Dr. Meme Castellanos

Dr en medicina y músico catolico seguidor de los Lakers.

[Dr. Priyam Bordoloi @DocPriyamMD]

Most of the expensive supplements you take are not getting absorbed and are completely wasted.

​​As a doctor specializing in Internal Medicine, here are 6 rules to stop making expensive urine and actually absorb your nutrients.

1. ​Vitamin D3 + Fat.

[Modern Health @modernHealthMe]

This woman has a dangerously fast heartbeat. The doctor doesn't start with an IV drug.
He asks her to blow as hard as she can into a syringe & then lifts her legs.

Why?

[Dr. Priyam Bordoloi @DocPriyamMD]

Dr. Priyam here. Today, let me teach you how to interpret a Kidney Function Test (KFT) exactly how I do it as an Internal Medicine resident.

By the end, you won't have a single question left. And also KFTs aren't just about kidneys actually. Let me break it down.

[Valor Mental 🧠 @valormental]

Epicteto curó la ansiedad 2.000 años antes de que existiera la terapia.

Nació esclavo. Cojo. Sin nada. Y se convirtió en el maestro que estudiaría un emperador de Roma.

Sus enseñanzas son el manual más crudo para una mente en calma.

7 frases de él que todavía funcionan 🧵

[Luz Mery Ramírez @MeryLuz21226]

2/4

¿Cómo activarlo de forma sencilla? (métodos con respaldo en estudios de HRV)
(Heart Rate Variability o Variabilidad de la Frecuencia Cardíaca)

• 🧘‍♂️ Respiración diafragmática lenta: inhala 4 seg, exhala 6-8 seg. Aumenta el tono vagal en minutos.

• Agua fría en cara/cuello: 20-30 segundos. Activa el reflejo de inmersión y potencia la actividad vagal.

• 🎤 Canto, tarareo o gargareo: la vibración estimula directamente el nervio.

• 😄 Risa genuina, masaje suave en el cuello o yoga.

[Tamir & Tadilat @TamirveTadilat]

Arabalarda bilmemiz gereken bilgilerden…

[Dr. Priyam Bordoloi @DocPriyamMD]

Med students, listen up! Today let me explain how to analyze a Liver Function Test (LFT) step by step.
​Stop looking at isolated HIGH or LOW flags on a lab report. You need to look at the patterns. Here is how you actually read an LFT panel like a CONSULTANT 👇 (1/10)

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. After 40, stop guessing about your health. These numbers tell you whether you're building a long, vibrant life — or quietly declining without knowing it.

I run these on myself. I run them on every patient I care about. Most are cheap bloodwork. All are available now. And together, they paint a picture no standard annual physical will ever give you. Print this. Bring it to your next appointment. Your 60-year-old self will thank you.
ꟷꟷꟷ
𝗙𝗮𝘀𝘁𝗶𝗻𝗴 𝗜𝗻𝘀𝘂𝗹𝗶𝗻
Target: below 5 μIU/mL. Ideal: 3-4.
This is the 10-year warning bell your standard panel completely misses. Your glucose and A1c can look "normal" for a decade while your pancreas is working overtime to keep them there. Fasting insulin catches insulin resistance 5-10 years before your A1c moves. By the time A1c rises, the damage is already extensive.

𝗛𝗢𝗠𝗔-𝗜𝗥
Target: below 1.0.
Calculated from fasting insulin and fasting glucose. The single best measure of insulin sensitivity. Above 1.0 and your metabolism is already under strain. Above 2.5 and you're insulin resistant — even if every other number looks fine.

𝗛𝗯𝗔𝟭𝗰
Target: below 5.4%.
Not below 5.7% — that's the threshold where medicine calls you "prediabetic." By then you've been metabolically compromised for years. Optimal is below 5.4%. Blood sugar mastery is longevity mastery.

𝗧𝗿𝗶𝗴𝗹𝘆𝗰𝗲𝗿𝗶𝗱𝗲 : 𝗛𝗗𝗟 𝗥𝗮𝘁𝗶𝗼
Target: below 2. Ideal: below 1.
Your metabolic health crystal ball. This ratio predicts insulin resistance, cardiovascular risk, and metabolic syndrome better than any single lipid number alone. A ratio above 3.5 is a red flag regardless of what your total cholesterol says.

𝗔𝗽𝗼𝗕
Target: below 80 mg/dL for moderate risk. Below 60 for high risk.
I've written about this extensively. ApoB counts every atherogenic particle hitting your artery walls. A 2024 analysis found 54% of patients had dangerous levels that standard LDL testing completely missed. If you only know your LDL, you're driving with one eye closed.

