Tailored perovskite-HTM interface prevents Li+ migration, unlocks scalability and improves the stability and performance of the final devices compared to the gold standard spiro-OMeTAD. Quite proud of this study! @AdvPortfolio 👨💻☀️
https://t.co/lbNJ1JONZ6
This isn’t a random scientist who got lucky.
Mariano Barbacid discovered the first human oncogene in 1982. He isolated H-RAS from bladder cancer cells and proved a single point mutation could trigger cancer. That finding launched the entire field of molecular oncology.
KRAS mutations cause 90% of pancreatic cancers. For 43 years, oncologists called KRAS “undruggable” because the protein had no obvious binding pocket. Barbacid spent the last decade using genetically engineered mice to systematically test every node in the KRAS signaling pathway, looking for combinations that would work without killing the patient.
The triple therapy blocks KRAS three ways at once: the main growth signal, the escape routes through EGFR and HER2, and the stress-response backup through STAT3. Cut the engine, seal the exits, disable the emergency system. Tumors vanished in mice and didn’t return for 200+ days after treatment stopped.
Pancreatic cancer has a 13% five-year survival rate. 8% for the ductal adenocarcinoma type this therapy targets. Most patients live one year after diagnosis.
The catch: this is preclinical. Human trials are 3+ years away. One of the drugs, RMC-6236, might get approved this year, but the full triple combination has regulatory hurdles.
Still. The man who discovered human oncogenes in 1982 may have just figured out how to eliminate the cancer those genes cause. That’s a 43-year arc from first principles to potential cure. Science rarely works this clean.
📢ICMol researchers among the world’s top 2% most cited scientists 📷
Several researchers from the Institute of Molecular Science (ICMol) at the University of Valencia are listed among the top 2% most cited scientists worldwide, according to the 2025 update of Stanford University’s World Ranking of Scientists. The list includes: Henk Bolink; Joaquín Calbo, Eugenio Coronado Miralles; Ferrando-Soria, Jesùs; Gaspar, Ana Belén; Carlos Martí-Gastaldo; Mínguez Espallargas, G.; Pardo, Emilio; Real, José Antonio.
📢 This month we already have 3 #ICMolTalks scheduled, You are all invited!
Check out these talks and all our upcoming events in our agenda 👉https://t.co/0HjUcwZYVZ
A very productive week! Interested in a quantum chemical descriptor to pre-screen INVEST TADF properties? Check Youssef's preprint! https://t.co/NE2OlfLf2q
📢Job offer: PhD position (FPI) at @ICMol_UV (Profs. Profs. Juan Aragó and Joaquín Calbo). Project: "Computational Modelling of Complex Systems for Energy and Sustainability". More information and application: https://t.co/iQgNlqAWu6
Interested in modeling complex excited state properties of TADF materials? Check the new contribution from my PhD student Steven He ! #proudPI#computationalchemistry#photochemistry https://t.co/yeoSycQEvs
Group picture on the last day of the 25th Anniversary Workshop of the TCCM Master #TCCM25th ⚗️💻
Congratulations to the organisers and big thanks to all the participants for coming to Donostia-San Sebastián 👏👏👏👏
@uik_eus@upvehu@ehu_kimika@DIPCehu@RSEQUIMICA
Excited to share the latest collaborations from the MolMatTC group, in which I’ve had the pleasure to participate!
https://t.co/vOE2HKRhXc...
https://t.co/ZajDY273ea
https://t.co/wd8a0ifb1c
Last week I was very lucky that I could attend #WATOC2025. I contributed with a poster about our work on the charge transport properties of hole transporting materials at @ICMol_UV ☀️⚡️
Great success at the XL Biennial Meeting of the Spanish Royal Society of Chemistry (RSEQ) in Bilbao! Preparations are already underway for the XLI Biennial Meeting in Murcia, 2027!🔬 #RSEQ#Chemistry
ICMol is accredited for the third consecutive time as a María de Maeztu Unit of Excellence in the provisional resolution of the AEI.
We’re proud of the incredible work and dedication of the 300+ people who make up our institute. Together, we keep pushing the frontiers of molecular science!
ℹ️More Information: https://t.co/239pUck8yy
#ICMol #Nanoscience #WeAreICMol ph:UB
Felicitaciones Dra. María Esteve Rochina! Muy buena la defensa y un gran placer compartir con Enrique Ortí, Joaquín Calbo y los otros jurados en la preciosa Valencia. Gracias por la invitación y la hospitalidad! @MEsteveRochina@ICMol_UV@UV_EG
📢📢Interested in transition metal complexes' photophysics? PhD opening at @LudoTroian 's lab (UCL, Louvain-la-Neuve) and at my lab (KU Leuven). Please RT
🎉 Congratulations to Miriam Navarrete Miguel from the QCEXVAL group on successfully defending her PhD thesis: “Photophysical and photochemical mechanisms of DNA damage and repair” 🔬✨
Supervised by Dr. Daniel Roca Sanjuán (ICMol-UV) & Dr. Virginie Lhiaubet-Vallet (CSIC-UPV).
#WeAreICMol #PhDDefense 🎓👏
Aunque a veces se olvide que existimos, hay muchas mujeres haciendo ciencia y como, nunca está de más recordarlo, estoy organizando una exposición artística para destacar la investigación científica de algunas de ellas
Así que si estás por Madrid no dudes en pasarte a verla!