Neoadjuvant nivolumab plus ipilimumab results in a substantial pathological response in most patients with mismatch repair–deficient colon cancer and appears to be safe. Read the full NICHE-2 phase 2 study results: https://t.co/KCLkvTiaFy
Key consideration: all agnostic targets approved in the past could be evaluated with NGS
The agnostic approval of T-DXd however requires HER2 IHC to be performed to identify the target.
Important to raise awareness on the need to expand HER2 testing across cancer types!
@PTarantinoMD Exactly. NGS is not going to identify most targets of new ADCs and IHC as currently performed has significant limitations. Much more still to do. I would like to discuss this topic more with you Paolo.
@nlinmd@drsarahsam Great data. I would love to discuss more with each of you. Former colleagues and I are working on a new CSF assay to address such cases. [email protected]
@HerrPath@Pathologists Join us at CAP HOD in a few weeks for roundtable discussions on pathologist #careers in different practice settings, including #biotech.
😎🙌🏻 if you are a pathology advocate that works with students become a @Pathologists Pipeline Champion! Share ideas and successes to ensure the future of the profession we love. Love this group #PathTwitter
Finding #HER2 amplification in #breastcancer tumor cells in the CSF is critical because anti-HER2 targeted therapy provides one of the best options for physicians treating patients who have developed the life-threatening complications of LMD. https://t.co/3MYJpSLsTK
Biocept and Aegea announce co-development of quantitative RT-PCR based test for SARS-COV-2/COVID-19 which discriminates strain types. #COVID19#strains#testing#SARSCoV2#CLIA
https://t.co/LHsFqxRcD7
Biocept and Protean establish collaboration to demonstrate the potential of Biocept's Target Selector EGFR assay in tissue and fluids. #liquidbiopsy#EGFR#NSCLC https://t.co/GOItWFdgpP
A UArizona Health Sciences-led study of prehospital care guidelines for EMS personnel treating traumatic brain injury (TBI) among children found deaths from severe #TBI can be nearly eliminated if the guidelines are implemented by first responders. https://t.co/X9DHVuyvFj