I am excited to share an updated preprint from my PhD work with @lisa_giocomo! This project was co-led by @KaganovskyNeuro when he was a PhD student with Tom Südhof. 🧵below!
Hippocampal place code plasticity in CA1 requires postsynaptic membrane fusion https://t.co/4KGSMjfS6L
I’m excited to share my first preprint, with @john_widloski and @replayprof! We find that self-avoidance dominates the selection of hippocampal replay.
https://t.co/uVuSNyOetu
#tweeprint below!
I'm excited to share a preprint reflecting my PhD work with @lisa_giocomo, where we characterized the impact of aging on the medial entorhinal cortex (MEC), a key hub of spatial coding and memory. 🧵below!
https://t.co/XYULR1Zb5m (1/11)
Stay tuned for an updated preprint from @KaganovskyNeuro that digs into the in vitro characterization of Stx3-dependent plasticity as well as a slew of Stx3-dependent (and independent) behaviors!
I am excited to share an updated preprint from my PhD work with @lisa_giocomo! This project was co-led by @KaganovskyNeuro when he was a PhD student with Tom Südhof. 🧵below!
Hippocampal place code plasticity in CA1 requires postsynaptic membrane fusion https://t.co/4KGSMjfS6L
We also found that CA1 Stx3 is necessary for expressing in vivo correlates of behavioral timescale plasticity and for plasticity associated with putative sharp wave ripples. This means Stx3-dependent membrane fusion may be a common molecular mechanism for these processes!
The ACR lab will be opening soon @DukeU! We are looking for curious biologists, computer scientists, and neuroscientists to study how the brain "turns on" during development. More info here 👉 https://t.co/r2PSX8TAoo
It was an immense pleasure to join the ASAP crew & @MichaelLinLab for this project! ASAP4 is an awesome tool for the community!
Congrats to all of the authors!
Today in @naturemethods: our new positively tuned voltage indicator, ASAP4e, for extended electrical recordings in the brain.
ASAP4e achieves greater responsivity (>200% per 100mV vs 50% for other fluorescent voltage sensors) and better photostability.
https://t.co/wOq1fAtx5h