@Elijahjstacy Lechner et al: Conclusions Cardiomyopathy with systolic heart failure is the leading cause of death and lower LVEF is an independent predictor of mortality at younger ages in patients with DMD. Patients with DMD appear to be undertreated with respect to heart failure drug therapy
@Elijahjstacy FDA cites Lechner et al, PMC10505954 https://t.co/deia51EMTh:
Those who died of cardiac death (53% of known causes of death) had significantly lower LVEF at the time of death (LVEF −11.0%, p=0.035) compared with non-cardiac death and tended to die at a younger age.
@Elijahjstacy https://t.co/r7eYb4ptjJ Soslow et al, Cardiovascular Measures of All-Cause Mortality in Duchenne Muscular Dystrophy, published August 2023
@Elijahjstacy Don't forget to mention the Soslow study that received NIH funding and served as external comparator. The study had 15 deaths (19%) after 4.9 years at an median age of 17 years. Zero deaths in HOPE2 OLE and the patients are around 21.5 years old now. Also no death in Hope3
@marcfriedrich Bei 10k Gold wird das GSR zwischen 40:1 und 20:1 liegen, Silber also mindestens bei 250$. Ich denke, 100 Silber und 5k Gold werden wir 2026 sehen.
@FriedrichReport Der Chart ist eindeutig SSV.V, die ich natürlich auch habe (und warrants von den PPs). Es gibt aber einige mit deutlich höheren Silbergraden, z.B. KUYA.V oder OCG.V
#NewsRelease | Kuya Silver to Accelerate Bethania Silver Mine Throughput with Modernization Program and Geological Work to Unlock Resource Growth Potential
Visit our website for the full release: https://t.co/ZPvtS9rz3j
#Silver#SilverStocks#JuniorMining#SilverMining
@Playteaux1@RealRickRule Rick, I am surprised that you share this. While I certainly agree in principal, there is a major flaw in the assumption : You don't pay 500k cash into it when you start working and then accrue 7% on the 500k for 30 years.