Michael Holl

Ich bin ein deutscher Arzt, der begonnen hat sich für Business zu interessieren, seit die Politik Medizin betreibt

[Michael Holl @MichaelHoll20]

@BittelJulien I wish you all the best for you and your family. You are doing such a great job at educating people like me in plain English. Thank you very much and may all your wishes for your next chapter come true.

[Michael Holl @MichaelHoll20]

@RealVision 130.000€

[Real Vision @RealVision]

Good luck, everyone!

Join the waitlist below to qualify

Like + RT to spread the word... 👇 https://t.co/IfPjcyfUI2

[Michael Holl @MichaelHoll20]

@EpochTimesDE Na aber mal ganz ehrlich, ihr müsst mal sein Buch zum Klimawandel lesen. Dem Fähnchen im Wind ist alles recht, solange sein Einfluss steigt

[The Extreme Music Enthusiast @TheExtremeMusi1]

Henry Mancini performs the iconic "Pink Panther Theme" in 1983 with Plas Johnson, the original saxophonist, and the Terry Gibbs Band.

[Paul Guerra @paulguerratv]

🇬🇧 It started with the fall of the British Empire.

The largest empire in history couldn’t escape one thing: debt.

As it stretched to control the world, its foundation weakened.

Then came a rising power in Europe: Germany.

[Michael Holl @MichaelHoll20]

@cb_doge @elonmusk Not true, I am pretty sure there will be an Anesthesist 😉

[Alex Gurevich @agurevich23]

Every cycle end the Fed policy progresses in the same fashion:
1. We are overheating: hike!
2. Stocks aren’t the economy, stay the course.
3. Stocks Are the economy. We’re watching the market closely.
4. Numbers are mixed: pause and resume.
5. Just one cut.
6. Low for longer.

[Brandon Luu, MD @BrandonLuuMD]

Incredible. Even in the aftermath of an earthquake, these surgeons operated outdoors.

When everything else crumbles, doctors still find a way to care for their patients.

[Inferam @InferamAI]

Exercise through games for kids

[Kevin Carpenter @kejca]

Warren Buffett: "Go to work for whomever you admire the most. You can't get a bad result. You'll jump out of bed in the morning."

[Dr. Rhonda Patrick @foundmyfitness]

Glutamine is one of my top supplements to take for reducing susceptibility to illness during cold and flu season.

Immune cells prefer glutamine as a fuel source. During infections, they consume this amino acid at a rate similar to or greater than glucose.

It might be especially important for endurance athletes–randomized controlled trials have shown that glutamine supplementation reduces upper respiratory tract infections after a marathon by up to 32%.

I've noticed that I'm sick less often and when I am sick, my symptoms are much less severe since starting a regimen of ~5 grams of glutamine, which I take on training days (most days of the week).

[Dave G @daveginvesting]

$RKLB CEO Peter Beck spoke at the 37th Annual Roth Conference on March 17th. These are my notes:

Mynaric Acquisition:
- Optical comms have been a nightmare in the industry. Hard tech, few people do it. Mynaric had challenges in production scaling and that's where we're really good. We did the same with Sinclair - 150 wheels per year to thousands.
- We have good systems and teams for sorting stuff like this out. We think the tech is very good, it's just the production issues.

Flatellite:
- Every contract we take is strategic in teaching us and building our capabilities. Flatellite is the next evolution.
- Flat Pack satellites are closely coupled with the rocket. Neutron and Flatellite very much tuned to each other.
- I think it will be very difficult from cost standpoint to be competitive with Starlink when you don't have launch (👀)
- I wouldn't say we are necessarily building our own Starlink
- Do you see direct to mobile as a big market that you might get into? "I'm not exactly sure, to be honest with you" It looks big and interesting. Demand is there, jury out on how big market will be.
- We'll never put the company in the position where we are betting it on a single particular application

Neutron:
- Vulcan 1st Launch Slipped a Decade, so Neutron's slip of a matter of months is actually pretty good in context
- Why are you able to execute when others struggle with new Rockets? - Capital is not necessarily an indicator of success (VO was well capitalized). Yes the numbers are scaled up with Neutron (10 inch valve vs 2 inch valve), but a lot of it feels exactly the same except with the added experience.
- Anybody who says they will go from 1 launch to 10 launches is disingenuous.
- I think the window for new medium class launchers is about to close, once Neutron is on the pad, why will a customer want to take a risk on new rockets? Only SpaceX and Rocket Lab have shown they can scale and be reliable. Don't think there will be many competitors in Medium launch. Furthermore, when you build the spacecraft too it becomes even harder to compete against that as a pure launcher. Pure Launch is a tough place to be.

