Mariah

happy, high energy optimist. we should build more.

[Mariah @mariah__nel]

Well it also mostly didn’t — the data that did come out was that the device regularly failed their own internal accuracy benchmarks. Maybe eventually they could’ve gotten it to work (which would have been /would be awesome), but that’s not how medical device regulation works. You don’t get to lie to people about what the device is currently capable of and then try to catch up

[Mariah @mariah__nel]

Weird watching people leave the Holmes movie newly unsure she did anything wrong. The film strangely never mentions that Theranos’ machine ran only ~12 of 200+ offered tests and the rest were secretly diluted and run on other company's machines. Or that Theranos destroyed the only decryption key to its lab database 3 mo after a grand jury subpoenaed it. Charisma isn’t exculpatory.

[Mariah @mariah__nel]

There was no new evidence presented. It's strange to be asked to reassess Holmes' guilt based on her vibes.

Also don’t get the film’s fixation on whether they got paid. Turning down money only means something before the cameras roll. Giving it up after shooting seems kind of meaningless? (unless you're A24)

[Mariah @mariah__nel]

@ArtirKel for if you wanna just flip through them on your phone https://t.co/bcnn3HhTBf

[Mariah @mariah__nel]

These would make for much better SF conversation starters than askhole.

Here are the consolidated qs from 2009-2025. If some fund makes glossy party gift cards of these, I would like a set.

https://t.co/kAxrxiHcJB

[Sid @mosasaurus27]

As a freshman going to a mixer, I remember keeping some of the all souls exam questions in mind because they genuinely make great conversation beyond the standard “what’s your name, what course do you study”

One of my favorite ones was: Does the morality of an orgy change if all participants are wearing Nazi uniforms. I asked this on one of the early dates with my partner of 4-years. Don’t know if this helped my case but it was an entertaining discussion

[Sam D'Amico @sdamico]

Should have a state law where if vacancy drops below 5%, we legalize constructing anything that passes fire code

[Mariah @mariah__nel]

Reminds me of some the stories in Albiek's Biohazard (about the bioweapons program in the USSR) ☣️

Like when a maintenance vent wasn’t properly replaced so anthrax spores blew into the nearby city killing 60+. And the KGB blamed black market meat and destroyed all hospital records and the incident wasn’t acknowledged until the 90s.

Or when they were open-air testing smallpox distribution on an island and a deckhand on a passing ship got it and brought it home. And it took decades to find out her home city had been sealed off and ~50,000 people had been vaccinated.

Or when, after he defected, he told the US that soviet scientists had been working on antibiotic resistant plague.

[Kevin Esvelt @kesvelt]

Russian authorities have surely sequenced the Irkutsk pathogen, but refuse to identify it.

Physical lockdown indicates it cannot be controlled with prophylactic antibiotics, implying engineered pan-resistance or that it isn't plague at all.

2/4

[Mariah @mariah__nel]

@daradoescode Also how people view tesla self driving (if they tried auto pilot in older cars)

[Mariah @mariah__nel]

Post GLP CPG

[Mariah @mariah__nel]

@teo_kai_xiang I wonder what the appetite for arranged marriages is among the cohort using this service

[Mariah @mariah__nel]

@GrantSlatton @GetRowZero @databricks Congrats!!! 🎉

[Mariah @mariah__nel]

1. that doesn't change the ask: which is make the process more legible to make it easier to improve upon

Dr Fajgenbaum's work -- using ML to compare thousands of drugs and diseases -- is done out of his non-profit. Based on the article it seems he'd be excited for other people to contribute and save/improve more lives faster.

2. I don't follow your 'specialized tool only academics can access' argument. Even if it were the case that the tool here is gated, researchers reading the article don't magically know which tool, model, or features were used simply by being part of a university. If the goal is saving more lives faster, there seems to only be upside to publishing the prompts, model, and process. E.g. with models improving this fast, a documented process lets anyone rerun it on a newer model and see if it does better; or more people learn the systems exist and can use it.

[Mariah @mariah__nel]

@tzmartin @InstituteCicero It would be really awesome if stories like this started to include the prompts, models, and process the team used for diagnosis.

[Mariah @mariah__nel]

Haven’t driven a Tesla for a while and *holy wow* is full self driving excellent.

It did 99% of my driving this weekend (including pulling into and out of parking spots).

[Mariah @mariah__nel]

This applies to some grad programs too. E.g from an acquisition of knowledge and useful experience perspective, there’s no reason law school should be 3 yrs.

Do Barbri upfront to learn the black letter law, then 1-2 years of coursework and apprenticeship to understand interpretation/legal theory and how the law works in practice

[Mariah @mariah__nel]

@GrantSlatton it’s a knock off of this https://t.co/0Q8BOjk1NV

[M. Nolan Gray 🥑 @mnolangray]

A 25% jump in rents year over year should be a five-alarm fire, the sort of thing that happens after a natural disaster and should motivate a bunch of emergency measures to get housing built ASAP, but it's business as usual in San Francisco these days. That's a huge problem.

[Mariah @mariah__nel]

Sad realization: ugliest sneakers (Hokas) are the most comfortable (akin to walking on fluffy clouds).

[Mariah @mariah__nel]

It’s great to see signs of high conscientiousness in society. People have been told to dispose of used needles in sharps containers and they’re trying to do the right thing.

The problem is we make sharps disposal super challenging — the pharmacy and drs won’t take back needles for disposal and most disposal sites (when actually still open and maintained) are in the middle of junkie wastelands

[Alexa @iamgiardiniera]

Nordstrom Rack restroom btw lmao

[Mariah @mariah__nel]

@MWCvitkovic Good god, I hope this is real