NAN

International Journal: Neuropathology and Applied Neurobiology

[NAN @NAN_Wiley]

(ORIGINAL) microRNA-based predictor for diagnosis of frontotemporal dementia
https://t.co/aOzO32ROwR
Using cell-free plasma #miRNA profiling, a model was developed to accurately distinguish frontotemporal #dementia from non-neurodegenerative controls in about 90% of cases.

[NAN @NAN_Wiley]

(ORIGINAL) Is Islet Amyloid Polypeptide indeed expressed in the human brain?https://t.co/7Uh94K3hRP
No specific expression of islet amyloid polypeptide (IAPP) in human brain tissue was found, suggesting no direct link between IAPP and Alzheimer's Disease Neuropathological Change.

[NAN @NAN_Wiley]

(Review) Intelligence quotient–genotype association in dystrophinopathies: A systematic review and meta-analysis
https://t.co/ogxSwlFDN4
Becker and Duchenne muscular dystrophies associate with lower IQs, which inversely correlate with the number of affected dystrophin isoforms.

[NAN @NAN_Wiley]

(Review) Timing is everything: A connection between medulloblastoma prognosis and foetal cerebellar development
https://t.co/DDu1gi6b1a
Survival in non-WNT/non-SHH #medulloblastoma is continuously linked to tumour transcriptional profile and foetal cerebellar development stage.

[NAN @NAN_Wiley]

(Original) Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers High-Grade Gliomas (HGG)
https://t.co/0C2J424Yy6
Simultaneous inactivation of #Nbs1 and #p53 in mice promotes high-grade #gliomas, mimicking Radiation-Induced Gliomas.

[NAN @NAN_Wiley]

(Original) Increased number and domain of interlaminar astrocytes in layer I of the temporal cortex in epilepsy
https://t.co/T8nPMZCZSj
Astrocytic structural remodeling in layer I of the temporal cortex may play a significant role in #epilepsy.

[NAN @NAN_Wiley]

Original, Open access
Tuberous sclerosis complex-1 (TSC1) contributes to selective neuronal vulnerability in Alzheimer's disease
https://t.co/KRDiOIRVo8
#TSC1 dysregulation may drive selective neuronal vulnerability in #Alzheimer's disease, highlighting potential therapeutics.

[NAN @NAN_Wiley]

Original, Open access,
TDP-43 pathology and functional deficits in wild-type and ALS/FTD mutant cyclin F mouse models
https://t.co/j3wrOQf2mu
Mouse models expressing human #CCNF variants mirrored behavioral abnormalities and neuropathological hallmarks of #ALS and #FTD.

[NAN @NAN_Wiley]

Original, Open access,
Occurrence of focal myositis during #Behçet's disease: The identification of a specific vasculitis-associated focal myopathy
https://t.co/zolpHyEDNp
Focal myositis in Behçet's disease indicates systemic vasculitis, needing special care.

[NAN @NAN_Wiley]

(Original) Patient-derived xenograft mouse models to investigate tropism to the central nervous system and retina of primary and secondary central nervous system lymphoma
https://t.co/lFq7qclNB6
An in vivo model provide a basis for studying therapeutic targets for #CNS #lymphoma.

[NAN @NAN_Wiley]

ORIGINAL
Schwann cells and myelin in human peripheral nerve: Major protein components vary with age, axon size and pathology. https://t.co/H3SL2QW3Ee
Protein components in Schwann cells and myelin vary with age, axon size, and nerve pathology, influencing peripheral nerve health.

[NAN @NAN_Wiley]

(Short communication, Open Access)
Soluble amyloid-β dimers are resistant to amyloid-β prion conversion in vivo suggesting antiprion properties
https://t.co/vXLx1Kib47
Aβ dimers inhibit Aβ prion spreading in vivo, potentially counteracting Aβ aggregation.

[NAN @NAN_Wiley]

(Short communication)
Fibrocartilaginous cerebral and spinal emboli: A report of two cases with histopathological confirmation
https://t.co/yGtCKDplrl

[NAN @NAN_Wiley]

(Short communication, Open Access)
Motor neuron involvement threatens survival in spinocerebellar ataxia type 1
https://t.co/v1XIbNEYta
Severe laryngeal dysfunction is the key life-threatening condition in #SCA1 due to significant motor neuron loss.

[NAN @NAN_Wiley]

(ORIGINAL) Robust #methylation-based classification of brain tumours using nanopore sequencing
https://t.co/w4etlgYdUo
Nanopore sequencing enables rapid, cost-effective DNA methylation-based brain tumor classification with high accuracy and specificity.

[NAN @NAN_Wiley]

(ORIGINAL) Discrepant modulating effects of dietary #docosahexaenoic acid on cerebral lipids, fatty acid transporter expression and soluble beta-amyloid levels in ApoE−/− and C57BL/6J mice
https://t.co/1nnOPTx9Ld

[NAN @NAN_Wiley]

(ORIGINAL) Axonal response of #mitochondria to #demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis
https://t.co/bMsmEDqazI
axon response of mitochondria to demyelination, highlighting potential for neuroprotective therapy

[NAN @NAN_Wiley]

(SHORT COMMUNICATION) Structural synaptic signatures of #Alzheimer's disease and dementia with Lewy bodies in the male brain https://t.co/Tk6SAtbZ3F
Confocal microscopy reveals alterations in synaptic organization in the brain sample associated with neurodegeneration in dementia

[NAN @NAN_Wiley]

(ORIGINAL ARTICLE) Target formation in muscle fibres indicates reinnervation – A proteomic study in muscle samples from peripheral neuropathies
https://t.co/5OAQ8Gl4DT

[NAN @NAN_Wiley]

(ORIGINAL) Myostatin in idiopathic inflammatory myopathies: Serum assessment and disease activity. https://t.co/anMUpmCkvy
Myostatin levels lower in IIM; inactive ASyS and DM have higher myostatin; in IMNM, low myostatin levels persist, indicating a new pathological mechanism.