To all antibody (or ADC) experts:
Approx. what percent of a single injected dose hit the target site (e.g., tumor) in human?
Or do we at least have this information in NHP or mice/rats?
#antibody#ADC#invivo#oncology
Just reading this. Great piece by @matthewherper about how we have to move as a whole to really make this the biology’s century. https://t.co/ybYZwCqI79 - @statnews
Congratulations for Jeonghwan Kim (David) and team for this work that came out @acsnano . David persistence paid off as he made LNPs fly to deliver large genes. Thx to @nih_nhlbi @LachowiczMarrah @NHLBI_LUNGDir and @CF_Foundation for supporting us.
https://t.co/vcrEnUbSYt
Inhaled gene therapy of preclinical muco-obstructive lung diseases by nanoparticles capable of breaching the airway mucus barrier https://t.co/pEdUVQqgbO