Macklemore says Ed Sheeran and his team decided to remove him from tour due to his comments in support of Palestine, after Kraft Group rallied stadium owners and gave Ed an ultimatum:
“[Ed] told me that the words ‘Free Palestine’ and the image of the Palestinian flag were hurtful to a lot of people he spoke with. I told him that if those words were more offensive than tens of thousands of Palestinian children being killed by Israel, then there was a fundamental disconnect between where those people stood and where I stood. But he couldn't get past his public facing, ‘I don't take sides.’”
amo que o jack antonoff deve estar indo com um gravador no bolso pra gravar os aplausos dos convidados na cerimônia pra taylor poder implementar em alguma música do TS13 sobre o casamento
Josh Dun and Tyler Joseph of Twenty One Pilots say they're both Swifties, and that Dun's wife, Debby Ryan, discovered that "Enchanted" is the one song that calms their baby down. #AMAs
A psychiatrist named Jan Fawcett tracked 954 depressed patients. He found that one symptom predicted who would die by suicide within a year, no matter how bad their depression was otherwise: losing interest in everything. Doctors call it anhedonia.
It shows up on brain scans. A small region deep in the brain called the reward center quietly stops working, and the brain releases less dopamine, the chemical that makes things feel good. Around 70 percent of people diagnosed with major depression report this loss of interest. A 2024 review in the International Journal of Neuropsychopharmacology found that patients with anhedonia are much more likely to end up with depression that doesn't respond to medication.
The most prescribed antidepressants often fall short on anhedonia. SSRIs like Prozac, Zoloft, and Lexapro mainly raise serotonin, but anhedonia is mostly a dopamine problem, so the standard prescription is aimed at the wrong chemical.
Four treatments have actual evidence. Ketamine, and a nasal spray version called esketamine approved for stubborn depression, can lift anhedonia in hours. Standard antidepressants take weeks. A 2025 paper in the journal Neuron traced this to specific changes inside the brain's reward center. Behavioral activation therapy, where patients schedule small pleasurable activities and force themselves to do them even when they don't feel like it, slowly teaches the reward center to fire again. Exercise releases a brain-repair protein called BDNF that helps rebuild dopamine pathways over weeks. And a treatment called TMS, which uses magnetic pulses on the front of the brain, has shown strong results in recent trials for anhedonia specifically.
There is also a newer research area called digital anhedonia. Brain scans of heavy social media users show the reward center lights up strongly for notifications and feeds but stays quiet for ordinary pleasures like food, conversations, and walks. The reward bar gets reset so high that normal life cannot reach it.
The brain heals. With proper treatment, many people improve within weeks, and the reward system can rebuild over months. So losing interest in everything is treatable. And the first medication doctors usually prescribe is rarely the one that fixes it.