I am thrilled to share that I have joined the faculty in the Department of Urology at UCSF!
I am so grateful for the support of my exceptional mentors, colleagues, and trainees who have contributed to this milestone.
Looking forward to what’s ahead for the Chesner Lab!
A milestone of our photopharmacology ERC project, just up on bioRxiv! Light-dependent control of network activity in human brain tissue of patients with epilepsy &/or brain tumors using lidocaine photoswitches & a novel photocaged propofol. 1/2
https://t.co/XkMQbNgSur
Did you see him help someone?
Did you see him try to run?
Did you see them six-on-one?
Did you see them take his gun?
Did you see that it was done?
Did you see him get shot a dozen
times in broad daylight?
Do you think they'll kill again?
🎉 Join us on Monday for the best party of the year!
The Cai-Tye Collective is throwing a bash at #SfN25 and everyone is invited!
🎉 November 17, 9pm at Parq Nightclub in San Diego. See you all there!
🧠 The Cai Lab will be at #SfN25!
Be sure to stop by the poster sessions to check out @Hailey_lr's work on decision-making, Zach's work on stress & the amygdala, @ZoeChristenson's work on seizures, Alexa's work on cocaine seeking, and Sandra's work on context representations 🤓
Are you at #SfN25 and want VIP access to the Cai-Tye Collective event on Nov 17?
Come by my lab members' posters for a bracelet!
Hailey Rosenblum: Nov 15, 1-5pm PSTR040.05/BB6
Zoé Christenson Wick: Nov 17, 8am-12pm PSTR192.01/RR13
Zach Pennington: Nov 17, 1-5pm PSTR234.05/CC7
Just out! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory https://t.co/po9zIlZvPb. New astrocyte tools are openly available at Addgene: https://t.co/OXCmcYSleI. 1/8
Working with trainees is a highlight of my own research and a main goal of the New York Memory Hub. I'm looking forward to a great afternoon of discussion with a group of brilliant trainees. Space is limited, register soon!
Presidential Lecture at #senc2025 by Prof Alfonso Araque. The live history of Tripartite Synapse and revolution in Neurosciece. Very proud of Spanish Science! @LabAraque @InstitutoCajal @CSIC@SENC_
New paper out in @CellReports! Led by @susie_feng, we found that chronic epilepsy in mice drives distinct synchronization deficits in hippocampus and MEC, with early changes in HPC and late-onset changes in MEC that align with progressive memory deficits.
https://t.co/26cGcv1HBg
New preprint from the lab! @laurenmvetere found disrupted MEC-hippocampal synchronization that paralleled the emergence of memory deficits in the 3xTg mouse model of AD pathology!
Check it out and let us know what you think.
Astrocyte physiologists and computationalists!
Imaging astrocyte structure and function, we discovered and quantified a spatial threshold to astrocyte calcium surge ⭐
https://t.co/Jv8Ph6dn6k
🌟 Cai Lab @Nature paper alert! In new work led by @mysteriousjoe_, we find that rest periods after learning not only stabilize new memories BUT ALSO integrate new memories with older ones from days past! (1/9)
Read it here: https://t.co/Ur8dbGfuP3
📣 New Cai Lab paper in @CellReports!
We show that a stressful experience can produce different types of memories! We also find that the basolateral amygdala (BLA) & ventral hippocampus (vHC) differentially contribute to these memories 🧠
https://t.co/GV9gyu4Gmf
More ⬇️ (1/6)