کریٹنن لیول بڑھ جائے تو بندہ اسی طرح ہوش کھو بیٹھتا ہے، فسٹولہ بند ہو گیا ہفتہ بھر ڈائلسس نہ ہوئے اور بندہ کسی کو پہچان بھی نہیں رہا تھا، ماں کے پاس پیسے نہیں تھے کہ کوئی بندوبست کر سکے
ایمرجنسی لائن ڈلوا کے ڈائیلسس شروع ہوا تو بیچارے کو سکون ہوا، اٹھارہ ہزار مدد کی گئی
💊DRUG OF THE DAY #014: SPIRONOLACTONE
⚠️ EDUCATIONAL ONLY, NOT MEDICAL ADVICE
LICENSED PHARMACIST SHARING GENERAL DRUG INFORMATION.
CONSULT YOUR DOCTOR OR PHARMACIST BEFORE MAKING ANY CHANGES TO YOUR TREATMENT.
Spironolactone is a potassium-sparing diuretic that works by blocking the effects of aldosterone, a hormone responsible for sodium and water retention. Unlike loop and thiazide diuretics, spironolactone helps the body eliminate excess fluid while conserving potassium.
It is widely used in heart failure, resistant hypertension, liver cirrhosis with ascites, and primary hyperaldosteronism. Beyond its diuretic effect, spironolactone has demonstrated significant mortality benefits in patients with heart failure with reduced ejection fraction (HFrEF).
📌 Key Clinical Pearl:
Spironolactone is often prescribed not only to remove excess fluid but also to block the harmful long-term effects of aldosterone on the heart and blood vessels. In heart failure, its benefits extend beyond diuresis to improving survival.
✅ Improves outcomes in heart failure (HFrEF)
✅ Effective for resistant hypertension
✅ Useful in ascites due to liver cirrhosis
✅ Helps conserve potassium compared with other diuretics
⚠️ May cause hyperkalemia
⚠️ Gynecomastia can occur in males
⚠️ Renal function should be monitored regularly
⚠️ Avoid unnecessary potassium supplements unless advised
As pharmacists, we play an important role in monitoring potassium levels, assessing renal function, counseling patients on adverse effects, and promoting safe use of mineralocorticoid receptor antagonists.
"Monitoring potassium is just as important as prescribing the medication."
#DrugOfTheDay #Spironolactone #HeartFailure #Hypertension #Diuretics #ClinicalPharmacy #PatientSafety #Cardiology #HospitalPharmacy #PharmaAmeer
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