MJ Knepper

“From what we get, we can make a living; what we give, however, makes a life.” -Arthur Ashe 💥 #BeAuthentic 🙏❤️ 🇺🇸🚂 My opinions are my own!

[SciTech Era @SciTechera]

This is HUGE: Scientists have found a way to regenerate knee cartilage and prevent arthritis.

A new study from Stanford Medicine shows that blocking an age linked protein called 15-hydroxyprostaglandin dehydrogenase (15-PGDH) can restore cartilage that normally wears away with aging.

In mice, inhibiting 15-PGDH reprogrammed existing cartilage cells (chondrocytes) into a more youthful, regenerative state. Cartilage thickness increased, joint structure improved, and inflammation dropped, without using stem cells.

The treatment also prevented osteoarthritis after ACL-like knee injuries. Injured mice given the inhibitor for about 4 weeks avoided the rapid cartilage breakdown seen in untreated animals, which typically developed arthritis within the same timeframe.

Importantly, when human knee cartilage samples from joint replacement patients were treated in the lab, researchers observed reduced cartilage degeneration gene activity and signs of renewed cartilage formation.

An oral version of the same 15-PGDH inhibitor is already in early clinical trials for age related muscle weakness, suggesting a potential path toward human therapies for joint degeneration in the future.

[MJ Knepper @mjknepper]

Gotta get the bird!!!

[MJ Knepper @mjknepper]

@MrsErikaKirk I am so very sorry for your loss! Sending love. ❤️

[MJ Knepper @mjknepper]

I’m sitting on my back porch watching many people pull in and park in private lots to head to the theatre; people either can’t read or are extremely entitled! 🤦‍♀️

[Elon Musk @elonmusk]

The same people who demanded that you have a vaccine ID to travel are now demanding that there be no ID for voting

[Motivational Quotes @motivational]

Soon

[MJ Knepper @mjknepper]

“This simple, brief reflection asks little compared with what we have asked of our servicemen and women” 🇺🇸❤️🇺🇸❤️ https://t.co/2x0JRbjp6T

[CBS Sports College Basketball 🏀 @CBSSportsCBB]

The feed ✅
The finish ✅ @PennStateMBB

[MJ Knepper @mjknepper]

“The kind of happiness I value is deeper – grounded in connection, purpose and hope, yet has room for sadness and anxiety, too.”
https://t.co/yb49F1jRTk

[The Wall Street Journal @WSJ]

China imposed fresh sanctions on Lockheed and a Raytheon unit over arms sales to Taiwan, as tensions with the U.S. continued to escalate https://t.co/coOCesAyoC

[MJ Knepper @mjknepper]

Anyone want to check out this new studio. #roadtrip

[The Philadelphia Inquirer @PhillyInquirer]

Alo Yoga is coming to West Walnut Street — long one of Philadelphia’s premiere shopping destinations. https://t.co/y6Q6yribbl

[PADI @PADI]

When marine bites happen, proper knowledge will help with treatments. From moray eels to sharks, get the inside scoop from @DiversAlertNetwork on biting marine critters. https://t.co/BgmVfEB7EN

[PennLive.com @PennLive]

An explosive discovery: Worker uncovers Civil War shell at Gettysburg https://t.co/1s26Zuonc7

[MJ Knepper @mjknepper]

“Magness, a Desert Storm veteran, and two other Army vets participated in the Aconcagua Challenge expedition to raise money and awareness for the Johnny Mac Soldiers Fund, which provides scholarships to military children of fallen service members.” 🇺🇸🙏https://t.co/2mcZqeUkM5

[MJ Knepper @mjknepper]

“Darkness can not drive out darkness; only light can do that. Hate cannot drive out hate; only love can do that.” #IHaveADream

[MJ Knepper @mjknepper]

@berbsnicole Ask@my mom how she does it she can finish a book in a snap. I bet she reads 5 or more books a week.

[Buddy the Elf @BuddyTheEllf]

IT’S CHRISTMAS EVE EVE

[Motivational Quotes @motivational]

A powerful thing

[MJ Knepper @mjknepper]

Just taking a moment to take in the beauty of all that surrounds me!! ❤️