These were my favorite reads in 2023, the books that have influenced my thinking the most:
Change by Damon Centola
Speed & Scale by John Doerr
Elon Musk by Walter Isaacson
The Vital Question by Nick Lane
The Big Picture by Sean Carroll
We report an AT-rich RNA structure, termed CRISPR separator, that can enhance crRNA array processing and multiplex gene regulation.
Congratulations to Jens Magnusson @Liflock!
Enhanced Cas12a multi-gene regulation using a CRISPR array separator https://t.co/fHWKti8tCY
In our latest study, we find that Cas12a CRISPR arrays are sensitive to spacer GC content. Inspired by naturally occurring CRISPR arrays, we introduce AT-rich “separators” that act as insulation and enable enhanced multi-gene regulation in human cells. https://t.co/IPkNtXMZet
“The brain is very bad at replacing dead neurons...”
As Jens Magnusson @Liflock explains, the extraordinary discovery that astrocytes can act like neuronal stem cells might challenge that notion going forward.
More in the latest 🎧 #eLifePodcast https://t.co/Nm4kzKiuEl
Always, always speak respectfully. Go private. Every little bit helps. These are three of our 10 tips for debunking conspiracy theories convincingly—and kindly. https://t.co/KRkId63BLf
Astrocytes, one of the most abundant cell types in the brain, are upstream of neural stem cells in the neuronal lineage and may be regarded as highly quiescent neural stem cells. https://t.co/ilSpPdgaMv
Halting funding for the World Health Organization during a world health crisis is as dangerous as it sounds. Their work is slowing the spread of COVID-19 and if that work is stopped no other organization can replace them. The world needs @WHO now more than ever.
”To stop COVID-19, test everyone, repeatedly.” Me and Jussi Taipale propose a simple strategy to defeat coronavirus, and pose a challenge to the scientific community. https://t.co/q4xTpbRkVJ
We are looking for collaborators to develop delivery strategies for our anit-COVID-19 work. Is this you? Get in touch! #COVID19#CRISPR https://t.co/KJsnHYYOPQ
The scientific community is having a conversation about reproducibility. Now, political activists are using it for their own ends https://t.co/EXdiLyb4CP