attempts the human one.

We’re building AI systems that loosely mimic neural networks while still unable to fully read the wiring diagram of a single cubic millimeter of the thing we’re trying to imitate. The original is 1.4 petabytes per millionth of its volume. Every AI model on Earth fits in a fraction of that.

The brain runs on 20 watts and fits in your skull. The data center required to merely describe one-millionth of it would span 140 acres.

[Liam @liamcubed]

@tominsalem @providence @marquette @yukon @seton and Providence (NET: 76) is just one spot away from Quad 1

[Liam @liamcubed]

@algekalipso it’s very validating, and it’s a great way to expand what your “passion” really is. my first encounter with you at PhilaDelic was definitely mind opening for me 🙂

[Liam @liamcubed]

@CullenGoRedmen @hoops_mike “Jackson starts at PG” 🥲🥲

[Captain Pleasure, Andrés Gómez Emilsson @algekalipso]

For a wide range of people: doing a little metta meditation everyday (even if just 5-10 minutes) for all of 2026 is up there as one of the highest leverage things you could do. Maybe it's not for you, maybe you're already on it, but just in case - this is the signal you're waiting for 😉

[Liam @liamcubed]

@liquidprismata @TylerAlterman yeah this could not exist in NYC, 72-hour parties at Nowadays would be the closest thing

[Liam @liamcubed]

so pleased to own this book

[Liam @liamcubed]

@LukeChrisFFL Mcbride tied for 1st in receptions

[Liam @liamcubed]

@danallison yayayayay Dan 🙂 excited for mine to arrive 🙂

[Liam @liamcubed]

this is a Davante Adams tweet

[Peter Schrager @PSchrags]

In 2020, Aaron Rodgers threw 48 TD passes and just 5 INTs. I never thought we'd see a bigger gap in TDs to INTs in a single season.

Through 11 games, Matthew Stafford has thrown 30 TDs and just 2 INTs.

Simply remarkable run the last two months from Stafford.

[Liam @liamcubed]

@algekalipso yup I wore this pin at Psychedelic Science, definitely proud to be involved in this space :)

[Liam @liamcubed]

this Don Draper quote is a great tldr for this paper on entropy → insight.

[Robin Carhart-Harris @RCarhartHarris]

Thoughts on this? Entropy & Insight... "The Self-Organization of Insight" by Damian G. Stephen and James A. Dixon https://t.co/wWIKODv5w4

[Liam @liamcubed]

@RCarhartHarris Insight as a phase transition explains why meditating is often a more productive problem-solver than just "thinking really hard”

[Liam @liamcubed]

@justalexoki never do anything so you can never make the wrong decision