Morgane Butler

Postdoctoral Researcher | Neurobiology | @BU_CTE ➡️ Eli Lilly🧠🔬🧪🥼

[Morgane Butler @mo_but]

Ecstatic to bring you our lab's new preprint of my second first author paper and the bulk of my thesis work examining the effects of repetitive head impacts in young individuals who played contact sports. @bu_cte
🧵to follow for a run-through! 👇 1/n
https://t.co/vcokiGDfFK

[nature @Nature]

Repetitive head impacts trigger neuronal loss and disrupt blood vessels and immune cells long before the accumulation of neurotoxic tau protein

https://t.co/oFi3VVb7jr

[Morgane Butler @mo_but]

A big thanks to the team @bu_cte and @joncherry86 for your support though this work and to @BachstetterLab and @Morganti_Lab for your article summarizing the paper which you can read here!

https://t.co/krOqmgwAW2

[Morgane Butler @mo_but]

Excited to share that my thesis work in now published! @Nature @bu_cte

We investigated the earliest responses following repeated head trauma in athletes and found significant neuronal loss, microglial inflammation, and vascular damage.

https://t.co/YdMcRnwd1k

[Morgane Butler @mo_but]

@LukensJohnR @Nature Thanks for sharing our work!

[Morgane Butler @mo_but]

@KenjiEricLee 😬😬😬

[Morgane Butler @mo_but]

*opens dissertation, find and replace “subconcussive” ➡️ “nonconcussive” *

Important editorial by @ChrisNowinski1 and @DanDaneshvar helping us reshape our language regarding head impacts in the absence of concussion.
@bu_cte

[Dan Daneshvar, MD, PhD @DanDaneshvar]

Many hits that don't cause concussions are harder than the hits that do

We should be calling these hits "nonconcussive"

"Subconcussive" makes them sound smaller. They're not

[bioRxiv Neuroscience @biorxiv_neursci]

Repetitive head impacts induce neuronal loss and neuroinflammation in young athletes https://t.co/Q6dl74sqdN #biorxiv_neursci

[Morgane Butler @mo_but]

@SaterAmy Thank you!

[Morgane Butler @mo_but]

Ecstatic to bring you our lab's new preprint of my second first author paper and the bulk of my thesis work examining the effects of repetitive head impacts in young individuals who played contact sports. @bu_cte
🧵to follow for a run-through! 👇 1/n
https://t.co/vcokiGDfFK

[Morgane Butler @mo_but]

This work is the product of a village, I owe a massive thank you to @joncherry86 @annmckeemd @petraypsilantis Ray Nicks, Liz Spurlock, our collaborators Dr. Josh Campbell, Nida Pervaiz, Sarah Mazilli, Julia Breda, Dr. Marco Hefti, and many others. 14/n

[Morgane Butler @mo_but]

Across the cell types discussed we see significant changes in RHI-exposed individuals regardless of CTE status, suggesting cellular changes begin long before disease onset. There is lots more that I can’t get to here so please feel free to reach out to me with questions! 13/n