Samarth Rangavittal

[Samarth Rangavittal @md5sam]

Pre-print on the evolution of great ape Y chromosomes, by @biomonika, @rahul_vegesna, and other colleagues & friends from the @MakovaLab & @pashadag group. Great work, all! 🦍🦧

[bioRxiv Evobio @biorxiv_evobio]

Dynamic evolution of great ape Y chromosomes https://t.co/uagvRZQQBH #biorxiv_evobio

[Samarth Rangavittal @md5sam]

@lal_avantika Not sure if sci-fi strictly excludes fantasy, but Children of Blood and Bone by Tomi Adeyemi is very good.

[John Perry @jrbperry]

Really excited to see our work on mosaic Y chromosome loss out today in @nature. Many thanks to all involved, and especially to all the @uk_biobank and @23andMe research participants who made this possible.

https://t.co/EiqVZgTxeO

[Samarth Rangavittal @md5sam]

@pashadag I remember you saying exactly this in ~2013, during a BG program meet-the-faculty session Shashi had organized :) It has stuck with me ever since!

[Sarah Zhang @sarahzhang]

I wrote about the rare, genetic anomaly that gives you more DNA from one parent than the other

https://t.co/BeKm1pHgmz

[Samarth Rangavittal @md5sam]

@slamancona @brownpundits Really enjoyed the podcast, great job guys! :)

[Samarth Rangavittal @md5sam]

Many thanks to the Genome In A Bottle consortium for making their data from different sequencing platforms (including Illumina, PacBio, 10X) available, and for enabling us to take on a project like this! Sorry about the numbering on these tweets - this is the last one (10/10)

[Samarth Rangavittal @md5sam]

My final paper from grad school on identifying Y-chromosomal contigs from whole genome assemblies was published online last week- take a look if you're interested in sex chromosomes, genome assembly, or k-mer based methods.
https://t.co/30IhfHvcoa

Here's a quick summary (1/10):

[Samarth Rangavittal @md5sam]

Our approach was to combine the strengths of both these kinds of methods - by using both proportion sharing with female and coverage from male reads to isolate Y-contigs. By doing so, we were able to show that our method performs well across different sequencing platforms. (5/10)

[Kateryna @MakovaLab]

I was very happy to put a #PhD hood today on Samarth Rangavittal (@md5sam) graduating from @BioinformPSU. Congratulations, Sam!!!

[Samarth Rangavittal @md5sam]

@pastramimachine I just received my copy of the Guide today and saw in the preface the acknowledgment of an “Andy Kern”. No relation, I’m assuming :)

[Samarth Rangavittal @md5sam]

Always wanted my photo in the New York Times 🥳

*𝘳𝘦𝘢𝘥𝘴 𝘩𝘦𝘢𝘥𝘭𝘪𝘯𝘦* Aw, dammit 🤦‍♂️

[Samarth Rangavittal @md5sam]

@awanti_sp @shramdas @saund_katie @joannamtn Indeed! :)

[Samarth Rangavittal @md5sam]

@pierre_marijon Why not the classic "putting together pieces of a jigsaw puzzle" analogy ?

[Samarth Rangavittal @md5sam]

@SandeepEmbar @neuroimm @23andMe I'm glad you asked! Here's a link to a program we started last year giving out tests for free to underrepresented groups as you say. Note that the list has changed over time https://t.co/S2ryZqbsgu

[Samarth Rangavittal @md5sam]

@neuroimm @SandeepEmbar @23andMe A totally valid point of view - but as @SandeepEmbar suggested, our disease risk predictions for South Asians can only be improved if we get more data on South Asians so its kind of a chicken-and-egg problem.

[Samarth Rangavittal @md5sam]

@A_A_Zaidi @23andMeResearch @23andMe That's right - this beta test is only for those on the V5 chip (GSA array). The full update will be available to all, regardless of chip (date TBD).

[Samarth Rangavittal @md5sam]

Our 23andMe South Asian Ancestry Composition beta is here! If you’ve got your test done in 2017 or later, please log in at https://t.co/dlZIqfcGf8… and give us your feedback so we can improve ! Here are my results 👇 @23andMeResearch @23andMe