Family Physician and Professor of Epidemiology at the University of Georgia. Editor-in-chief of Essential Evidence, Deputy Editor of American Family Physician.
Using that calculator, the NNT to prevent one hospitalization is 1148 for low risk patients (two-thirds of all patients), 84 for moderate risk and only 20 for high risk. Our Paxlovid study is in J Gen Intern Med: https://t.co/EmhPuNGE0d
Our latest study shows that Paxlovid continues to be associated with a significant reduction in mortality (RR 0.43) and hospitalization (0.45). With 0.7% hospitalization rate currently, NNT~250, but lower for higher risk patients. https://t.co/EmhPuNGE0d
You can pair this with our previous studies validating a simple 3 item risk score for outpatients with COVID (age, dyspnea and comorbidities) that you can find for free as a calculator here: https://t.co/RDdBqe6GFi
Pleased to share our new study, a prospective external validation of pneumonia risk scores in US primary care. The 2 best were from the European GRACE study. Learn more! #NAPCRG#STFM#EJGP#WONCA https://t.co/IaovpC1zPW