Liangliang Zhang

Assistant Professor, Biostats, Bioinfo, Bayesian, -Biome @ Case Western Reserve University

[Liangliang Zhang @lyonszhang]

Impressive scale and resolution—over 600K cells across 97 individuals.

#SingleCell #Immunology #HostResponse

Single-cell atlases like this are essential for decoding host immune heterogeneity and disease severity.

[iMeta @iMetaScience]

👏A large-scale single-cell transcriptomic atlas indicates the immune panorama of influenza A infection
We generated a large-scale single-cell transcriptomic atlas from peripheral blood, profiling more than 612,010 cells from 97 individuals.
#HostResponse
https://t.co/J6LNrrZL6Q

[Liangliang Zhang @lyonszhang]

Interesting new work in @iMetaScience @WileyHealth introducing a Two Competing Guilds (TCG) framework for microbiome analysis, which highlights the value of community-level ecological structure beyond single-taxon biomarkers.

[iMeta @iMetaScience]

Two stable gut microbiome guilds predict liver tumor class and treatment responses

⚙️ Functionally opposing microbial guilds highlight an ecological basis for tumor progression and clinical outcomes. #Hepatocellular @WileyHealth
https://t.co/QVa6EJm3wO

[Liangliang Zhang @lyonszhang]

USEARCH 12: Open‐source software for sequencing analysis in bioinformatics and microbiome - Zhou - 2024 - iMeta - Wiley Online Library https://t.co/gUcYymah8j

[iMeta @iMetaScience]

Deep learning enhancing guide RNA design for CRISPR/Cas12a-based diagnostics
https://t.co/dtjHkMCeLS

[Liangliang Zhang @lyonszhang]

Sometimes in research, everyone thinks they have the answer. The postdoc wants to guide, the PhD student wants to prove themselves, and the PI just hopes the science moves forward. But when ego replaces collaboration, even good ideas can turn into a mess.

[PhD_Genie @PhD_Genie]

New PhD candidate, a postdoc and the PI

[iMeta @iMetaScience]

Duck gut metagenome reveals the microbiome signatures linked to intestinal regional, temporal development, and rearing condition
https://t.co/Ud3LFdIa1F

[Zhenrun Jerry Zhang @SZhangJerry]

Genome Biology is calling for submissions to the Collection "Non-bacterial metagenomics", which focuses on methods and applications that broaden metagenomic inquiry beyond bacteria! https://t.co/g0mYqwYgy9

[iMeta @iMetaScience]

🤔 Curious what #iMeta is and why we reached IF = 33.2 in just 3 years? 🚀
⚡Wondering how we process manuscripts so fast while driving cutting-edge discoveries?
🎥 Watch this short video — the answers are here.
More details about iMeta: https://t.co/8hXrZ2DlJX
#Bioinformatics #microbiome #journal #sciencecommunication @wileymicrobio @WileyBiomedical @WileyOnc_Hem @WileyEcolEvol

[Liangliang Zhang @lyonszhang]

I’m excited to share our in-depth review and advancement of transformation methods for compositional data with excessive zeros. @zhang_yiqian_ @jonasschluter @HHarryFeng

Review and Revamp of Compositional Data Transformation: A New Framewor... https://t.co/FQxRTkw5zC

[Liangliang Zhang @lyonszhang]

If you are interested in the microbiome tree construction and the concordance between 16S rRNA and WGS. Please check out our paper on @CSB_Journal . Authors @burdungy_Liu @dmln1111

Constructing phylogenetic trees for microbiome data analysis: A mini-r... https://t.co/jhRazyfX5a

[Liangliang Zhang @lyonszhang]

Attending 2024 Case Comprehensive Cancer Center(CCC) Microbiome Workshop https://t.co/J6NTGdwDxP

[Liangliang Zhang @lyonszhang]

@scottmwilliams9 @WiringTheBrain Agree. Sigh, there is no overarching law in human medicine comparable to Newton’s law of universal gravitation.

[CWRU-CINEMA @CwruCinema]

I am honored to attend the NSF 2023 MPS Workshop for New Investigators. I learned a lot about the funding application process and got my questions answered. Excitingly, I made friends and we got a chance to visit the NSF building. Many thanks to @NSF @UF @cwru

[Scott Williams @scottmwilliams9]

A message to all academics - skip Texas. So Iguess solution is do not give notive - just leave. I know when I was a grad student my PI moved and UT-Ausitn held onto his grants as long as possible. But this is really extreme.

[Liangliang Zhang @lyonszhang]

Last year, we assistant professors discussed about hiring a secretary to relieve us from lots of paperwork and document management. With Microsoft 365 copilot, it seems that we don’t need one anymore. @holly7holly @HHarryFeng @yilun_sun @JinKimMoz

[Microsoft @Microsoft]

How much of your day is spent drafting emails, preparing presentations, or staring at a blank page? AI can help lighten the load.

Introducing @Microsoft365 Copilot—the next era of work: https://t.co/1DjXfsJvyj

[Liangliang Zhang @lyonszhang]

Inspirational individuals and captivating stories of persevenrance are the canstant reasons why I hold a deep appreciation of the world！

[The Academy @TheAcademy]

"Mom, I just won an Oscar!"

Ke Huy Quan's acceptance speech for Best Supporting Actor hit us right in the feels. 🥹

[Liangliang Zhang @lyonszhang]

@scottmwilliams9 This is another example that it is easier to tell the correlations than causal effect.

[Liangliang Zhang @lyonszhang]

I am wondering what can be evaluated by exam then. Problem solving, reasoning, creativity, and critical thinking? But why are we used to giving admission offers to students with high GPA in top-ranked schools?

[CNBC @CNBC]

OpenAI announces smarter AI model called GPT-4, claims it can beat 90% of humans on the SAT https://t.co/aUDXkhoMFl

[Liangliang Zhang @lyonszhang]

@scottmwilliams9 True. Why does everyone have to use p-value, though it does not make any sense in many scenarios? Researchers have been restricted in the scope of “golden standard” for so many years.

[Liangliang Zhang @lyonszhang]

@ttpizarro @GiuseppePrivi @nitishrana @alearmuzzi Congrats，Theresa!