Mario Barilani, PhD

Advanced therapies expert & Biomedical scientific officer
—
Rare genetic diseases ~ R&D funding policy ~ Regenerative medicine ~ Gene therapy ~ Stem cells

[Mario Barilani, PhD @mario_phd]

During #MassivEV #ISEV workshop Quality-by-Design was introduced. Even though more useful at late phases, development of #EV therapeutics may also benefit.
This is our take on the #upstream phase using human induced pluripotent stem cells.

#QbD #hiPSC

https://t.co/By27NTuGMp

[Mario Barilani, PhD @mario_phd]

#massiveEV #isev workshop was so informative and challenging at the same time. Really massive thank you to the EV unit for the massive work that lead our research to this point!

[Bhagyashree Joshi @BSJOSHI_]

Very excited to share my very first review article as a co-corresponding author! This is a comprehensive review on using #ExtracellularVesicles as therapeutic vehicles & we share our vision for further development in the EV field
https://t.co/HCE3eIuZH6 @MaterialsToday @IsevOrg

[Eni Kostallari @EKostallari_PhD]

I got this 🥠 message a few years back, when I just started my postdoc @MayoClinicGIHep. I was hopeless and depressed. This gave me hope. And it made me understand that success has no taste without failure. Failure + perseverance = progress = success. @jenheemstra

[Mario Barilani, PhD @mario_phd]

@KennethWWitwer It's this spontaneous tendency toward dogmatic interpretation of indications...

[Kenneth W Witwer (he/him) @KennethWWitwer]

Next #EVClub: #iPSC #ExtracellularVesicles and #hematopoiesis w/Ewa Zuba Surma & Ela Karnas
September 29, 12 noon (EDT)/18.00 (CEST)/Midnight (Beijing)
Paper in Leukemia, 2021: https://t.co/C3MboldJXl
Need the login? Sign up here: https://t.co/9sKDU3LKOe
@IsevOrg @IsevComms

[Mario Barilani, PhD @mario_phd]

Just back home after participating to two in-person conferences in a row on #extracellularvesicles @EVItaSociety and #celltherapy #stemnet
Mind- and soul-blowing realizing how much I missed this aspect of science. A boost of passion and motivation!

[EVIta- Italian Society for Extracellular Vesicles @EVItaSociety]

Second day of EVIta symposium started with an insightful presentation on MSC EVs by @BGiebel followed by great talks of EVItians! It is impressive how high impact research has advanced in these last 2 years!🤩

[Benedetta Bussolati @BBussolati]

Curious about tetraspanin expression in small and medium/large mesenchymal stromal cell-derived extracellular vesicles in naive or apoptotic condition? have a look! https://t.co/tGty0IxBK2 #bioRxiv

[Retraction Watch @RetractionWatch]

"Reproducibility: expect less of the scientific paper."
https://t.co/lomgv1P19i

[Kenneth W Witwer (he/him) @KennethWWitwer]

The recording is up! If you missed the @IsevOrg/#SOCRATES #EVClub with Sai Kiang Lim, you can now watch the session on YouTube: https://t.co/4TaGgLklcQ #ExtracellularVesicles #MSCs #MSCEVs #therapeutics #nanomedicine #MISEV

[Mario Barilani, PhD @mario_phd]

This new trend by some (many?) scientific journals to reject a paper that's undergone #peerreview, without sharing reviewers' comments while proposing a transfer to the IF-less unindexed sister journal... IT'S THE WORST! Not playing this game...

[ISEV @IsevOrg]

Are you ready for an in-person meeting? ISEV is! massivEVs is a Workshop all about producing large amounts of #ExtracellularVesicles. 28-29 Oct in Brescia, Italy. Apply by 11:59 PM EDT on June 1st if interested: https://t.co/YcSrcrpK3X

[Mario Barilani, PhD @mario_phd]

@IsevOrg Submitted my abstract today, but didn't receive any feedback by email. Do I have to worry?

[Mario Barilani, PhD @mario_phd]

Attending #ISEV2021 one month before the kick-off of our #NANO4STROKE @euronanomed funded project was the perfect motivational boost and the perfect timing. Looking forward to starting the development of large-scale processes for EV production! #extracellularvesicle #nanomedicine

[Mario Barilani, PhD @mario_phd]

@tomdriedonks your presentation closed the meeting with fireworks! Really relevant and compelling #ISEV2021

[Mario Barilani, PhD @mario_phd]

Going through #ISCT #ISEV2021 joint session on Rigor and Regulation of EV therapeutics, I would have appreciated also EMA contribution. Still, the core principles don't change, and I feel lucky to be already familiar with them thanks to my GMP colleagues!

[Mario Barilani, PhD @mario_phd]

Day 2 of #ISEV2021 and already finished my notepaper, too many useful experimental perspectives, technical tips and thrilling insights to handle

[Mario Barilani, PhD @mario_phd]

@KennethWWitwer I lost it, will it be available offline tomorrow? Hope so! Thanks!

[Mario Barilani, PhD @mario_phd]

Moving from characterization of EV to functional studies may feel like entering Alice in Wonderland's rabbit hole. Expect the unexpected.