ANRF-NPDF|Clinical Microbiologist|TB & AMR Research|CNS-TB Biomarker & Drug Discovery|Translational Scientist|Preclinical Model Innovator|Triple Gold Medalist
We've Xplord crystal engineering to up the performance of existing ATDs. Engineered INHsalts with naphthalene disulfonic acid showing 5-20× higher solubility and strong anti-TB activity (MIC0.5–1 µg/mL). | Crystal Growth & Design https://t.co/ovtxfvAS9Z
#tb#DrugDiscovery
This was it;all these years, just a walk.
We walked & we talked
through standardizing protocols,
discussing results,
decoding interpretations,
celebrating papers,
and battling editors.
And now,
this beautiful walk comes to an end.
Thank you, Dr. Zahoor A. Parry
I owe you a lot.
Honored to receive ANRF National Post-Doctoral Fellowship @ANRFIndia. Grateful to all my teachers for their guidance over the years. A special note of thanks to Dr. Parry, everyone at ZAP Lab, and Director & admin of @csiriiim for their invaluable support throughout my PhD.
This chart says it all: the more time teens spend on social media, the more likely they are to experience clinically significant depression, and the effect is dramatically worse for girls.
Influencer culture is silently fueling a crisis, triggering anxiety, self-doubt, and emotional distress amongst our young people. It's time educators and parents step up. We need real conversations about self-worth, media literacy, & digital resilience now more than ever.
🧪 New Study | Actinomycetes from Ladakh’s Tso-Kar salt lake show potent activity against M. tb MDR strains. Several isolates had strong bactericidal effects & diverse bioactive compounds.
📖 https://t.co/MC9F8qk15u
#Tuberculosis#Antibiotics#DrugDiscovery#Actinomycetes
🔬 New Review | Rising antifungal resistance in Candida spp. is a major health threat. Azoles face efficacy & toxicity limits. We discuss novel targets, delivery challenges & next-gen antifungals.
📖 https://t.co/fuTazOLI9s
#AntifungalResistance#Candida#DrugDiscovery#Mycology
🧠Just published! Our latest review unpacks the role of MMP-9 in CNS infections, from disrupting the BBB to serving as a biomarker. Targetting MMP-9 may reshape how we treat neuroinflammation!
Read here: [https://t.co/dloXj1dg4L]
#CNSinfections#MMP9#Neuroinflammation
🚨Update in TB Research🚨
Compounds 7 & 14 show potent activity against DS, INH-R, & MDR M. tb!
✅ Synergistic with INH & RIF
✅ Low toxicity & intracellular efficacy
✅ Superior InhA binding, including resistant mutants
🔗https://t.co/aClzfnZKvW
#MDRTB#DrugDiscovery
Happy to share our research on a rapid CNS-TB model using Sonic Hedgehog (SHH) pathway modulation. This approach could boost drug discovery for CNS tuberculosis. Thanks to our incredible team! #CNSResearch#TB#DrugDiscovery#CNSResearch#DrugDiscovery
https://t.co/0MuxRD5rk8