Luke Taplin-McCallum

Adtech, startups, building things.

[Luke Taplin-McCallum @luketapmc]

@Emily21409809 @PokemonStockUK And what does it say in the status of the order on Pokémon centre website?

[Luke Taplin-McCallum @luketapmc]

@Emily21409809 @PokemonStockUK Did you get an email saying this?

[Luke Taplin-McCallum @luketapmc]

@antonioventre_ I'd challenge this. Creative can account to 50% of a campaign's effectiveness. Yes, strategy, targeting, conversion tactics and how the funnel is stitched. Creative is THE biggest lever we can single handedly control.

[Luke Taplin-McCallum @luketapmc]

@Citizen_Sally Thanks for picking this one up, Sally

[Luke Taplin-McCallum @luketapmc]

@theboganguru @morellifit Don’t touch any of them. We do not know the long term sides, but the consensus is stay away if you or your family members have had cancer

[Luke Taplin-McCallum @luketapmc]

Glycinate at night is usually the gentlest form and many notice they relax and sleep better, especially if they’re running low from stress, alcohol, or crappy diet.

That said, the “most people are deficient” claim is a bit overstated. Subclinical low levels are pretty common (around 40-50% don’t hit the RDA), and studies do show modest improvements in mild anxiety and sleep quality for those who are low. But it’s not a miracle fix for everyone - results vary a lot person to person.

Reducing alcohol and processed food plus eating more mineral-rich stuff (leafy greens, nuts, seeds) is honestly the smartest starting point before adding pills.

I used to throw magnesium and a bunch of other calming supps (glycine, taurine, theanine, etc.) into my stack thinking more was better, only to realize I was overlapping on the same pathways and not getting extra benefits. That’s why I built Evidose (https://t.co/EpLJ7kHNV5) it collates over 50,000 pieces of published research so you can see what’s actually worth keeping in your stack without the guesswork.

[Luke Taplin-McCallum @luketapmc]

Magnesium + B6/D is a pretty common starting combo — mag for calm and sleep, D for energy (especially if you don't get much sun), and B6 can help with the mag absorption.
I'd start with just those two and see how you feel before adding more. I kept adding random supps and ended up overlapping on a bunch without extra benefit. That's why I made Evidose (https://t.co/EpLJ7kHNV5) to pull from over 50,000 research papers and figure out what's actually worth taking in a stack

[Luke Taplin-McCallum @luketapmc]

everyone really is different. Magnesium, D3 + K2, and collagen/glycine are solid basics that a lot of people notice help with sleep, energy, and joints.
The hard part is knowing what you actually need versus what overlaps and does nothing extra. I used to throw a bunch of stuff in my stack and realize later I was doubling up on similar pathways. That's why - cue ad - I built Evidose (https://t.co/EpLJ7kHNV5) that collates over 50,000 pieces of published research to check full stacks

[Luke Taplin-McCallum @luketapmc]

Zinc + mag glycinate is a popular combo for a reason — mag helps with sleep and recovery, zinc supports hormones and immunity. A lot of ppl notice better energy and mood when they're actually low in them.
Just don't go crazy high on zinc long term (15mg or less is usually plenty). I used to throw random things into my stack and overlap without noticing until I built Evidose (https://t.co/EpLJ7kIlKD) that collates over 50,000 pieces of research to see real interactions

[Luke Taplin-McCallum @luketapmc]

Joint aches suck at any age. Common ones people reach for are collagen (10-20g daily), omega-3 fish oil, and sometimes MSM or turmeric/curcumin for inflammation. Magnesium can help with muscle cramps too.
Start with one or two and see how you feel rather than stacking everything at once. I used to overlap on a bunch of supps and waste money until I built Evidose (https://t.co/EpLJ7kHNV5) that pulls from over 50,000 research papers to break down what's actually backed

[Luke Taplin-McCallum @luketapmc]

@LeddyLLC people should chuck their goals/needs into https://t.co/qamKunUNPC and get evidence-based recommendations for them

[Luke Taplin-McCallum @luketapmc]

I kept wasting money on supplements and realised I was overlapping on a bunch of stuff that hit the same pathways. Got tired of guessing about safety and what actually works.

So I built Evidose (https://t.co/EpLJ7kHNV5) that collates over 50,000 pieces of published research to break down ingredients and full stacks.

[Luke Taplin-McCallum @luketapmc]

This is a pretty solid take. Those four have the strongest research behind them for most people when youre actually low or training hard. Creatine for power and brain energy, mag for recovery, D if youre not outside much. Good call skipping the hype stuff until the basics are covered. If you ever want to test a bigger stack I made Evidose (https://t.co/EpLJ7kHNV5) to pull the real studies on combos.

Happy to test your app too btw if you wanna share it

[Luke Taplin-McCallum @luketapmc]

Spot on about the dosing scam. A lot of blends throw in tiny amounts of ashwagandha or tongkat just for the label and it does basically nothing. Real studies use much higher doses for any effect. Better to buy single ingredients and dose them properly. I put together Evidose (https://t.co/EpLJ7kHNV5) exactly to check actual evidence levels on stuff like this.

[Luke Taplin-McCallum @luketapmc]

Yeah creatine pulls water into your muscles so that quick weight gain is normal at the start. Most people just aim for an extra litre or two of water a day and it levels out. The strength and recovery benefits are still worth it for a lot of folks. If youre running it with other stuff I made Evidose (https://t.co/EpLJ7kHNV5) to check the research on the whole stack

[Luke Taplin-McCallum @luketapmc]

Sorry to hear that. Quality control on NMN is all over the place especially from big marketplaces. A lot of people end up testing their own or sticking to brands with third party verification. If youre still thinking about NMN or similar longevity stuff I built Evidose (https://t.co/EpLJ7kHNV5) to pull real research on effectiveness and safety.

[Luke Taplin-McCallum @luketapmc]

Smart to check for interactions. Magnesium and glycine are usually fine together and a lot of people like them for calm and sleep. NAC can be helpful too but starting new things one at a time makes it easier to tell what is doing what. I made a tool called Evidose (https://t.co/EpLJ7kHNV5) that checks stacks against published studies if you want to run your list through it.

[Luke Taplin-McCallum @luketapmc]

10g collagen at night is pretty common but the evidence for big sleep improvements or Oura changes is still pretty light for most people. It can help with skin and joints over time though. Might be worth trying 5 to 10g for a few weeks and see how you feel. If you combine it with other supps I put together Evidose (https://t.co/EpLJ7kHNV5) to look at the research on stacks like that

[Luke Taplin-McCallum @luketapmc]

Good point on the brain side. A lot of people only think creatine is for lifting but the research shows it helps with mental energy too especially if sleep is off. The sports science data is super solid after all these years. If youre stacking it with anything else I made Evidose (https://t.co/EpLJ7kHNV5) that pulls from the studies to spot any issues.

[Luke Taplin-McCallum @luketapmc]

Strong take—creatine, mag glycinate, and D+K2 really do have the best evidence for most guys. Creatine for performance + cognition, mag for sleep/stress, D when deficient. Solid foundation before adding anything else. If you're testing a full stack, I built Evidose (https://t.co/EpLJ7kHNV5) to cross-check against published research."