(ORIGINAL) microRNA-based predictor for diagnosis of frontotemporal dementia
https://t.co/aOzO32ROwR
Using cell-free plasma #miRNA profiling, a model was developed to accurately distinguish frontotemporal #dementia from non-neurodegenerative controls in about 90% of cases.
(ORIGINAL) Is Islet Amyloid Polypeptide indeed expressed in the human brain?https://t.co/7Uh94K3hRP
No specific expression of islet amyloid polypeptide (IAPP) in human brain tissue was found, suggesting no direct link between IAPP and Alzheimer's Disease Neuropathological Change.
(Review) Intelligence quotient–genotype association in dystrophinopathies: A systematic review and meta-analysis
https://t.co/ogxSwlFDN4
Becker and Duchenne muscular dystrophies associate with lower IQs, which inversely correlate with the number of affected dystrophin isoforms.
(Review) Timing is everything: A connection between medulloblastoma prognosis and foetal cerebellar development
https://t.co/DDu1gi6b1a
Survival in non-WNT/non-SHH #medulloblastoma is continuously linked to tumour transcriptional profile and foetal cerebellar development stage.
(Original) Increased number and domain of interlaminar astrocytes in layer I of the temporal cortex in epilepsy
https://t.co/T8nPMZCZSj
Astrocytic structural remodeling in layer I of the temporal cortex may play a significant role in #epilepsy.
Original, Open access,
TDP-43 pathology and functional deficits in wild-type and ALS/FTD mutant cyclin F mouse models
https://t.co/j3wrOQf2mu
Mouse models expressing human #CCNF variants mirrored behavioral abnormalities and neuropathological hallmarks of #ALS and #FTD.
Original, Open access,
Occurrence of focal myositis during #Behçet's disease: The identification of a specific vasculitis-associated focal myopathy
https://t.co/zolpHyEDNp
Focal myositis in Behçet's disease indicates systemic vasculitis, needing special care.
(Original) Patient-derived xenograft mouse models to investigate tropism to the central nervous system and retina of primary and secondary central nervous system lymphoma
https://t.co/lFq7qclNB6
An in vivo model provide a basis for studying therapeutic targets for #CNS#lymphoma.
ORIGINAL
Schwann cells and myelin in human peripheral nerve: Major protein components vary with age, axon size and pathology. https://t.co/H3SL2QW3Ee
Protein components in Schwann cells and myelin vary with age, axon size, and nerve pathology, influencing peripheral nerve health.
(Short communication, Open Access)
Motor neuron involvement threatens survival in spinocerebellar ataxia type 1
https://t.co/v1XIbNEYta
Severe laryngeal dysfunction is the key life-threatening condition in #SCA1 due to significant motor neuron loss.
(ORIGINAL) Robust #methylation-based classification of brain tumours using nanopore sequencing
https://t.co/w4etlgYdUo
Nanopore sequencing enables rapid, cost-effective DNA methylation-based brain tumor classification with high accuracy and specificity.
(ORIGINAL) Discrepant modulating effects of dietary #docosahexaenoic acid on cerebral lipids, fatty acid transporter expression and soluble beta-amyloid levels in ApoE−/− and C57BL/6J mice
https://t.co/1nnOPTx9Ld
(ORIGINAL) Axonal response of #mitochondria to #demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis
https://t.co/bMsmEDqazI
axon response of mitochondria to demyelination, highlighting potential for neuroprotective therapy
(SHORT COMMUNICATION) Structural synaptic signatures of #Alzheimer's disease and dementia with Lewy bodies in the male brain https://t.co/Tk6SAtbZ3F
Confocal microscopy reveals alterations in synaptic organization in the brain sample associated with neurodegeneration in dementia
(ORIGINAL ARTICLE) Target formation in muscle fibres indicates reinnervation – A proteomic study in muscle samples from peripheral neuropathies
https://t.co/5OAQ8Gl4DT
(ORIGINAL) Myostatin in idiopathic inflammatory myopathies: Serum assessment and disease activity. https://t.co/anMUpmCkvy
Myostatin levels lower in IIM; inactive ASyS and DM have higher myostatin; in IMNM, low myostatin levels persist, indicating a new pathological mechanism.