Jeffrey West

Christian, mathematician, reader, 🇺🇸. Assistant Prof at @MoffittNews: #MathOnco, cancer evolution, antifragility, cellular automata, #sciart

[Jeffrey West @mathoncbro]

Our "evolutionary antifragile therapy" paper is now posted online (Cancer Research):
https://t.co/QyGexLImV2

First experimental validation of antifragility in cancer (ALK inhibitors in lung)! An awesome collaboration involving @ara_anderson, @AndriyMarusyk, @Binadesai14 et al

[Jeffrey West @mathoncbro]

Our "evolutionary antifragile therapy" paper is now posted online (Cancer Research):
https://t.co/QyGexLImV2

First experimental validation of antifragility in cancer (ALK inhibitors in lung)! An awesome collaboration involving @ara_anderson, @AndriyMarusyk, @Binadesai14 et al

[Max Unfried @MaxUnfried]

Interested in Entropy & Aging?

Note that there will be an Entropy in Aging conference and workshop in Cologne end of August, enabled by the International Aging Entropy Open Research Network!

Attendance is free of charge and focused on intimate discussions!

https://t.co/fTfC0DKo3t

@Meyer_DH

[Jeffrey West @mathoncbro]

@DannGuerreroR @ASTRAZENECAUK @CellRepMethods Very very cool! Congrats Daniel!

[Daniel Guerrero-Romero 🏳️‍🌈🇲🇽 @DannGuerreroR]

Caldas' Lab paper out together with @ASTRAZENECAUK in CRM:"Real-time cell viability monitoring for high-throughput drug screening using tumor xenograft-derived cells" @CellRepMethods
https://t.co/sFVqRRZX4z
We screened 67 compounds × 43 breast cancer PDTCs (1,117 drug–model combos) but the first story we want to share here is how we measured response.

[Cancer Research @CR_AACR]

ICYMI—the December 15 issue received the most votes in our cover contest! Congrats to the authors of "Mathematical Oncology: How Modeling Is Transforming Clinical Decision-Making." https://t.co/TEx0Acyhea
@ara_anderson @mathoncbro @sandhya212 @MoffittNews #MathOnco

[Jeffrey West @mathoncbro]

@nntaleb, your ideas at work in experimental settings. Next up, clinical translation...

[Jeffrey West @mathoncbro]

Our "evolutionary antifragile therapy" paper is now posted online (Cancer Research):
https://t.co/QyGexLImV2

First experimental validation of antifragility in cancer (ALK inhibitors in lung)! An awesome collaboration involving @ara_anderson, @AndriyMarusyk, @Binadesai14 et al

[Jeffrey West @mathoncbro]

We think of antifragile therapy as a class of "evolutionary therapy" and that it represents a path forward for designing adaptive dosing protocols in the future.

[Jeffrey West @mathoncbro]

Switching between continuous and varied dosing (intermittent) represents the best of both worlds: kill tumor, avoid resistance.

[Tampa Bay Lightning @TBLightning]

After his dad passed from cancer in March, Raddy wanted to turn his grief into good 💙

Now, with the proceeds from his Bald Eagle t-shirt and plush in hand, he soared into @MoffittNews to visit with patients and staff!

[Gabby Shirley @Gabby_Shirley_]

today, Darren Raddysh donated $20,000 to Moffitt Cancer Center … this money comes from the sale of the bald eagle T-shirts and stuffed animals

his why — his dad, Dwayne, who passed away from cancer in March

[Jeffrey West @mathoncbro]

.@fpradelli94 & I found a compelling candidate for the first published mathematical model in oncology: Hutchinson's 1886 proposal of Malthusian growth law for tumors.

The 2nd math onco? A rebuttal of the 1st, a mere ~3 months later. [some things never change]

[Jeffrey West @mathoncbro]

Optimization of sequential therapies to maximize extinction of resistant bacteria through collateral sensitivity

https://t.co/nwtEsML6AB

[Jeffrey West @mathoncbro]

"Universal principles of cell population growth follow from local contact inhibition."

We just published an integrative experimental-mathematical approach to defining growth laws in the context of cell-cell interactions:

https://t.co/ieOv7inrrs

[Jeffrey West @mathoncbro]

.@fpradelli94 & I found a compelling candidate for the first published mathematical model in oncology: Hutchinson's 1886 proposal of Malthusian growth law for tumors.

The 2nd math onco? A rebuttal of the 1st, a mere ~3 months later. [some things never change]

[Jeffrey West @mathoncbro]

"Universal principles of cell population growth follow from local contact inhibition."

We just published an integrative experimental-mathematical approach to defining growth laws in the context of cell-cell interactions:

https://t.co/ieOv7inrrs

[Jeffrey West @mathoncbro]

@MoffittNews @fpradelli94 Franco is an awesome addition to Moffitt's @mathonco department! He has experience in computational models of evolution of drug resistance and in constructing Artificial Intelligence pipelines for bibliometric science of science.