Lorenzo Barba

MD, Neurology, University Hospital Halle (Saale) 🇮🇹🇩🇪 currently working on fluid biomarkers in neurological diseases 🩸👨🏻‍⚕️🧠

[Lorenzo Barba @lorbarba]

Excited to see our latest work on serum synaptim markers out in @JNNP_BMJ !
Nice collaboration of German, Italian and Spanish groups 🧠

@s_rumeileh
https://t.co/BFYnifEBzu

[Samir Abu Rumeileh @s_rumeileh]

Check out our new study!
☑️p-tau 181 and 217 in blood are not as specific for AD as previously thought,
☑️they are also elevated in the blood of patients with ALS,
☑️IHC and MS analyses disclosed both p-tau species in muscle biopsies from ALS cases.
https://t.co/nhyQdQ6hms

[Lorenzo Barba @lorbarba]

Very pleased to see our article out! We explored for the first time CSF synaptic biomarkers (SNAP-25, ng, beta-synuclein) in MS and found that reduced biomarker levels are associated with brain atrophy at MRI and cognitive impairment 🧠

@s_rumeileh
https://t.co/lytZ2BY9lY

[Cambridge FTD @CambridgeFTD]

Fantastic morning at the #DGN Kongress 2024 Berlin, discussing #SynapticHealth and synaptic biomarkers in blood, CSF, PET and pathology. Thanks to Markus Otto, Patrick Oeckl, Dietmar Thal @lorbarba and @M_Malpetti and the great audience @wbic_cam @DementiasUK

[Lorenzo Barba @lorbarba]

@lizziehill35 @smead2 Many congratulations Lizzie! 😃

[Avramiotis S. Nikolaos, MD, MSc @NSAvramiotis]

🚨Just published in @ESOstroke: Antithrombotic drugs for carotid artery dissection: Updated systematic review🚨

Weak evidence for #antiplatelets as standard for #carotidarterydissection. Treatment individualization is warranted!

Full article here: https://t.co/VV6Cmamjbs

[UPittStroke @PittStroke]

Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial - The Lancet Neurology https://t.co/x14SKHnv4i

[Michele Romoli @MicheleRomoli]

When small vessel disease #SVD is mixed with #CAA signs, amyloid PET may help identify people at higher risk of cerebral bleeding 🩸🧠
Have a look at our study out in
@GreenJournal
@BenStorti
@NeuroBesta
@AUSLRomagna
@CAA_Disease
@ISA_AII_Young
https://t.co/o1r9H5eviS

[JAMA Neurology @JAMANeuro]

Is left atrial appendage occlusion a valuable treatment option for patients with atrial fibrillation and #breakthroughstroke despite anticoagulation therapy? @davidseiffge @boersma_lucas https://t.co/AhCVGfocME

[Lorenzo Barba @lorbarba]

@sciqst @Brain1878 Along the usual pTau isoforms (even though the pathological correlates in LBD are still uncertain) the group of CSF and blood synaptic biomarkers (SNAP-25, neurogranin, beta-synuclein etc.) seem to be very promising!

[Brain @Brain1878]

Barba et al. review the co-occurrence of Alzheimer's disease and Lewy body disease pathologies, and consider the diagnostic and prognostic value of neuroimaging and fluid biomarkers. https://t.co/M4GgccTbt2

[Brain @Brain1878]

Barba et al. review the co-occurrence of Alzheimer's disease and Lewy body disease pathologies, and consider the diagnostic and prognostic value of neuroimaging and fluid biomarkers. https://t.co/M4GgccTbt2

[Lorenzo Barba @lorbarba]

@Ahmed_Abdelhak_ @Brain1878 @s_rumeileh @fedemassa88 @mattfos89 @unimedizinhalle Many thanks Ahmed!!

[Lorenzo Barba @lorbarba]

Extraordinarily excited for our work to be published in @Brain1878 today!

We extensively discuss the clinical and diagnostic implications of #Alzheimer’s disease copathology in Lewy body disease 🧠

@s_rumeileh
@fedemassa88
@mattfos89
@unimedizinhalle

https://t.co/gnU1BNbLwb

[Journal of Neurology, Neurosurgery and Psychiatry @JNNP_BMJ]

This fantastic study shows ALL even low levels of physical activity benefit the brain by reducing stroke risk. 🧠 🏃

👇
https://t.co/L2yEYRp6ae

By
@RaffaeleOrnello
@s_rumeileh
@mattfos89
@fededs00
@MicheleRomoli
@luciodanna2
@Simona_Sacco_
@lorbarba et al

[JAHA @JAHA_AHA]

Curious about the feasibility of mechanical thrombectomy after ischemic stroke in the context of cardiac diseases? #AHAJournals #Review @luciodanna2 @s_rumeileh @giovmerl @mattfos89 @lorbarba @simona_sacco_ @NguyenThanhMD https://t.co/zZ8N1JFSbE

[Lorenzo Barba @lorbarba]

Excited for our review on MT in AIS due to cardiological disorders 🧠🫀
A great effort from a great team!

@luciodanna2
@s_rumeileh
@mattfos89
@MicheleRomoli

[luciodanna @luciodanna2]

Finally Out our review exploring for the first time the safety and efficacy Mechanical Thrombectomy in Acute Ischemic Stroke Attributable to Cardiological Diseases | Journal of the American Heart Association https://t.co/jDbawSAorw @Simona_Sacco_ @mattfos89 @ESOstroke

[Lorenzo Barba @lorbarba]

Happy to share our last publication on two new CSF markers of neurosecretory pathways impairment (VGF and neuroserpin) 💧 those biomarkers were associated with AD pathology and cognitive impairment in AD and LBD 🔬🧠

@s_rumeileh

https://t.co/EBRhV5dFWF

[Lorenzo Barba @lorbarba]

Only 12 cases in literature of PRES associated with administration of antibiotics. We reviewed these cases to raise attention on this not negligible neurological syndrome 🧠🦠💊

@s_rumeileh
@mattfos89
@luciodanna2

https://t.co/gLSwn2ApkH

[Journal of Neurology, Neurosurgery and Psychiatry @JNNP_BMJ]

This fantastic study shows ALL even low levels of physical activity benefit the brain by reducing stroke risk. 🧠 🏃

👇
https://t.co/L2yEYRp6ae

By
@RaffaeleOrnello
@s_rumeileh
@mattfos89
@fededs00
@MicheleRomoli
@luciodanna2
@Simona_Sacco_
@lorbarba et al