Rust Lab

circadian rhythms, microbiology, systems biology

[Rust Lab @mikerustlab]

@CellRaiser_ @CellCellPress @born2raisecell wow amazingly cool!

[Rust Lab @mikerustlab]

Now out: our collaboration with Qi Ouyang and Yuhai Tu. Direct cryo-EM observation of coupling between subunits in clock protein KaiC. Each protein complex acts a cooperative switch and the daily phosphorylation cycle changes the free energy of the states.
https://t.co/BKP76szbhY

[Rust Lab @mikerustlab]

Thrilled to be involved with two new Chicago centers in focused on biophysics and mathematical approaches to biology!
Postdoctoral opportunities:
https://t.co/QJJGJDv3S4
https://t.co/QrOH9zWDr7
Please reach out esp. if interested in oscillators at microbe or tissue level

[Rust Lab @mikerustlab]

Join us at UChicago to do a postdoc at the interface of biological and physical sciences. Applications for the 2022 Yen Fellowship competition due November 1. https://t.co/C5BK7ldbKI
Contact me in particular if you are interested in rhythmicity in microbes or organ systems

[Rust Lab @mikerustlab]

@jsandersonlab you cracked the code

[Rust Lab @mikerustlab]

Our new paper: discovery of a new bacterial circadian clock component which we named KidA. Interacts via PAS domains with the core oscillator to favor active fold of KaiB, fine-tuning clock period. https://t.co/gZ52kXxQj0

[Rust Lab @mikerustlab]

Apply for a tenure-track position in the dept. of Molecular Genetics and Cell Biology at the University of Chicago. We are broadly interested in mechanistic questions in biology--great group of supportive colleagues! https://t.co/LggsHgyzWk

[Rust Lab @mikerustlab]

@ContraPoints in retrospect, happy there is not a drop of dye in the glass in this photo

[Rust Lab @mikerustlab]

@theosysbio Rinzel and Ermentrout's easy treatment of a driven Kuramoto oscillator to understand weak forcing of a limit cycle (you can find it in Strogatz)

[Rust Lab @mikerustlab]

Now on bioRxiv, insights into architecture of biological oscillator from awesome PhD student Chaitra. We compare biosynthetic cost needed to suppress phase drift across TTFL circuits. Key determinant is which reaction steps are under regulation. https://t.co/jG3XfiF4SJ

[Rust Lab @mikerustlab]

Hot off the presses (if slightly belated) t-shirts designed by the amazing Diane

[Rust Lab @mikerustlab]

Now on bioRxiv: direct observation of cooperativity in a circadian clock protein (KaiC) by cryo-EM:
https://t.co/bubs9z2yi7

[Rust Lab @mikerustlab]

@mbeisen Our supposedly rational and individual opinions are in fact highly dependent on approval from our social groups and thus switch in a highly cooperative way?

[Rust Lab @mikerustlab]

I cannot figure out how to properly link myNCBI to eRA commons and also cannot figure out how to talk to a human who can help me. Does this just mean i am old?

[Rust Lab @mikerustlab]

@joshtpm @JamesGleick considered harmful

[Rust Lab @mikerustlab]

Microsoft Word track changes is the worst way to work on a collaborative manuscript, except for all the others

[Rust Lab @mikerustlab]

@jennifermhurley awesome!!

[Rust Lab @mikerustlab]

now i am getting angry phone calls from collectors for an auto body shop called The Rust Lab

[Rust Lab @mikerustlab]

@joshtpm obvious anagram for “Hold a Molester”

[Rust Lab @mikerustlab]

@IbrahimCisse_ awesome! very well deserved!