Lili Milani

Head of Estonian Biobank & Professor in Pharmacogenetics, Estonian Genome Centre, University of Tartu.

[Lili Milani @MilaniLili]

✨ A new star allele was born! Excited to share our first in vivo pharmacokinetic recall study involving 114 participants from @ESTbiobank with previously uncharacterised variants in CYP2C19 and CYP2D6:
https://t.co/tmIhdnuuFA #Pharmacogenomics #PharmVar #ClinPGx

[Kaja Kallas @kajakallas]

Repression cannot go unanswered.

EU Foreign Ministers just took the decisive step of designating Iran’s Revolutionary Guard as a terrorist organisation.

Any regime that kills thousands of its own people is working toward its own demise.

[Eric Topol @EricTopol]

The largest randomized trial of medical A.I.
—Over 100,000 women in Sweden
—radiologist + AI vs 2 radiologists, in follow-up
—AI added led to 29% more cancer detected, 44% reduced workload, and
—Less cancer dx in subsequent 2 years, and, when found, less aggressive
https://t.co/e1hY3F0cGo

[Hanna Maria Kariis @HannaKariis]

🎓End of an Era! I successfully defended my PhD in Gene Technology at @unitartu. 🎇

[Lili Milani @MilaniLili]

Mõnikord peetakse geenivaramut ekslikult tervishoiuasutuseks. Millist rolli täidab geenivaramu tegelikult Eesti tervishoiu innovatsioonis? https://t.co/EdSOVZAXPq

[Robin Hofmeister @Rbn_Hfmstr]

🚨 New preprint out!
We reconstructed parental haplotypes in >440k individuals (UK & Estonian biobanks) to estimate assortative mating directly in the parental generation.
This reveals intensified assortment in recent generations.
🔗https://t.co/wnag6TiWWo

[Lili Milani @MilaniLili]

Huge congrats @lehto_kelli on this achievement!! Her work has already enriched the @ESTbiobank and will continue to do so! 💙🖤🤍

[genomicstartu @genomicstartu]

Great news! Our Associate Professor of Neuropsychiatric Genomics, Kelli Lehto, has been selected to receive the European Research Council grant!

💐Congrats on that outstanding achievement!

👉https://t.co/oVmN9UgXvn

[European Journal of Human Genetics @ejhg_journal]

A study of genetic effects on adverse events from antidepressants in the Estonian Biobank: CYP2C19 and polygenic risk scores.
@ESTbiobank @MilaniLili @HannaKariis

https://t.co/L2yawUEZPO

[Robin Hofmeister @Rbn_Hfmstr]

🚨 Our parent-of-origin study is out in @Nature ! 🧬
Maternal and paternal alleles can have distinct — even opposite — effects on human traits, revealing a hidden layer of genetic architecture that standard GWAS miss.
🔗https://t.co/OWW6vGxGYI

Highlights below!

[Hanna Maria Kariis @HannaKariis]

🎉 Excited to share that our latest paper is now published!

We investigated genetic factors linked to antidepressant side effects in 13,000 individuals from the @ESTbiobank, leveraging data from questionnaires and clinical notes using NLP.
https://t.co/Easbg4XDet

[genomicstartu @genomicstartu]

🧬Call for poster presentations is now open!
Showcase your research to a diverse audience at #GeneForum2025.
40 poster spots available — connect, share & get feedback from the field.
📅 9–10.09 2025 | Tartu, Estonia 🇪🇪
📝 Rolling deadline – apply early!
👉https://t.co/rSofiL6OnQ

[Lili Milani @MilaniLili]

Excited to share our recently published overview of the @ESTbiobank 🧬
We highlight the unique features of the biobank and the conducted scientific research, including the many recall studies that have been carried out over the years:
https://t.co/q7k7f2CuS8

[Lili Milani @MilaniLili]

THANK YOU to @Maris_tweet @silvakasela Laura Birgit Luitva, @kristi_krebs and Märt Möls for the thorough work - so many nuances in deriving accurate dosing! And thank you 🇪🇺@REALMENT_H2020 and the Estonian Research Council for the funding.

[Lili Milani @MilaniLili]

💡Can we use real world drug purchase data to study the genetics of medication dosing?

We explored this by analyzing 20 years of digital drug dispensing data linked to the @ESTbiobank which hosts 212,000 genotyped participants. 🧵

📄 https://t.co/4AfF6KxwAw

[Lili Milani @MilaniLili]

Take-home messages:
🔹Drug purchase data is reliable for deriving medication doses at scale.
🔹 Genetic associations capture biological effects and the nature of EHR data.
🔹Both #PGx and polygenic liability should be integrated to advance #precisionmedicine.

[genomicstartu @genomicstartu]

Save the Date! 📅 24th International Gene Forum takes place Sept 9–10 2025 in Tartu 🇪🇪
🧬Welcome to the premier #genetics & #genomics conference in the Baltics.
More info: https://t.co/k0pReEDwF6 Registration for #GeneForum2025 opens soon—stay tuned!

[Lili Milani @MilaniLili]

@abkhaleel @MMuizzu @unitartu Thank you for visiting the @ESTbiobank and @genomicstartu! It was an honor to host President Dr @MMuizzu & the delegation, and engage in fruitful discussions about advancing digital health and genetic research. Collaboration across nations is key to innovation in genomics. 🌍🔬