McFadden Lab

We use genetic and chemical screening approaches to study thyroid cancer, Ewing sarcoma and neuroendocrine tumors.

[McFadden Lab @McFaddenLab]

Our latest preprint is online. Thanks to many in the lab for contributing to building these cell lines over the years including James’ and Alberto’s key contributions. https://t.co/uBD0OIQT2E

[McFadden Lab @McFaddenLab]

Beautiful full moon rising over Pegasus Park last night! The group celebrated our physical move to @UTSW_RadOnc lab space in the new Section of Molecular Medicine headed by Deepak Nijhawan. @CommunityBeerCo @BioLabsNTX

[McFadden Lab @McFaddenLab]

Link to 2019 paper describing the forward genetics approach from @PovedanoJuanma in @CellChemBiol: https://t.co/qkh4MHh4IH.

[McFadden Lab @McFaddenLab]

Former student @afrank0410's latest work out today in ACS Chemical Biology. https://t.co/MtcFfJHaBb. He used a method we reported in 2019 to engineer hypermutation into cancer cell lines to find compound-resistant alleles to an LDH inhibitor. Great work Anderson!

[McFadden Lab @McFaddenLab]

Great fun with the lab at Top Golf this afternoon celebrating Haden’s time in the lab. He is off to graduate studies in physics!

[McFadden Lab @McFaddenLab]

I also want to specifically thank @DamonRunyon for funding us when this project was in its infancy.

[Cancer Discovery @CD_AACR]

Mitochondrial-encoded Complex I Impairment Induces a Targetable Dependency on Aerobic Fermentation in Hürthle Cell Carcinoma of the Thyroid, by Anderson Frank, @McFaddenLab et al.
https://t.co/FY2eBgihcU
@UTSWNews

[McFadden Lab @McFaddenLab]

Very proud of Anderson and his manuscript. I look forward to more great science from him as a postdoc with @SueBiggins at @fredhutch. Great work Anderson! This manuscript a product of Anderson's hard work and persistence and the scientific environment here @UTSWNews

[Elizabeth McKenna @ElizSMcKenna]

It's #metabolism day at @CD_AACR! Now online: Mitochondrial-encoded Complex I Impairment Induces a Targetable Dependency on Aerobic Fermentation in #HürthleCellCarcinoma of the Thyroid by Anderson Frank, @McFaddenLab, and colleagues @UTSWNews https://t.co/9VXSh7wyrZ

[McFadden Lab @McFaddenLab]

Research Scientist application link: https://t.co/ZzS3JgsRHG

[McFadden Lab @McFaddenLab]

Research Technician application link: https://t.co/APp4UlPAt1

[McFadden Lab @McFaddenLab]

New positions for 2023 open in the McFadden Lab for a research technician to work for 1-2 years prior to graduate/medical school and a research scientist with an interest in small molecule screening, CRISPR genetic screens, biochemistry, metabolism. Links to follow.

[McFadden Lab @McFaddenLab]

James from the lab delivered an awesome talk today at the NCI FusOnc2 Annual meeting! Great job!

[McFadden Lab @McFaddenLab]

Latest work from the lab out on BioRxiv from stellar student Anderson…we missed you at the CSHL meeting! https://t.co/mHwgm2sPrq

[McFadden Lab @McFaddenLab]

Back from CSHL mechanisms and models meeting. Great fun with Vicky, @PovedanoJuanma, and James from the lab, and seeing many friends and colleagues!

[McFadden Lab @McFaddenLab]

Our latest manuscript is online @CellChemBiol. Congrats to @PovedanoJuanma and the rest of the lab team on this work identifying the mechanism of cytotoxicity for TK216 that was in clinical trials for Ewing sarcoma. https://t.co/QpYDuETsFj

[McFadden Lab @McFaddenLab]

We have finally caved to the pressure and the McFadden Lab has joined Twitter! More to come...