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Almost every cell you can think of secretes RNAs, including neurons. But how are specific RNA molecules selected for extracellular export?
We set out to address this question in our latest preprint:
https://t.co/meUkKUynAb
A long-overdue thread 🧵
New OA Brief Comm: "Cross-kingdom RNA interference promotes arbuscular mycorrhiza development" https://t.co/z5sScfXlq5
Symbiotic fungi forming widespread arbuscular mycorrhiza symbioses use cross-kingdom RNAi to silence plant genes and promote their colonization of host roots.
Nucleosome aficionados! Our new review "Nucleosome spacing across cell types, diseases, and ages" is out in NAR: https://t.co/Z1TgEYxBH8
A huge effort to pull together what we’ve learned about nucleosome spacing in many systems. Enjoy!
#nucleosomics#nucleosome#chromatin#cfDNA
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I’d like to thank everyone involved—labmates, collaborators, and especially Roberto, who gave me the opportunity to pursue this “wild” project and supported me every step of the way.
1/
Almost every cell you can think of secretes RNAs, including neurons. But how are specific RNA molecules selected for extracellular export?
We set out to address this question in our latest preprint:
https://t.co/meUkKUynAb
A long-overdue thread 🧵
16/
The genetic identification and biochemical validation of this and other mechanisms governing exRNA selection will help uncover the biological functions of extracellular RNAs and ultimately decode the language of RNA-mediated cell-to-cell communication.