Marc Goudge

Postdoc in @Bahmanyarlab @MCDB_Yale. PhD from Paszek Lab @CornellBME. I like organelles.

[Marc Goudge @MarcCGoudge]

@SangwooSPark @DamonRunyon Woohoo! Can’t think of a more deserving person :)

[Marc Goudge @MarcCGoudge]

Microscopy twitter! Has anyone had a chance to use CATCHFIRE yet? Looks incredibly promising from the size and reversibility, but I've been burned before buying specialized, expensive reagents.

[Marc Goudge @MarcCGoudge]

@JasonCMarvin @Matt_AWhit We were such babies 👶

[Marc Goudge @MarcCGoudge]

This Thursday (5/25) @ 9:00 AM EST, I'll be defending my PhD! If you want to learn about how Muc1 can regulate intracellular membrane morphologies and more, all are welcome! The event will be hybrid, so please DM if interested. Some fun highlights that didn't make the talk:

[Weill Institute for Cell & Molecular Biology @weillinstitute]

It’s molecular and cell biology group time!! 🍕🍺🔬🧬

Today: Marc Goudge and Misha Kazi from the Paszek lab @CornellEng & @DoerrLab @CornellMicrobio respectively!

[Marc Goudge @MarcCGoudge]

Did you think the Paszek group's work on mucin curvature generation at the plasma membrane was interesting? Ever wondered what these transmembrane mucins could be doing on their way to the cell surface? Come find me Dec 5th at #cellbio2022!

[Marc Goudge @MarcCGoudge]

Have people had a chance to play around with StayGold yet? The KDEL-tagged version looked pretty promising for SIM based applications regardless of the dimerization, but haven't seen any additional reports of its use yet.

[Cell Biology J-Club @cell_club]

Membrane curvature regulates the spatial distribution of bulky glycoproteins | Nature Communications https://t.co/5G1HdqbwvU

[Marc Goudge @MarcCGoudge]

@dwmckellar @DeVlaminckLab @bdcosgrove !!!!! Congrats, very exciting

[Marc Goudge @MarcCGoudge]

@hankgreen In a*

[Marc Goudge @MarcCGoudge]

@hankgreen Hi! I'm just finishing up a PhD a mucin lab.

[Marc Goudge @MarcCGoudge]

For those who have used the RUSH system - does anyone have any reference as to where to get your hand on lentiviral variants? Or has everyone just been making their own in house if need be?

[Marc Goudge @MarcCGoudge]

@abhishekshwarma Very fortunate that research lets me use google because otherwise I'd be screwed.

[Marc Goudge @MarcCGoudge]

@PhunsizeDPhD @BEAMvt Woah! Congrats, that's amazing news Monet!

[Marc Goudge @MarcCGoudge]

Steven's great work is now available as a preprint! Just a massive effort by him to detail how glycocalyx thickness acts as a regulator of immune-cell induced cytotoxicity.

[bioRxiv @biorxivpreprint]

Mucins form a nanoscale material barrier against immune cell attack https://t.co/1E5hB6Pqwk #bioRxiv

[Marc Goudge @MarcCGoudge]

@MoniIntheBank ?? STOP EATING IT

[Marc Goudge @MarcCGoudge]

@abhishekshwarma If only, my heuristic was quite poor (start at max distance radially and try and come to the middle)

[Marc Goudge @MarcCGoudge]

Found a real life application of this problem today, not just imsge processing!

[Marc Goudge @MarcCGoudge]

A hacky, not entirely accurate solution - doing k-means clustering. Looks pretty alright!

[Marc Goudge @MarcCGoudge]

Cell or Wreath?