mayankjoshi

[Swarajya @SwarajyaMag]

Researchers At IIT Delhi Found That Covid-19 Could Be Lab Made, Were Forced To Withdraw Paper

https://t.co/YVZ1vdZQVe

[mayankjoshi @mayankjoshidj]

@DrSharmarke @CEFMC2020 @bragadario Thanks for sharing the research paper @DrSharmarke this is nice work and I learned something new. Now I am eagerly waiting for the lecture of prof. @bragadario to know more about this.

[mayankjoshi @mayankjoshidj]

@DrSharmarke @CEFMC2020 Thanks, @DrSharmarke this has been a great point of debate on the nomenclature of the salts or cocrystals so technically both are right. These are designed by the solvent drop grinding method with a stoichiometric ratio of both drug and coformer via ΔpKa rule of three.

[mayankjoshi @mayankjoshidj]

@tejender_thakur IC50 might be enhanced (due to higher solubility affect the bacterial cell wall permeation which has been seen in MIC study) due to this higher solubility it absorbed faster in Caco-2 cell line

[mayankjoshi @mayankjoshidj]

@tejender_thakur Yes levofloxacin is class I drug but we want to form some other solid phase of the drug by cocrystallization to know its effect on biological activity and we have found IC50 four times more potent