Manuel Mayr

🇬🇧🇪🇺

[Manuel Mayr Lab @Vascular_Prot]

The Imperial Imperial vulnerable plaque 2023 meeting (https://t.co/WrSI8mGcrj) is starting today and @mayrproteomics is presenting the work on the #Proteomic Atlas of #Atherosclerosis!
#VPM2023

[Manuel Mayr Lab @Vascular_Prot]

Congratulations @SeanBurnap for the MJ Dunn fellowship award👏! #BSPR

[Manuel Mayr Lab @Vascular_Prot]

Excited to share @SeanBurnap's latest work in our lab, about the interactions between SARS-CoV-2 spike protein and high-density lipoproteins! #XLMS #HDL
https://t.co/NJ2VDwxOi9

[Manuel Mayr Lab @Vascular_Prot]

#Proteomics study challenges SERCA2a reduction as a hallmark of #heartfailure, finding no changes in cardiac explants:
https://t.co/wnCcFa5DWZ
@ragone_isabella @CircAHA #ResearchLetter @mayrproteomics @Vascular_Prot #research #cardiovascular

[Manuel Mayr Lab @Vascular_Prot]

Our latest publication doubles the coverage of atherosclerotic #plaque #proteome and reveals a sex-specific biosignature, enriched in large-aggregating #proteoglycans, for #CVD outcome prediction.
https://t.co/CSJH1Rxy0N
@CircAHA @k_theofilatos @mayrproteomics @JohannWojta

[Manuel Mayr Lab @Vascular_Prot]

Our new home: #WhiteCityCampus at @imperialcollege! Excited to be there and for the new opportunities being unravelled for high-quality #cardiovascular #research!
https://t.co/klrLKD3a3x

[Manuel Mayr Lab @Vascular_Prot]

Excited to announce that our lab has officially moved to the @imperialcollege as a member of the Sir Michael Uren Hub. Looking forward to great advancements in #cardiovascular #proteomics #research.
https://t.co/rD6mFa73ua

[Sean Burnap @SeanBurnap]

Delighted to share perhaps the last of my work to come from my time in the Mayr lab @Vascular_Prot. Here we used cross-linking mass spectrometry #XLMS to uncover interactions between the SARS-CoV-2 spike protein and high-density lipoproteins #HDL. https://t.co/JxxaPSMjqT 🧵1/7

[Manuel Mayr Lab @Vascular_Prot]

It was such a great honour and pleasure for all of us to have Sir Magdi Yacoub visiting our lab today! @DrMagdiYacoub thank you for your contribution to #medicine and #science 🙏

[Manuel Mayr @mayrproteomics]

Last Words Of Russian Journalist Before Going To Jail For 6 Years For Te... https://t.co/zq3KAddwTZ via @YouTube

[Marv 🇺🇸🇺🇦🇵🇸 @marlowc2324]

GODDAMN!

Ecuador just absolutely obliterated Russia at the UNSC. It was so bad that Lavrov walked out 🔥🤌

Thank you Ecuador, for your principled stance & your defense of international law by calling out Russia for what it is. You are showing true leadership 👏🏼

#SlavaUkraini

[Eileen Gentleman Lab @GentlemanLab]

Please RT 🙏 Looking for a funded PhD studentship? Fab project funded by @NC3Rs using 3D #biomaterials and #proteomics to study vascular diseases. Working with the fantastic @Vascular_Prot Lab in central London🌆. Apply by 9 April!
https://t.co/YLZgX0sW97

[Manuel Mayr @mayrproteomics]

@JoePlatelet @ArcSuellen @HaoYin20 @Vascular_Prot @atvbahajournals As you previously commented correctly, it is important to provide more quantitative TMT data of platelets from human patients!

[ATVB: An AHA Journal @atvbahajournals]

Thank you everyone for joining us Today & We see you next time!! ✌️

@atvbahajournals
@ATVBCouncil
@ATVBEarlyCareer
@atvbwlc

[Manuel Mayr @mayrproteomics]

@cardiacjoshi @MaAlfaidi @ArcSuellen @Vascular_Prot @BartsHospital Great job - this PhD project was anything but easy... but you did it!

[Manuel Mayr @mayrproteomics]

@atvbahajournals @Vascular_Prot @cardiacjoshi MicroRNAs Within the Continuum of Postgenomics Biomarker Discovery https://t.co/s19SwInrEN

[Manuel Mayr @mayrproteomics]

@atvbahajournals @Vascular_Prot @cardiacjoshi We are looking at ways to better assess in vivo platelet reactivity, i.e. with circulating microRNAs that integrate platelet activation over time. Stay tuned!

[Manuel Mayr @mayrproteomics]

@atvbahajournals @Vascular_Prot @cardiacjoshi Elevated S100A8/A9 levels reflect neutrophil activation. Platelets get pre-activated by neutrophil activation, leading to a "platelet exhaustion phenomenon" during ex vivo testing. This would explain challenges with using aggregometry to guide antiplatelet therapy in acute MI.

[Manuel Mayr @mayrproteomics]

@atvbahajournals @Vascular_Prot @KingsCollegeLon @TheBHF This study in Blood from colleagues in Birmingham identifies S100A8/A9-GPIbα axis as a novel targetable pathway that induces procoagulant platelets and fibrin formation, particularly in diseases associated with high levels of S100A8/A9.

[Manuel Mayr @mayrproteomics]

@atvbahajournals @Vascular_Prot @KingsCollegeLon @TheBHF Discovery science is full of surprises - new findings often raise more questions than answers! 🤔 But this is a nice study that may partially answer this point: S100A8/A9 drives the formation of procoagulant platelets through GPIbα https://t.co/j4vXA7q9zV