𝗟𝗽(𝗮)
Test once in your lifetime.
100% genetic. 1 in 5 Americans are elevated. Triples heart attack risk independently of everything else on this list. Diet and exercise cannot lower it. The 2026 ACC/AHA guidelines now recommend everyone be tested. Most never have been.

𝗵𝘀-𝗖𝗥𝗣
Target: below 1.0 mg/L.
You can have perfect cholesterol and inflamed arteries silently preparing to rupture. hs-CRP measures the fire behind the plaque. The JUPITER trial proved that finding and treating inflammation saves lives — even when lipids look fine. If this number is elevated, your mouth, your gut, your metabolic health, and your visceral fat are the first places to investigate.

𝗩𝗶𝘁𝗮𝗺𝗶𝗻 𝗗
Target: 50-80 ng/mL.
Not the bare minimum of 30 your doctor accepts. Suboptimal vitamin D is linked to higher inflammation, weaker immunity, increased cardiovascular events, worse mood, and poorer outcomes across nearly every disease I treat. Supplement D3 with K2 — without K2, calcium deposits in your arteries instead of your bones.

𝗧𝗲𝘀𝘁𝗼𝘀𝘁𝗲𝗿𝗼𝗻𝗲 (𝗧𝗼𝘁𝗮𝗹 + 𝗙𝗿𝗲𝗲)
Men: optimal range 600-1000+ ng/dL total.
Declining testosterone is an independent predictor of cardiovascular death in men. It's tied to insulin resistance, arterial stiffness, visceral fat accumulation, and systemic inflammation. DHEA-S drops 10-20% every decade after 30. Tracking these isn't about vanity — it's evaluating your body's systemic resilience.

𝗕𝗹𝗼𝗼𝗱 𝗣𝗿𝗲𝘀𝘀𝘂𝗿𝗲
Target: below 120/80. Aim closer to 110/70.
Every point above optimal is cumulative arterial damage. Buy a home cuff. Measure morning and evening, seated quietly for five minutes, arm at heart level. White-coat readings in the office miss what's really happening. The smartest $40 investment in cardiac self-care.

𝗩𝗢𝟮 𝗠𝗮𝘅
Men over 40: above 40 mL/kg/min. Women over 40: above 35.
Cardiorespiratory fitness is the single strongest predictor of all-cause mortality — stronger than smoking, diabetes, or heart disease as individual risk factors. A landmark study in JAMA found that extreme fitness was associated with the lowest mortality with no upper limit of benefit. You can estimate VO2 max with a timed mile, a rower test, or a wearable. Get faster every year.

𝗡𝘂𝗺𝗯𝗲𝗿 𝗼𝗳 𝗠𝗲𝗱𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀
Target: as few as possible.
Every medication you're on should be earning its place. I just wrote about five commonly prescribed drugs that do more harm than good with long-term use. Bring your full medication list to every appointment. Ask: "Do I still need this?" Deprescribing is one of the most powerful and underused tools in medicine.
ꟷꟷꟷ

Thirteen numbers. Most available through cheap bloodwork and simple tests. Get them once or twice a year. Here's what I want you to understand: these numbers don't just tell you where you are. They tell you where you're heading. A fasting insulin of 8 today becomes diabetes in five years. An ApoB of 120 today becomes a heart attack in ten. An hs-CRP of 3 today means your arteries are inflamed right now — regardless of how healthy you feel. The standard annual physical checks a fraction of these. It was designed to find disease that's already there. This panel finds the disease that's coming — years before it arrives.

What gets measured gets improved. Optimize with the foundation I write about every week on this platform:
Zone 2 cardio plus resistance training 3-4 times per week. High-protein whole-food nutrition. Sleep 7-9 hours — non-negotiable. Morning sunlight. Stress management. And the targeted supplements I've covered in detail — creatine, magnesium, CoQ10, D3+K2, glycine, omega-3, psyllium husk.
The breakthroughs coming in the next decade — gene editing for cholesterol, cellular reprogramming, senolytics that clear senescent "zombie" cells driving inflammation and aging, GLP-1 drugs rewriting metabolic medicine — will be most powerful for people who've already built the metabolic foundation to receive them.

The future of medicine is personalized. But it starts with knowing your numbers today. Print this list. Book the bloodwork. Own the data. Prevention isn't passive. It's the most aggressive thing you can do for the decades ahead.

[Sport boy @Sp_bo1]

أخصائي علاج طبيعي امريكي :

تمارين للتخلص من حدبة الرقبة يمكنك إجراؤها يومياً في المنزل لتصحيح الانحناء

[Motivasyon @motivasyonhane]

Bu, dünyanın en çok işe yarayan esneme hareketi. Akıllı telefon boynu, kamburluk, düz boyun sorunu olanlar. Ve yüzde sarkma başlayanlar dahil.
Doğal olarak ve gerçekten düzeliyor, o yüzden kaslar sertleşince hemen yap.

