Top Tweets for #SCA1
Exciting news! @AtaxiaUK's project reveals SMaRT gene therapy's potential for SCA1 by targeting toxic Ataxin 1. Read more: https://t.co/LDwauG9cnZ #AtaxiaResearch #Ataxia #CerebellarAtaxia #SCA1 #SCA #SpinocerebellarAtaxia #UniversityOfNorthampton
Today #SCA1 patient representative Klaas Russcher and I were guests at the #INVOLV podcast about patient participation in translational research. We were interviewed by @IngeDiepman and Simone Harmsen about collaboration between patients and researchers/health care professionals.
The Assembly Elections Committee passed SCA 1, a constitutional amendment to simplify and reform California's recall process. Thank you to Secretary of State Dr. Shirley Weber and Dora Rose from the League of Women Voters for their testimony!
#SCA1 simplifies a statewide recall into one question: should this person be removed from office? If the voters choose to remove an official, the newly vacant position would be filled in the same manner as if the official had resigned or was otherwise removed from office.
This upholds the integrity of our election system while still allowing voters to hold public officials accountable.
The amendment continues to move through the Legislature before being presented to all California voters for approval. #caleg
🎉@LWVC's co-sponsored bill #SCA1 moved to the Assembly with bipartisan support today! @JoshNewmanCA thanks for your leadership to simplify confusing CA recall elections & reduce the risk of abuse by special interests. Read our support letter for details: https://t.co/T3MMaYK5JJ
#SCA1 PASSES to Asm.
The two-vote ballot (recall Y/N and successor) has been criticized as undemocratic. "No" on recall can get more votes than successor
But also consider top R vote-getter @larryelder was a big boost to @GavinNewsom. Different election w/o Elder to run against
Our neuroscientists uncovered all kinds of secrets of the brain last year, from visualizing axonal transport to investigating neurodegenerative diseases such as #SCA1 & #Parkinsons. Readers had a few favorites.
Here are our top 3 science stories of 2023😮:
https://t.co/Qmii45hBXy
Scott Schobel, MD, Chief Medical Officer at Vico Therapeutics, discusses current treatment options for Huntington’s disease and spinocerebellar ataxia #SCA1 #SCA3 #checkrare @HDA_tweeting @DiseaseAwarenes
https://t.co/9rkAJEjR71
ICYMI: A human-specific protein may be driving dynamic DNA changes, affecting people with neurodegenerative conditions. 🧠
The #SKResearch in @CellCellPress suggests this protein may present a new therapeutic target for #Huntingtons and #SCA1.
https://t.co/3NSt14na4q
A human-specific protein may be driving dynamic DNA changes, affecting people with neurodegenerative conditions. 🧬🧠
The #SKResearch in @CellCellPress suggests this protein may present a new therapeutic target for #Huntingtons and #SCA1.
Read ➡️ https://t.co/3NSt14na4q
Just out in @hmg_journal: we utilize bulk RNAseq to demonstrate dysregulation of🧬alternative splicing🧬in spinocerebellar ataxia type 1 #SCA1
Congratulations to our grad student Victor Olmos and additional authors who contributed to this work!🎉
https://t.co/BI43hLSsHX
Scott Schobel, MD, chief medical officer at Vico Therapeutics, discussed the latest data testing an antisense therapy to treat Huntington’s disease and spinocerebellar ataxia type 1 #SCA1 and type 3 #SCA3 #checkrare @HDA_tweeting
https://t.co/ra1SbUE3XG
Scott Schobel, MD, chief medical officer at Vico Therapeutics, discussed the latest data testing an antisense therapy to treat Huntington’s disease and spinocerebellar ataxia type 1 #SCA1 and type 3 #SCA3 #checkrare @HDA_tweeting
https://t.co/ra1SbUDw88
Congratulations Smita Saxena, @liebscher_lab and teams!
Very happy with our small contribution to this @NeuroCellPress paper presenting new evidence for early cerebellar circuit-related dysfunction in #SCA1!
Happy to share our latest publication. We identified hyperexcitable cerebellar molecular layer interneurons as a key driver of purkinje neuron degeneration in spinocerebellar ataxia. Circuits matter in neurodegeneration.
https://t.co/JLfqR57jG5
Today are the therapeutics sessions at the @GordonConf #CAG triplet repeat meeting. Looking forward to hear about many aspects that @LaurieKerkhof covered in her recent review on #SCA1 therapeutics!
https://t.co/MzicPbVraP
Happy to announce that our @NeuroD_Lab_LUMC paper on the identification of SCA1-relevant phenotypes in patient-specific fibroblasts and #SCA1 induced pluripotent stem cells (iPSCs) neuronal cultures is published in @MDJ_Journal!
@roon_mom
https://t.co/nieNlCzSvY
Elsa will present her SCA3 ASO work in a 15 min. talk and her HD work on a poster. Linde (#SCA3) and @LaurieKerkhof and @BuijsenRonald (both #SCA1) will present their work during the poster session. Happy to discuss our work with a coffee or beer.
Therapeutic Strategies for Spinocerebellar Ataxia Type 1 (#SCA1), an autosomal dominant neurodegenerative disorder that affects one or two individuals per 100,000
#mdpibiomolecules @Biomol_MDPI
https://t.co/eVpcQLMVB6
Fantastic start to @CAN_ACN with yesterday’s #cerebellum satellite. Big thanks to @jillumine for introducing me to this welcoming community, organizers @alanna_j_watt & @SynapticTweeter for an amazing session with much great science. Excited to embark on our #SCA1 project!
Congrats @LaurieKerkhof with your review on #SCA1 therapeutics. And many thanks to co-authors @roon_mom (@NeuroD_Lab_LUMC, @GlobalLumc) and Bart van Warrenburg (@radboudumc).
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