@glavaidguy @rebsmoe As I like to say, the hard questions occur at the boundaries where lines are drawn that often cleave shades of gray rather than black from white
46 years ago I marched against racism in Boston. It wasn’t enough, it will never be enough until everyone not only hears but acts on the fact every day, every single day that black lives matter
From a well respected friend and intensivist/A&E consultant who is currently in northern Italy:
1/ ‘I feel the pressure to give you a quick personal update about what is happening in Italy, and also give some quick direct advice about what you should do.
@bryant_yang @glavaidguy @glen_huang I’d continue oxacillin, make sure dosing was appropriate, consider continuous infusion, ensure that this isn’t an instaiwith occult mecA and most importantly be sure that there are no focu amenable to better source control, e.g. , visceral abscesses
@BradSpellberg@ABsteward @CGentPharm @koutterson But then again, facilities that prefer to use colistin rather than a carbapenem- betalactamase inhibitor combination to treat KPC infections are not acting in their patients’ best interests. Sometimes newer (and more expensive) is really better.
@ABsteward Kind of depends on whether all CP-CRE are created equal. That not being the case, to paraphrase John Rex, multiple differing fire extinguishers are needed. Granted there is a point of diminishing returns and new classes of agents with activity vs CP-CRE are needed.
@kelechevarria And it particularly sucks when adults get measles. Adults with measles are much more likely to develop severe hepatitis and respiratory failure.