[Hermine @Sainte_Hermine5]

Il est 3h du matin. Une douleur foudroyante vous arrache au sommeil : une crampe nocturne au mollet.

Ce n'est pas hasard. Votre corps vous envoie un signal de détresse bien précis qu'il faut absolument déchiffrer.

Quel est le vrai souci organique qui se cache derrière ? 🧵

[dr.zeynep 🩺 @dgrszlzynp]

Ünlü bir nörolog diyor ki:

Erken dönem demansın (bunamanın) ilk belirtisi unutkanlık değildir.

Herkes sanıyor ki demans önce hafıza kaybıyla başlar, ama gerçekte daha basit ve erken bir şeyle başlayabiliyor.

Bu işaret 45 yaş civarından itibaren fark edilebiliyor.

[Maikolll @MZora0419]

LA MAYORÍA DE LA GENTE CONOCE SU GRUPO SANGUÍNEO.

PERO POCOS SABEN LO QUE REALMENTE SIGNIFICA.

AQUÍ TIENES UNA EXPLICACIÓN SENCILLA:

- HILO 🧵

[María Isabel Fiallo Flor (Mamela)💙 @MamelaFialloFlo]

La selección de Croacia es la única 100% europea.
Son católicos. Fueron a misa antes de viajar.
Modric tiene una imagen de la Sagrada Familia en sus canilleras.
El entrenador reza el rosario durante los partidos.
¿Qué tal si lo damos a conocer al mundo?
Necesitamos más de esto.

[Lore Cárdenas. @LoreCardenasX]

El óxido nítrico te mantiene "vivo". Sin él, las erecciones fallan, el envejecimiento se acelera y el riesgo de infarto se triplica.

Aquí tienes 5 métodos científicamente probados para aumentarlo de forma natural:
1. No uses enjuague bucal.

[Alpha Prime @Alpha_Prime__]

High cortisol is the real reason you're insulin resistant.

If I wanted to reverse insulin resistance without medication, these are the 8 things I would do every day to fix it:

1. Delay your first meal (unless High protein)

[Shadow AP @AngelPerezxpx]

Conozca al médico número uno del mundo en el tratamiento de la grasa visceral.

Dr. Sean O'Mara.

Ha dedicado décadas a investigar cómo este asesino silencioso envenena nuestro cuerpo.

Estas son sus 7 reglas clave para eliminar la grasa visceral:

1. Coma más carne.

[Afshine Emrani MD FACC @afshineemrani]

1/5
I'm a cardiologist. I hear this in my office constantly:
"But my annual labs were always normal."
They're telling the truth. Their labs were normal.
But the standard blood panel has a fatal flaw — it was designed to find disease that's already there.
We wait for the house to catch fire. Then we try to put it out.
There are 8 tests that detect the frayed wiring years before the first spark. Most cost under $50. None are experimental. And they are completely missing from your annual physical.

[Miguel Ángel | GptZone @MiguelMaestroIA]

🚨 Guarda esta CLASE MAGISTRAL de 1 hora que he subtitulado al español.

Esta charla de "CÓMO HABLAR" ha sido una tradición del MIT durante más de 40 años.

Patrick Henry Winston creía que la forma en que nos comunicamos define nuestro éxito en la vida.

Pasó 50 años enseñando en el MIT y su legado trascendió las aulas e inspiró a miles de mentes brillantes.

Ofrecida cada mes de enero, tiene como objetivo mejorar la capacidad de hablar en situaciones críticas enseñándote algunas reglas heurísticas.

A pesar de ser un pionero de la Inteligencia Artificial, Winston descubrió que el éxito de los estudiantes de ingeniería no dependía solo de su capacidad técnica, sino de saber transmitir sus ideas.

- Prohibió empezar con un chiste porque el público aún no está adaptado al conferenciante. En su lugar, exigió abrir con una promesa clara de lo que la audiencia aprenderá.

- Una gran idea debe ser explicada de tres formas distintas a lo largo de la charla para asegurar su asimilación.

- Explicar detalladamente qué no abarca tu concepto para delimitar perfectamente su valor real y evitar confusiones.

- Jamás se debe leer el texto de las diapositivas, ya que las personas no pueden leer y escuchar con atención al mismo tiempo.

- Aprender a realizar preguntas y sostener un silencio de hasta 7 segundos para permitir que el cerebro de los oyentes procese la información.

Una masterclass para toda la vida.