Selective in vitro enhancement of cardiac myosin motor function and myofilament force generation by danicamtiv prompted clinical evaluation. A short course of danicamtiv was generally well tolerated in participants with #DCM. https://t.co/OS5zxv1hLT
#HFSA2025#JACC#cvGenetics
Here are all AHFTC fellowship programs that offered spots in last 5 years, and # of fellows they matched. 13 programs trained 50% of fellows. #HFSA2025 Skewed uneven distribution. Mega centers train most of the field. Insufficient exposure to community and rural needs. Worrisome.
A new study led by Dr. @MarkHofmeyer and fellow researchers from across the country have demonstrated the benefits of routine #genetictesting for patients with advanced #heartdisease from dilated cardiomyopathy and their at-risk family members. Learn more: https://t.co/Nqs6I79hW0
What is the value of clinical screening among reportedly unaffected first-degree relatives of patients (probands) with dilated cardiomyopathy?
Get the answer & read more in #JACC: https://t.co/i5wW4HH8mI #cvGenetics
Close to 50% of DCM cases have an unknown cause, but there is growing evidence that most of these cases are genetic. Learn more about the genetics of DCM: https://t.co/Y8ASVAvRnG
“And another one!” @ShazliKhanMD now presenting TWO cases of ARVC initially felt to be COVID-19 related myocarditis, demonstrating the role of genetic testing in cardiomyopathy diagnosis. #hfsa2023@WMCCardsFellows @WestchesterMed @nymedcollege
In two weeks - Join me and my co-director @fsheikh22 in Washington, DC, for @Medstar 6th Annual Advanced Heart Failure Summit! Keynote: @MRMehraMD @fsheikh22
Register Now: https://t.co/qrdHGbEy0L
@MedStarWHC@CircAHA Thanks to @lamcardio@CircAHA on the Run @RayHershberger for inviting me to discuss the work of the @DCMProject. Patients & FDRs need phenotypic & genotyping screening to better characterize, intervene earlier, and develop precision medicine therapies for DCM.
Assumptions regarding dilated cardiomyopathy genetic architecture derived from European ancestry may not apply to African ancestry; a current lack of case data limits clinical genetics care for patients of African ancestry with dilated cardiomyopathy. https://t.co/LNrxrECfDt
New from DCM Precision Medicine Study in @JAMA_current:
Genetic Architecture of Dilated Cardiomyopathy in African and European Ancestry
⬇️pts of African (8.2%) than of European ancestry (25.5%) had variants classified as pathogenic/likely pathogenic
https://t.co/3oniXmxrfI