Michael George

CTO @NanionTech:
Automated #patchclamp,
#ionchannels #ionchannel #membranetransporters research #cardiacsafety #cardiomyocytes #electrophysiology

[Michael George @michaelnanion]

Was Politikern schwerfällt zu sagen, weil jede Kritik zu brutalen Strafen von Trumps Seite führt, können wir vielleicht am besten auf der Straße ausdrücken - und sollten dies auch tun.

Das ist einfach unerträglich und widerlich!

2.

[Michael George @michaelnanion]

Selenski im Weissen Haus:

Wenn das jetzt nicht die Zeit ist aufzustehen gegen die Amerikanische Politik, wann dann?

Schon Musk und Vance' Einflussnahme vor der Wahl hätte uns vor die Amerikanischen Botschaften treiben müssen.

1

[Chris Mathes @MathesChris]

Please retweet!

[Michael George @michaelnanion]

Interesting narrowing in Michigan...

[Nanion Technologies @NanionTech]

𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐍𝐨𝐭𝐞: Electrophysiological recordings of LGIC and AA transporters in iCell® GlutaNeurons

Download here: https://t.co/BERkziP4AH

#GABA #hiPSCs #electrophysiology #ionchannels #glutamate

[Nanion Technologies @NanionTech]

𝗣𝘂𝗯𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗔𝗹𝗲𝗿𝘁: A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models

Download the Publication: https://t.co/iUP8OJF2t3

#CiPA #proarrhythmia #Electrophysiology #riskprediction

[Nanion Technologies @NanionTech]

Screening compounds for activity on the hERG channel using patch clamp is a crucial part of safety testing.

Don't miss this benchmarking guideline of safety testing
Find out more: https://t.co/EBfb4EeGgh

#automatedpatchclamp #hERG #ionchannels #CiPA #highthroughputscreening

[Nanion Technologies @NanionTech]

Pharmacology of NaChBac with human NaV1.7 channels reveals that while some drug interaction mechanisms are conserved, others exhibit striking divergence.

Learn More: https://t.co/KqlF9fvAmT

#Sodiumchannels #ionchannels #drugdiscovery #electrophysiology #automatedpatchclamp

[Nanion Technologies @NanionTech]

𝗣𝘂𝗯𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗔𝗹𝗲𝗿𝘁: Then & Now - Automated Patch Clamp in Drug Discovery.

We summarize the main changes in the last decade and attempt to look into the future of what’s to come.

Download the Free Publication: https://t.co/5hZgm71Kkv

#patchclamp #ionchannels

[Nanion Technologies @NanionTech]

𝗣𝘂𝗯𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗔𝗹𝗲𝗿𝘁: Integration of mechanical conditioning into a high throughput contractility assay for cardiac safety assessment

Download the Publication: https://t.co/oDr77LQ4s0

#CiPA #Cardiotoxicity #Proarrhythmic #invitro #cardiaccontractility

[Michael George @michaelnanion]

Productive brother of @DasmachineNU in @VanderbiltU: High throughput characterization of #SCN5A #ionchannel variants https://t.co/8YpP2LlE2J https://t.co/v7VxjitXOr #ionchannels

[AJHG @AJHGNews]

New! Glazer et al. use high-throughput patch-clamp assays to reclassify SCN5A VUS https://t.co/plbaRafwBB

[Michael George @michaelnanion]

#ionchannels are good against everything - even #Pandemics. Interesting target for machines like @DasmachineNU!

[Nanion Technologies @NanionTech]

Publication Alert: Endo-lysosomal two-pore cation channels have emerged as a potential novel targets for SARS-CoV treatment.
@sciencedirect (𝐂𝐞𝐥𝐥 𝐂𝐚𝐥𝐜𝐢𝐮𝐦 - 𝐕𝐨𝐥.𝟖𝟖; 𝐉𝐮𝐧𝐞 𝟐𝟎𝟐𝟎)

Learn More: https://t.co/94ThuXNg3A

#Covid-19 #SARS-CoV2 #Lysosome #IonChannels

[Michael George @michaelnanion]

Great for me who has always been a wonderer. Now I can stop (converted into a reader)
Thanks for the great work @DasmachineNU! #ionchannels #stemcells #cardiomyocytes

[DasMachine-NU @DasmachineNU]

Ever wonder how to perform full concentration-response curves for 5 drugs using human iPSC-cardiomyocytes and determine Kon/Koff values? You can stop wondering and start reading: https://t.co/gxI2V0mhTQ #ionchannels #arrhythmia #sodiumchannel

[Michael George @michaelnanion]

Better meet online than not at all. #channelopathies2021 already in June 2020 (25th and 4th!)
📆see also: https://t.co/qKM40xXdTP
Prof. Al George (Northwestern University) and Jen Q. Pan (Broad Institute of MIT and Harvard) on decrypting ion channels:

[Hugues Abriel @[email protected] @SwissIonChannel]

The #channelopathy2021 steering committee is looking forward to seeing you online on June 25, 2020, for these two exceptional webinars! RT to reach all our ion channel aficionados! BTW: we would have been meeting in Québec on that date if...

[Michael George @michaelnanion]

Good news for #ionchannels.
Welcome back!

[Michael George @michaelnanion]

Retweet against #Alzheimers!

[Antoine TRILLER @antoine_triller]

PLEASE RETWEET: 3 years postdoc funded project on “Alzheimer: toward innovative therapeutic” Focus on membrane molecules. Cell and mol biol, single mol imaging and magnetic tweezers. Aim: interfering with A-beta and Tau assemblies binding to neurons. Mail: [email protected]

[Michael George @michaelnanion]

Warm welcome to the new #ionchannel family in the #ionchannels world!

[Michael George @michaelnanion]

Unique chance to realize your #ionchannel ideas.

[Nanion Technologies @NanionTech]

"There is no time like the present!" Don't miss this unique limited time opportunity.

Click here to learn more and apply: https://t.co/zGwgfYATE4

#Electrophysiology #IonChannels #SyncroPatch

[Nanion Technologies @NanionTech]

Do you have cardiomyocytes generated from diseased backgrounds to study? Or engineered genotypes, where you want to capture phenotypic differences in electrophysiologic or contractile behaviour?

Learn More: https://t.co/6xSHqTPkp4

#iPSC #cardiac #cardiomyopathy #hypertrophy