Phenobarbital is effective for alcohol withdrawal.
But is it safe?
YES!
At VA Boston, we found that SAEs happened in 1 of 244 hospitalizations (0.4%).
There were ZERO:
- intubations
- ICU transfers for over-sedation
- deaths
https://t.co/PsjwdvOGzK
Kudos to @mvronan!
@JoelBoggan@JAM_ASAM@VeteransHealth@gunderson_craig So many great questions left to ask and answer on the topic of alcohol withdrawal management. This look at management in light of the ASAM guideline recommendations gives some insights.
Still a lot of work to do in the field.
Out in @JAM_ASAM-our look across 19 @VeteransHealth🏥for mgt/outcomes for #alcohol#withdrawal led by @mvronan@gunderson_craig
🔹51% symptom-triggered💊alone (⬇️Rx duration)
🔹87%➡️some lorazepam (⬆️duration/complicated w/d)
🔹Delirium = 12.9%, Sz = 4.6%
https://t.co/krYdFzzOkz
Happy Saturday! Is your patient stuck waiting for discharge? They are not alone.
Bann et al: at given time, ~10% pts on gen med services medically stable for DC >1 week (1/2 that: >1 month!)!
⬆️ common @ safety-net 🏥. ~85% pts need DC support.
#VisualAbstract by @CatieGlatz
One of the most important lessons my mentor Kal Gupta taught me was to “keep it simple—“ we used that mantra to develop a feasible & scalable metric for state-wide, real-time pandemic monitoring
With @ShiraDoronMD, our experience in @AnnalsofIM@VA_CHOIR@VABostonHC@VAResearch
Same and next-day appointments available for buprenorphine, opioid withdrawal treatment, overdose prevention/naloxone, harm reduction counseling and equipment, HIV testing (rapid and phlebotomy-based) and #PrEP, linkage to long term care and more.
As fall kicks off want to share contact for Faster Paths, the low-barrier #SUD bridge clinic @GraykenBMC with #Boston#MedTwitter. Faster Paths is open 7 days, 8-4. Call 617-414-4580 or walk in (1 Boston Medical Center Pl, Yawkey 1st Fl) for addiction treatment and #harmreduction
📝 This systematic review summarizes national and international guidelines for management of opioid withdrawal & opioid use disorder, incorporating harm reduction, pain management, and use of non-stigmatizing language for people who use opioids.
⏩ https://t.co/xYnaU80Gjt
@LaurenMerzMD Shorter turnaround, but I read it at the beginning or intern year and at the end of residency and had some similar reactions. Amazing as much as a lot has changed there are still some very deep rooted issues that invoke the same feelings so many years after publication.
In a next step, our team worked to identify risk factors for severe breakthrough infection (which was defined using hospitalization severity metrics)-- summary of these findings is posted here (5/n): https://t.co/d9QdBovSRz @julie_t_wu@JudithStrymish@mvronan
@rbganatra The low rate of pharmacotherapy is unnerving. The health disparity that exists is unacceptable. The data, however, are old (FY2012). It would be enlightening to see if these trends persist with current data. If so the results would be that much more alarming.
@JudithStrymish@tony_breu @BranchWestyn @GaitanisMelissa Things have improved a lot the last few years, but feels like we’re still fighting blind in many ways. Not knowing the variant is one of those ways given the implications on therapeutics.