Software:
- We can use and iterate in-house until we think it is great, then flip it to market

[CardiovascularCorner @TrackYourHeart]

Understanding the Mechanisms of Supraventricular Tachycardia (SVT):

1️⃣ Atrial Flutter (Aflutter):
A macro-reentrant circuit around the tricuspid valve in the right atrium. The electrical activity travels in a circular pattern, often leading to a characteristic "sawtooth" pattern on the ECG.

2️⃣ Atrioventricular Nodal Reentry Tachycardia (AVNRT):
A reentrant circuit within the AV node and the surrounding perinodal tissue. The impulse travels in a loop between the fast and slow pathways within the AV node, leading to a regular, narrow QRS tachycardia.

3️⃣ Orthodromic Atrioventricular Reentry Tachycardia (AVRT - Orthodromic):
The impulse travels down the AV node and up an accessory pathway (like the bundle of Kent), resulting in a narrow QRS complex due to normal conduction through the ventricles.

4️⃣ Antidromic Atrioventricular Reentry Tachycardia (AVRT - Antidromic):
The impulse travels down the accessory pathway and back up through the AV node, leading to a wide QRS complex as the ventricles are activated abnormally.

5️⃣ Atrial Tachycardia (AT):
An ectopic focus in the atrium generates rapid, organized electrical activity, overriding the sinus node as the dominant pacemaker.

6️⃣ Atrial Fibrillation (AFib):
Multiple wavelets of electrical activity circulate chaotically within the atria, causing an irregular ventricular response through variable conduction via the AV node.

7️⃣ Multifocal Atrial Tachycardia (MAT):
At least three distinct ectopic atrial foci fire independently, leading to irregular P waves with varying morphology and an irregular ventricular response.

Ref: Link MS. NEJM

#Cardiology #SVT #Arrhythmia #Electrophysiology

[Balaji @balajis]

What comes next?
Well, we're building startup societies.
Come join us at https://t.co/2nrpUHOXtU.

[IMCrit @IM_Crit_]

ICU ID - Pneumonia:

Since we are still facing a tsunami of respiratory tract infections, it's a good idea to review the 2023 clinical
practice recommendations for diagnosis, empirical treatment, & antibiotic therapy for severe community-acquired pneumonia (sCAP)

[NephroPOCUS @NephroP]

Finally found a great #POCUS #anatomy correlation figure to go with this quiz!
#FOAMed #echofirst

[NephroPOCUS @NephroP]

#POCUS quiz of the day:
What is the linear structure arrow is pointing to?
How is the LV systolic function?
#MedEd #FOAMed #Nephpearls

[Dr. Rhonda Patrick @foundmyfitness]

A single night of poor sleep can slash your insulin sensitivity by up to 25%.

This means even one bad night can significantly impact your body's ability to manage blood sugar levels.

But it's not just about how many hours you sleep—a new study highlights that bedtime matters, too.

Participants who slept between 4 and 7 hours each night had larger spikes and more variability in blood sugar (as measured by continuous glucose monitors or CGM) compared to those getting at least 8 hours.

Going to bed after midnight was also linked to poorer glucose control.

The worst-case scenario is less than 5 hours of sleep and a late bedtime. Interestingly, late sleepers who still got 8+ hours were somewhat protected, while going to bed early didn’t offset the effects of too little sleep—metabolic benefits only came with sufficient sleep duration.

The takeaway? You can't offset inadequate sleep simply by turning in early. But if you're forced into a late bedtime, prioritizing a full 8 hours of sleep can lessen the negative impacts on blood sugar regulation.

Another strategy if sleep isn't ideal? Exercise. Studies show that performing HIIT minimizes the effects of sleep loss on insulin sensitivity and other measures of metabolic control.

Study PMID: 40042843

[Nicholas Fabiano, MD @NTFabiano]

Reducing sugar intake in the first 1000 days of life is associated with a reduced risk of chronic diseases in adulthood.

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