👍 My take on the current management of #lupus#nephritis (mix of the latest @eular_org & @goKDIGO recommendations). Please RT & comment🙏. I would definitely appreciate some feedback 🔄 from #nephrology colleagues as it was a tough job to assemble this slide!! 🏥
#SLE#renal
The HISTORY of #lupus 🤓
Check my new video about how, why and when the term "lupus" 🐺 appeared and discover its complex history, overlapping with that of tuberculosis and syphilis until the concepts of cutaneous lupus #CLE and #SLE were well defined.
➡️https://t.co/eMfhGEcm9L
Raoult PRE-print: 79 pts w/COVID improve, also receive HCQ
1. Not peer rvwd
2. No control group
3. Incl pts from prior study
4. Migratory/weak endpts
5. Healthy group: 41% only URI & 5% asymptomatic!?!
Not confirmatory; not progress. Need. RCTs.
PDF: https://t.co/Mbrq7bFHk0
With #coronavirus most meetings are canceled but we can still share knowledge using #twitter 👍.
🆕 Here is my lecture 🗣️
on #interferons & #lupus#SLE planned for #BBI2020. Link to pdf (46Mo): https://t.co/EcFq6c5Rln
Please leave me a comment 📖 (or RT) if you download it! 🤳
Among patients with severe antineutrophil cytoplasmic antibody–associated vasculitis, plasma exchange did not reduce the incidence of death or end-stage kidney disease.
PEXIVAS fact-RCT, PLEX v PLBO & ⬆️ or ⬇️ steroid (60% less) taper in AAV w/renal or pulm dx, @NEJM
Re:death/ESRD: no benefit to PLEX (28% vs 31%, NS and NNT ~38)
Reduced taper noninferior to standard (HR ~ 1) & fewer infxns! (27% vs 33%, NNT ~17)
Less PLEX; less steroid
Image Challenge: A 53-year-old man presented to the ED with a 1-month history of relapsing fevers, dyspnea, and rapidly progressive skin lesions. What is the most likely diagnosis? https://t.co/kQrNuVExlQ
[Nouvelle classification des #déficits#immunitaires#héréditaires] 📣
Retrouvez la nouvelle classification des #DIH (n= 416) mise à jour par le Comité d'experts de l'Union internationale des sociétés d'immunologie 👨🏫
▶️ https://t.co/wgjX2fjLUB
Systemic Inflammation and Myelofibrosis in a Patient with Takenouchi-Kosaki Syndrome due to CDC42 Tyr64Cys Mutation (outside the C-terminal domain). Tribute to a unique patient. Thank you @stutangye lab. Thanks to all! https://t.co/4hMjkL6l6U
SAVE THE DATE
La 3ème édition de la #WINTERSCHOOL des maladies #autoimmunes et inflammatoires du #RESO STRASBOURG se déroulera les 26 et 27 novembre 2020!
NEJM Case Challenge: A 44-year-old man was evaluated because of diarrhea and progressive weight loss, plus an episode of culture-negative meningitis. What is the most likely diagnosis? #casechallenge#NEJMCases https://t.co/KcKSgMovIA