Michael McKeown

Cancer researcher and politics enthusiast

[Michael McKeown @lifescilife]

3% GDP growth sounds good except the investment and exports are down, consumer spending weak. Entirely driven by a collapse of imports.

[Michael McKeown @lifescilife]

@adamfeuerstein looks like the zombie company problem spread from biotech to tech https://t.co/3GvOpuP8hP

[Michael McKeown @lifescilife]

Disappointed to see the FDA talked down about and labelled 'deep state'. All bureaucracies can be improved, but my interactions with them have always been data driven and efficient. Also, FDA is partly funded by user fees so cuts make no sense. https://t.co/eP3RyjlOyk

[Michael McKeown @lifescilife]

So, 200M in munitions burned... this would have funded a lot of education and healthcare. https://t.co/ONEl5iwJv8

[Michael McKeown @lifescilife]

I just wanted to share this link. It is a helpful compilation of recent political events impacting science. Also, the contacts link let's you can share how you have been impacted directly. NSF/NIH funding for SBIR is very important for small biotech. https://t.co/8nymIfXRZK

[Michael McKeown @lifescilife]

there has been a lot of talk about "vibe-cession" where the economy is "doing great actually". Well, in biotech it is still in a slump and these layoffs have a huge impact on a small, regional sector like life sciences https://t.co/7lvNFow92l

[Michael McKeown @lifescilife]

this is a very encouraging sign of a thaw in biotech. seems like the risk profile preferences are just starting to shift back to earlier programs and companies https://t.co/xZwSELkyy3

[Michael McKeown @lifescilife]

well, this is going to require some revised plans: https://t.co/4p51wLoJO1

[Michael McKeown @lifescilife]

So, who is trying the total synthesis on this one? Complicated natural product from a truly massive enzyme https://t.co/1ifTbRUUwM

[Michael McKeown @lifescilife]

But wouldn't lower revenue projections reduce capital investment eventually? I am not convinced that the IRA is a big problem, but the funding factors identified here are not independent. https://t.co/b1ZuOWksuk

[Michael McKeown @lifescilife]

@Noahpinion But isn't the optimistic view here that even just $50/month plus checks ins cut homelessness in half? The line plots show range so it clearly was significant.

[Michael McKeown @lifescilife]

I have seen a fair amount of this. The human and animal data match, but the animal data itself would not have been an objectively strong response by clinical criteria. https://t.co/KpsKmYuwqd

[Michael McKeown @lifescilife]

Glad this is getting more coverage. Drug cost problems are a lot more complicated than just blaming manufacturers and research
The Opaque Industry Secretly Inflating Prices for Prescription Drugs https://t.co/RaNWrdZaHt

[Michael McKeown @lifescilife]

Not efficacious or safe?
https://t.co/q7JzdgvOUf

[Michael McKeown @lifescilife]

biologics sweeping the top 11 out of 20 https://t.co/ENO3MM1tYc

[Michael McKeown @lifescilife]

I really appreciate this step toward re-centering academic research toward education and mentoring. https://t.co/xxCzfOQA9i

[Michael McKeown @lifescilife]

I really appreciate the continued effort to provide public sources of genomics data. COSMIC, TCGA, DepMap, cBioPortal, and others have been immensely helpful to the research community. https://t.co/I1HteydA9A

[Michael McKeown @lifescilife]

Yikes! I feel like 15 years ago we were worried about "reproducibility". Seems like it has continued to snowball https://t.co/jL0NrQow4c

[Michael McKeown @lifescilife]

There is a point where environmentalism is counter productive. Opposition to nuclear as a replacement for carbon is one. GMO rice is another https://t.co/8qsvmlAXjS

[Michael McKeown @lifescilife]

There is a lot of AI and things posing as AI going around but we have to find the right high value applications. I have worried about this is science but a broader problem as well https://t.co/dUC6UqPsMu