Harsa Mitra

Doctoral student @ardekani1 research group, @PurdueME.
Interested in complex fluids and flows in biological systems. Previously @UHengineering. Views are my own

[Steven Strogatz @stevenstrogatz]

Explore this gift article from The New York Times. You can read it for free without a subscription. https://t.co/u7CuBlZie0

[bioRxiv Biophysics @biorxiv_biophys]

Anomalous diffusion of nanoparticles in semidilute hyaluronic acid solutions https://t.co/kLmLFXrnzQ #biorxiv_biophys

[Harsa Mitra @MitraHarsa]

@ANSTO A tandem was performed to study additional mixing techniques and correlate them to biological performances.

Preprint: https://t.co/UYdVSB9mL3

[Harsa Mitra @MitraHarsa]

What’s the best mixing technique to form lipid nanoparticles? 🧪Hand pipetting, microfluidics, impinging jets, vortex mixers — each creates LNPs that look and behave differently.

[Harsa Mitra @MitraHarsa]

Read more on our team's investigation, part of the Eli Lilly–Purdue Research Alliance, and in collaboration with
@ANSTO
Preprint out now: https://t.co/J3lBJZpbe0

[Harsa Mitra @MitraHarsa]

Our takeaway: flow regime, not just formulation, dictates how LNPs self-assemble. Mixing conditions shape the very structure and performance of the nanoparticles. Scaling up from bench to manufacturing means rethinking how we mix, not just what we mix.

[Harsa Mitra @MitraHarsa]

@ANSTO A tandem was performed to study additional mixing techniques and correlate them to biological performances.

Preprint: https://t.co/c6aek5YRFm

[Harsa Mitra @MitraHarsa]

Read more on our team's investigation, part of the Eli Lilly–Purdue Research Alliance, and in collaboration with @ANSTO
Preprint out now: https://t.co/95duSXaAoI

[Purdue Engineering @PurdueEngineers]

Our Vibrant Community Art Exhibition featured amazing works of creativity by Purdue Engineering staff, faculty, and students, each piece telling a story of imagination, innovation and connection.

If you missed the reception, the artwork is on display at Armstrong Hall. Congratulations to our artists and thank you to the Vibrant Arts Committee!

#PurdueEngineeringIsVibrant

[All day Astronomy @forallcurious]

The point where 'space' begins!

[International Space Station @Space_Station]

The Southern Lights, also known as the aurora australis. Wait till the end.

[bioRxiv Biophysics @biorxiv_biophys]

Effects of arginine on the interfacial behavior of proteins https://t.co/KSkKOB1fIL #biorxiv_biophys

[Purdue Weldon School of Biomedical Engineering @PurdueBME]

💉 Why do injections work better in some places than others?

A new study from Purdue BME dives beneath the skin to find out. By analyzing how tissue from the breast, belly and neck responds to stress, researchers uncovered major differences in stiffness, thinning and lipid content across regions and depths.

These insights could lead to smarter, more personalized drug delivery—tailored to where, how and who it's being delivered to.

🧪 Study by Harsa Mitra, Evelyn Nonamaker, Ria Corder, Luis Solorio and Arezoo Ardekani
📖 Annals of Biomedical Engineering
🔗 Read more: https://t.co/stNgXrVA24
#PurdueBME #BiomedicalEngineering #DrugDelivery #InjectionDesign #SkinMechanics #ResearchImpact

[Harsa Mitra @MitraHarsa]

Physics-Informed Neural Network-Based Inverse Framework for Time-Fractional Differential Equations for Rheology https://t.co/7rkyVVLi3z #mdpibiology via @Biology_MDPI

[ABME @ABMEjournal]

Why do injections perform differently depending on where they're given, and how could we improve their effectiveness?

To shed light on these questions, researchers studied how the skin's viscoelastic properties – including how it stretches, deforms, and returns to shape – vary across different anatomical sites and depths.

Using shear rheology and lipid content analysis, the team examined skin from the breast, belly, and neck, revealing that responses to stress and strain vary significantly by tissue depth, sex, and location. They observed strain-stiffening and shear-thinning at high strain amplitudes, and found that lipid levels play a key role.

These findings highlight the limitations of some preclinical models and point to new ways to tailor drug delivery methods across patient populations.

𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: https://t.co/BzAZV50wbV

𝗦𝘁𝘂𝗱𝘆: Rheological and Lipid Characterization of Minipig and Human Skin Tissue: A Comparative Study Across Different Locations and Depths

𝗔𝘂𝘁𝗵𝗼𝗿𝘀: @MitraHarsa, Evelyn Nonamaker, Ria D. Corder, Luis Solorio, and Arezoo M. Ardekani

@LifeAtPurdue
@PurdueEngineers
@PurdueBME
@PurdueME

𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗺𝗮𝗻𝘂𝘀𝗰𝗿𝗶𝗽𝘁: https://t.co/Gyz8DNneUg