To be a buzzkill, a reminder, in the Caribbean the indigenous population (Taino) of 400,000 estimated reduced to 60,000 in just 16 years.
Ten years before the first disease out break in the new world, meaning they all were killed due to enslavement and artificial famine.
That’s why the Caribbean began importing Africans.
It was so bad both the Spanish Crown and Catholic Church were horrified enough to enforce strict legal changes as early as 1542.