Mallika Dhawan

oncologist, early phase drug development, @ucsfcancer @genentech

[Sumanta K. Pal, MD, FASCO @montypal]

Congrats to @PGrivasMDPhD @fredhutch & colleagues for a terrific paper out now in @CCR_AACR. A massive effort to characterize the activity of #Debio1347, a novel FGFR inhibitor. 63 pts enrolled in total with a RR of 5%; 45% w SD. Lots of rich information in this paper w rich transcriptomic data provided across the cohort: https://t.co/WzPZr1C9Mr

[Mallika Dhawan @mallika_onc]

@FiedlerAmy @UCSFHospitals @UCSFCTSurgery @UCSFSurgery @LiviuKlein @JasonWSmithMD @Jasosamd @MandarArasMD 👏👏👏👏👏

[Rebecca Shatsky, MD @Dr_RShatsky]

This has been a long time coming.

[Bob Wachter @Bob_Wachter]

This was a terrific session on #LongCovid, by 3 international leaders in LC. We've made significant progress in understanding the causes of the disease & the epidemiology, but still lack evidence-based therapies. Hope that changes soon. Available here: https://t.co/LV3EWxYjQ0

[Ashish K. Jha @ashishkjha]

COP 28 is happening and while folks are wondering what will come of it

One big thing already has

In the past, we rarely saw health folks at COP

That changed this year

100 health ministers/leaders are @COP28_UAE

This is a sea change. Here's why this is so important

A🧵

[Dr. Glaucomflecken @DGlaucomflecken]

2 years undergrad (pre-reqs only)
2 years+3 days med school
3 years residency
6 months fellowship

Board certified nephrologist screaming about sodium by age 24

[Vivek Subbiah, MD @VivekSubbiah]

How to build a successful phase 1 program?
✅Phase I physicians should be those who are ready to see patients across the malignancy spectrum.
✅Faculty and staff for an early-phase unit should be fully focused on this work, and not doing it as a “side hobby.”
✅Patients should be prescreened before clinic for protocol eligibility, and the basic principle of the patient comes first must be followed—hence co-ordinators should wait for the patients, not vice versa.
✅Finally, for phase I unit leaders and team members, education must be an iterative process for their lifetime with the unit, & encompass a wide variety of topics, from regulatory compliance to emerging science, response and toxicity review, and molecular tumor boards @Dr_R_Kurzrock @DavidHongMD 👏

[Nate Bear @NateB_Panic]

In July 2021, New York Magazine headlined a story: The Kids Were Safe From Covid The Whole Time.

"Mortality risk is actually lower than from the flu" it said.

The kids, flu and covid:

[Julia Maués @itsnot_pink]

Sept 25, 1998, 23 yrs ago, @FDAOncology approved @genentech’s #Herceptin. It’s hard to overstate the importance of patients & researchers who made this happen. 😉 @NobelPrize!

But the biggest prize? TIME.

MBC while pregnant in the first picture, 8-year old in the second.

🙏🏼

[Drew Comments @sjs856]

Remind. Refine. Re-Up: WHAT COVID BOOSTERS ACTUALLY DO #DrewComments

[Mallika Dhawan @mallika_onc]

@manjuggm Yes on pax

[Mallika Dhawan @mallika_onc]

@gradydoctor @JAMA_current So beautifully written.

[Dr. William J. Ripple @WilliamJRipple]

Can you spot the inconvenience?

[Dr. Glaucomflecken @DGlaucomflecken]

Hey @bluecrossidaho do your job please. Immediately. Like right now.

[Mallika Dhawan @mallika_onc]

@AaronGoodman33 Do we need to do MOC or we’re taking the exam every 10? I thought it was one or the other ?

[Mallika Dhawan @mallika_onc]

@Dr_R_Kurzrock Her2

[Alexandria Ocasio-Cortez @AOC]

Justice Alito accepted tens of thousands of dollars in lavish vacation gifts from a billionaire who lobbied to cancel the student loan forgiveness.

After the gifts, Alito voted to overturn. This SCOTUS’ corruption undercuts its own legitimacy by putting its rulings up for sale.

[Mallika Dhawan @mallika_onc]

@ElkeAsen @renudhinakaran Can you get a longer course of paxlovid ?

[Mike Hudema @MikeHudema]

Due to hundreds of uncontrolled wildfires across Canada, New York City looks like a post-apocalyptic hellscape.

If you want a prelude of what the world is going to look like if we do not address man-made climate change — this is it.

#ActOnClimate

[Mike Hudema @MikeHudema]

Siberia: Hottest day in history
Canada: 28,000 sq. km burned by wildfires
Antarctic: Sea ice extent lowest on record in May
Japan: 100 rainfall records broken
Global: Hottest May sea surface temperatures on record

There is no time to wait! #ActOnClimate

#climate #energy