Mike Berkowitz

Co-Founder & Principal @ThirdPlateau. Executive Director of Democracy Funders Network. Social impact strategist. Food addict. Global circumnavigator.

[Derek Thompson @DKThomp]

This has quietly been a miracle month in medicine.

In the last 5 weeks we’ve got news on:

- retatrutide, the triple agonist GLP-1 from Lilly, basically melting fat and body-wide inflammation at record levels
- RevMed’s new pancreatic cancer drug showing unprecedented abilities to extend life
- small trial of a one-and-done PCSK9 gene editing therapy for slashing LDL cholesterol
- Mayo’s AI-assisted radiology showing vastly improved cancer detection
- this new therapy for metastatic solid tumors

This stuff is at varying levels of evidence. Retatrutide is ~100% on its way, other stuff needs more clinical trial data. But put it together and we’re maybe on the verge of majorly reducing the mortality of heart disease and cancer, the two leading causes of death in America.

[Mike Berkowitz @mikeberkowitz]

@SarahLongwell25 @mattyglesias Ditto

[Greg Lukianoff @glukianoff]

Simply horrifying.

We must have the highest tolerance for opinion and absolutely no tolerance for violence.

[Mike Berkowitz @mikeberkowitz]

Read this post from @YaelEisenstat. Egregious and unacceptable for our government to be acting this way.

[Yael Eisenstat @YaelEisenstat]

I'm one of the 37 targeted below by DNI Tulsi Gabbard. I haven't had a clearance nor worked in government since 2013. This is political theater & a dangerous government abuse of power to punish private citizens for openly exercising their 1st Amendment rights. My full statement:

[Mike Berkowitz @mikeberkowitz]

This is totally wild.

[Yashar Ali 🐘 @yashar]

The last living grandson of President John Tyler has died.

Harrison Ruffin Tyler was born in 1928 and died in 2025.

His grandfather, the 10th President of the United States, was born in 1790 and died in 1862.

[Mike Berkowitz @mikeberkowitz]

I am deeply concerned about the ways in which philanthropy and civil society more broadly will be inappropriately targeted by the incoming administration and its allies. https://t.co/lnQEqAb1NE

[Ben Wikler @benwikler]

If we’re going to take on Trump, Republican extremists, and move our country forward, the Democratic Party needs to be stronger. I'm running for Chair of the Democratic National Committee to unite the party, fight everywhere, and win. Join me. 🧵

[Mike Berkowitz @mikeberkowitz]

This is the way.

[Ezra Klein @ezraklein]

Friends don't let friends debate the future of the Democratic Party without being clear on whether they're debating the 2024 election or the 2016-2024 shifts in the electorate.

The former you can explain with inflation. The latter you can't.

[Mike Berkowitz @mikeberkowitz]

💯

[Josh Marshall @joshtpm]

Ben Wikler should be the next head of the DNC. That's a fighting choice. Someone who has demonstrated the kind of persistent and effective party building and infrastructure building that generates results. Dems didn't win Wisconsin this year. But it was the closest ...

[David French @DavidAFrench]

Nope. Nope. Nope. Trump won fair and square. Follow Harris's lead. She conceded. It's over.

[Sarah Longwell @SarahLongwell25]

Don’t do this.

[Mike Berkowitz @mikeberkowitz]

@danpallotta I hope you'll speak up if he doesn't.

[Mike Berkowitz @mikeberkowitz]

Agreed 100%.

[Mike Berkowitz @mikeberkowitz]

This is the way.

[Anne Applebaum @anneapplebaum]

No, I am not going to write about what Harris should have done, and pretend that my personal biases/preferences have some kind of universal significance

[Anne Applebaum @anneapplebaum]

No, I am not going to write about what Harris should have done, and pretend that my personal biases/preferences have some kind of universal significance

[Mike Berkowitz @mikeberkowitz]

@ilyseh Princess Leia

[Sarah Longwell @SarahLongwell25]

I am begging General Kelly to call a press conference and talk straight to the American people about all the things he saw and heard.

[Sen. Elissa Slotkin @SenatorSlotkin]

This is disgraceful. If your idea of protest is aligning yourself with a brutal terrorist group, you have lost your way. You are terrorizing Jews and you are doing great harm to the people you’re claiming to support.

[Joe Biden @JoeBiden]

And if you’re with us, donate to her campaign here:
https://t.co/A0T3v7ItQm

[Mike Berkowitz @mikeberkowitz]

@jsfreed Ha - way to make it happen @jsfreed!