Some “depression” might be untreated ADHD in disguise.
In a study of 66,146 people with ADHD, adults often used antidepressants before diagnosis.
After ADHD treatment started, antidepressant use fell while it rose in matched controls.
Retatrutide phase 3 obesity trial just came out and the results are genuinely insane:
- 28.3% bodyweight lost on 12mg over 80 weeks
- 70.3 pounds on avg. or 31.9 kg
- 45.3% of patients hit 30%+ weight loss (this is bariatric surgery territory)
- 30.3% weight loss (85 lbs) at 104 weeks in higher-BMI patients
- 65.3% of 12mg patients dropped below the obesity BMI threshold
- 19% loss on 4mg over 80 weeks (47.2 lbs) with fewer dropouts than placebo (4.1% vs 4.9%)
- significant drops in blood pressure, triglycerides, non-HDL cholesterol, waist circumference, and hsCRP
- no cardiac or liver signals
Retatrutide is going to completely overshadow tirzepatide and semaglutide, and take the throne as the best-selling drug of all time.
Los protectores solares que me he puesto son horribles.
Son pegajosos, huelen mal y si sudo cerca de los ojos, me arden.
Los protectores solares tienen disruptores endocrinos que no vale echar en saco roto.
https://t.co/evkaS8osNy
¿Usar crema solar bloquea la vitamina D? ☀️🧴
Un estudio en adultos sanos mostró que una exposición solar leve con SPF30 aumentó la vitamina D prácticamente IGUAL que sin protección solar.
📈 SPF30:
+5.5 ng/ml de vitamina D
📈 Sin crema:
+4.1 ng/ml
Conclusión:
La fotoprotección “real” NO impide una correcta síntesis de vitamina D.
Unpopular opinión: la inteligencia del mexicano si la dictamina en gran parte su alimentación.
El llenarse de carbohidratos fritos y azúcar, en lugar de incrementar la proteína animal genera un declive en la cognición de la gente.
Darles testosterona a las mujeres hace que se comporten de manera más justa y menos conflictiva. Sin embargo, las mujeres que creen que han tomado testosterona —pero que en realidad han tomado placebo— se comportan de manera más agresiva y más injusta.
La dermatología sobrevive por casos de acné que en su mayoría son hormonales a causa de una mala alimentación y también de los patrocinios de bloqueadores solares y de los daños que ocasiona el maquillaje en los poros de las mujeres.
Researchers at the University of Bergen ran a study comparing 213 Sudanese men. Half brushed their teeth with a chewed tree root. Half used a regular plastic toothbrush. The tree root group came out with healthier gums and less plaque.
That stick is called a miswak. The WHO has been quietly recommending it since 1986. In 2011, scientists at Sweden’s Karolinska Institute finally cracked the chemistry.
The active ingredient is benzyl isothiocyanate, a natural plant defense compound from the same family of sulfur molecules that give cabbage and mustard their sharp bite. The compound punches through the outer wall of bacteria that cause gum disease. From there, it dismantles the chemistry that keeps the bacteria alive. The Karolinska team isolated it by running root extracts through a chemical analyzer that identifies individual molecules.
The stick comes from the Salvadora persica tree, which grows in dry parts of Africa, the Middle East, and India. Inside the wood you also find natural fluoride, a gentle abrasive called silica that polishes off plaque, sulfur compounds, and tannins that tighten gum tissue. A separate team at Sweden’s University of Gothenburg ran another trial. They soaked the sticks in a fluoride solution. The fluoride left in the test group’s saliva came out higher than what people got from regular fluoride toothpaste.
A more recent systematic review pulled together a stack of randomized trials. Miswak on its own controlled plaque about as well as a regular toothbrush. Used alongside the toothbrush, it actually beat brushing alone on both plaque and gum inflammation scores. The Princess Nourah University trial from 2024 complicates that. Over two weeks, the miswak group��s plaque held steady while the toothbrush group’s dropped further. And gums in the miswak group got noticeably worse for people who sawed at their teeth too hard. Aggressive horizontal scrubbing tears at the soft tissue along the gum line.
One stick costs under 10 cents in the regions where the tree grows, and a single twig lasts for weeks. In sub-Saharan Africa, herbal toothpastes built around miswak and neem (another bitter chewing-stick tree) made up over a quarter of toothpaste sales in 2023.
The honest caveat is that Western dental literature treats the miswak as an add-on rather than a replacement, mostly because reaching the back molars with a stick is awkward. Used correctly, with soft perpendicular brushing along the gum line and no aggressive sawing, it does what a toothbrush does and adds a low-grade antibiotic on top. For most of human dental history, this is what cleaning your teeth looked like.
In adults, limiting smartphone functionality to texting and calls and blocking all social media and mobile internet for 2 weeks significantly improved attention, self-reported well-being and mental health. 90% of participants experienced a benefit.
Totalmente de acuerdo.
Es perdida del valor adquisitivo, no los sellos y ni siquiera los impuestos que a final de cuentas ya pagaban un IEPS desde el 2014
@AriesTerron Que pena tu análisis 4tero. Es el incremento al costo lo que ha reducido el consumo. Tristemente el consumo de carne ha disminuido igual o más que el de la coca cola. Lo que estás celebrando es la perdida del poder adquisitivo. A ver si en 15 años podemos recuperarlo.
El pensar que antes la gente tenía más testosterona por sesgos en su medición, es negar la mierda de ambiente en el que vivimos actualmente
https://t.co/kAHh2rbqcJ
Antes los hombres tenían más testosterona 🧔🏻♂️📈
❌ Pero la explicación no es tan conspiranoica como “nos están feminizando con químicos y soya”.
⁉️ La evidencia apunta mucho más hacia el entorno moderno: sedentarismo, peor sueño, más grasa corporal, estrés crónico, alcohol y hábitos deficientes.
💪🏼 Si quieres favorecer niveles saludables de testosterona, probablemente te ayude más corregir eso que obsesionarte con comer 30 huevos al día.