Using label-free #biosensors we determined the effect of fluid flow on cellular adhesion. This new method can be used to examine the response of cells to drugs or treatments as a function of the flow field. 🌊🧫
https://t.co/waMXEeb0Hl
Take a look at the top 100 most downloaded papers in @SciReports
in 2020: https://t.co/lJ1rRsNs45
Happy to see our paper about kinetic cell adhesion measurements calibrated by #FluidFM in the top25.
👨🔬👩🔬📈 https://t.co/bgVwspjMJy
We are ending our #WomensHistoryMonth campaign on a high note with #Hungary!
🇭🇺 Biochemist Dr. Katalin Karikó has spent more than 40 years researching the therapeutic possibilities of mRNA, a component of DNA. Today, her work is the basis of the #COVID19 vaccine. #EU4Women
https://t.co/DnlsyQEYjC
Carboxymethyl dextran is a promising material to control cell adhesion properties. In this paper we give a full characterization of its mechanical properties, measured by OWLS and QCM #biosensors.
Beneficial health effects of #greentea are known for centuries, but the molecular mechanisms in the background are still being investigated. Here, using label-free #biosensors we investigated how EGCG and its oxidized version can influence cell adhesion
https://t.co/IH1i8LTtx3
In this 2014 paper in @SciReports, we investigated the dependence of cell adhesion on the distance of RGD ligands. Optical #biosensor data made it possible to record #kinetic adhesion curves, and to determine the dissociation constant as well!
https://t.co/O0DNOfqi6d
One of the most exiting areas in cell adhesion research is the role of the glycocalyx, this complex web of large extracellular molecules surrounding cells. Learn more on how #biosensors helped discover the critical role of this structure in cell adhesion!
https://t.co/jwoBYht1CK
@ZbyszekBaster Very interesting results! Would be interesting to see what's the case for larger, 10 um beads that have a smaller radius of curvature, maybe this effect is mitigated?
Check out our latest paper on Ni ion binding on genetically engineered protein surfaces! Measuring the #kinetics of a 60 Da compound has certainly been a challenge. #biophysics#molecular#chemistry
https://t.co/TUFROhAGHS
Stop scrolling Twitter to watch this unbelievable video of a baby water bear hatching from its egg and crawling into the world! #WaterBearWednesday
Credit: Hunter Hines
Bacteria biofilms are the driving engine in biofilm-reactors e.g. to produce ethanol. In this study researchers from the University of Kaiserslautern apply FluidFM to study bacterial adhesion to typical reactor material such as stainless steel. https://t.co/7ReKU9orU2
A very exciting study by our friends at @umontpellier demonstrating a simple and efficient novel methodology for simultaneous visualization of luminescent fND probes and cell nucleus utilizing confocal PL/Raman imaging.
https://t.co/yjly4QHUm3
One of our all-times favorites!⠀
A pre-adipocyte cell imaged with #Nanolive's label-free microscope.⠀
⠀
You can appreciate:⠀⠀
*healthy mitochondria⠀⠀
*lipid vesicles (small white dots)⠀⠀
*nucleoli in the dynamic nucleus⠀⠀
*intricate membrane ruffles⠀⠀
*filopodia
Multiplexed #CRISPR is definitely something to look out for! Multiple knockout cell lines are expected to greatly accelerate the development of #disease models, therefore #therapeutics as well.
Triple KO clones of CHO cells in less than 2 weeks! 50 cells were co-injected with three different gRNA/Cas9 RNP complexes, delivered directly into the nucleus. #crispr#geneediting More details on the use case: https://t.co/Ky1Oj6OOuE