Interesting observation in @NatureCancer: only 60% of hematological patients with #COVID19 receiving anti-CD20 antibody therapy and stem cell transplant developed #SARSCoV2 antibodies. Prior #COVID19 in high risk subgroups does not guarantee immmunizaton!
https://t.co/RuNxqUaiOi
@ASTCT@ASTCT_Journal Platelet refractoriness itself is a marker of severe SOS. We’ve had some transient increments with HLA matched platelets in patients where this preceded diagnosis of SOS but very hard to maintain arbitrary Plt>XX
Massey Cancer Center and our Cellular Immunotherapy and Transplant Program treats many historically underserved patients needing transplantation, it was great to participate in this study to expand access to a broader population otherwise not reached with curative intent!
@Amir_Ahmed_Toor Agree these are the policies we are following according to the Seattle experience. Balancing risk and benefit; individual patient risks also being weighed.
Tweet 2 of 6: #Tweetorial 25-30% of patients with AML will have a FLT3 mutation (including TKD and ITD), so #FLT3 mutations are common; not only common but important for prognostics as FLT3-ITD mutation carries a worse prognosis in patients with diploid cytogenetics
| #leusm
An updated set of CAR-T resource slides are now available to members and non-members! Everything from the basics of immunology to managing neurotoxicity in CAR-T patients. https://t.co/ugRzd4y9dM
Nice review on how to chose donors for haploHCT by @Haplo_Doc@TheEBMT consensus recommendations for donor selection in HaploHCT : Check for DSA, choose younger donors , male donor for male recipient, offspring or sibling donor over parent donor
https://t.co/QOtrLRhDTK
Standard ATG Dosing Results in Poorer Outcomes in Overexposed Patients after Ex vivo CD34+ Selected Allogeneic Hematopoietic Cell Transplantation https://t.co/8rgzD3flal