Mark Hofmeyer

AHF/Tx Cardiologist, Assc Professor @GUMedicine, PD of AHFTC Fellowship, Med Dir AHF-IMC @MedStarWHC, Former @UMJMHCardiology @WayneMedicine @UMich

[JACC Journals @JACCJournals]

Selective in vitro enhancement of cardiac myosin motor function and myofilament force generation by danicamtiv prompted clinical evaluation. A short course of danicamtiv was generally well tolerated in participants with #DCM. https://t.co/OS5zxv1hLT

#HFSA2025 #JACC #cvGenetics

[Eiran Gorodeski, MD, MPH @EiranGorodeski]

Here are all AHFTC fellowship programs that offered spots in last 5 years, and # of fellows they matched. 13 programs trained 50% of fellows. #HFSA2025 Skewed uneven distribution. Mega centers train most of the field. Insufficient exposure to community and rural needs. Worrisome.

[Mark Hofmeyer @MarkHofmeyer]

@UMJMHCardiology @GeneticCardiomy @CircAHA @DCMProject @RayHershberger @gordonshuggins @eksjordan @greg_ewald @amorrismd @tikuowens @WilsonTangMD @bhtrachtenberg @PalakShahMD @DrNancySweitzer @MWheelerMD @WilcoxHeart @stephenpanmd @UMiamiHealth @JacksonHealth @russcolombomd Thanks, Russ! Would love to!

[Mark Hofmeyer @MarkHofmeyer]

>25% of patients w/severe DCM have P/LP variants @GeneticCardiomy (OR 2.3) Thanks @CircAHA @DCMProject @RayHershberger @gordonshuggins @eksjordan @greg_ewald @amorrismd @tikuowens @WilsonTangMD @bhtrachtenberg @PalakShahMD @DrNancySweitzer @MWheelerMD @WilcoxHeart @stephenpanmd

[MedStar Washington @MedStarWHC]

A new study led by Dr. @MarkHofmeyer and fellow researchers from across the country have demonstrated the benefits of routine #genetictesting for patients with advanced #heartdisease from dilated cardiomyopathy and their at-risk family members. Learn more: https://t.co/Nqs6I79hW0

[Mark Hofmeyer @MarkHofmeyer]

We're recruiting for AHFTC Fellowship at MedStar- Georgetown. 47 OHT/65 LVAD FY2024. Nationally recognized Infiltrative CMP Program, PH, shock team, cardiogenetics. @MrinaliniKrish2 @fsheikh22 @PhilLamMd @AfariArmahN @RichaGuptaMD @miguelpinillav https://t.co/VT0dpXDiVv

[Mark Hofmeyer @MarkHofmeyer]

Excited that our work was one of the Editor-in-Chief’s Top Picks From 2023! @JACCJournals

[Mark Hofmeyer @MarkHofmeyer]

On clinical screening, 1 in 7 FDRs of patients c/DCM have newly diagnosed DCM or partial DCM phenotype @DCMProject @RayHershberger @gordonshuggins @eksjordan @greg_ewald @amorrismd @tikuowens @WilsonTangMD @bhtrachtenberg @PalakShahMD @DrNancySweitzer @MWheelerMD @WilcoxHeart

[American College of Cardiology @ACCinTouch]

What is the value of clinical screening among reportedly unaffected first-degree relatives of patients (probands) with dilated cardiomyopathy?

Get the answer & read more in #JACC: https://t.co/i5wW4HH8mI #cvGenetics

[Mark Hofmeyer @MarkHofmeyer]

A tour de force @maferradastrong https://t.co/R5yZMAsuEN

[DCMFoundation @DCM_Foundation]

Close to 50% of DCM cases have an unknown cause, but there is growing evidence that most of these cases are genetic. Learn more about the genetics of DCM: https://t.co/Y8ASVAvRnG

[Steve Pan @stephenpanmd]

“And another one!” @ShazliKhanMD now presenting TWO cases of ARVC initially felt to be COVID-19 related myocarditis, demonstrating the role of genetic testing in cardiomyopathy diagnosis. #hfsa2023 @WMCCardsFellows @WestchesterMed @nymedcollege

[Mark Hofmeyer @MarkHofmeyer]

In two weeks - Join me and my co-director @fsheikh22 in Washington, DC, for @Medstar 6th Annual Advanced Heart Failure Summit! Keynote: @MRMehraMD @fsheikh22

Register Now:  https://t.co/qrdHGbEy0L

[Mark Hofmeyer @MarkHofmeyer]

@CyrusHadadiMD @fsheikh22 @MRMehraMD @medstar @AfariArmahN @cjbither @RaniaKaoukis @PhilLamMD @miguelpinillav So excited to hear your talk!

[Mark Hofmeyer @MarkHofmeyer]

10/21/2023 - Register now - @fsheikh22 and I are excited to be back in person this year with @MRMehraMD for our annual @Medstar Advanced Heart Failure Summit. @AfariArmahN @cjbither @CyrusHadadiMD @RaniaKaoukis @PhilLamMD @miguelpinillav

https://t.co/jHiICcfYIT

[Mark Hofmeyer @MarkHofmeyer]

@MedStarWHC @CircAHA Thanks to @lamcardio @CircAHA on the Run @RayHershberger for inviting me to discuss the work of the @DCMProject. Patients & FDRs need phenotypic & genotyping screening to better characterize, intervene earlier, and develop precision medicine therapies for DCM.

[Mark Hofmeyer @MarkHofmeyer]

@mohilgarg13 @fsheikh22 @PhilLamMD @RichaGuptaMD @miguelpinillav @GTCardFellows @IMMWHC Looking forward to seeing you there!

[Mark Hofmeyer @MarkHofmeyer]

@DmitryAbramovMD Thanks! Stay tuned for more from the DCM Consortium!

[Mark Hofmeyer @MarkHofmeyer]

https://t.co/yTp0msu5GU

[JAMA @JAMA_current]

Assumptions regarding dilated cardiomyopathy genetic architecture derived from European ancestry may not apply to African ancestry; a current lack of case data limits clinical genetics care for patients of African ancestry with dilated cardiomyopathy. https://t.co/LNrxrECfDt

[Nosheen Reza, MD, MS @noshreza]

New from DCM Precision Medicine Study in @JAMA_current:

Genetic Architecture of Dilated Cardiomyopathy in African and European Ancestry

⬇️pts of African (8.2%) than of European ancestry (25.5%) had variants classified as pathogenic/likely pathogenic

https://t.co/3oniXmxrfI

[Mark Hofmeyer @MarkHofmeyer]

An amazing podcast with an amazing superhuman!@maferradastrong
https://t.co/bsbbAkD5Yo