Nanobiosensorics Laboratory

Nanobiosensorics Laboratory at the Centre for Energy Research, Budapest 🇭🇺
Label-free biosensors 🔬 single-cell manipulations 🔭molecular interactions 🧫

[Nanobiosensorics Laboratory @nanobiosensorix]

Using label-free #biosensors we determined the effect of fluid flow on cellular adhesion. This new method can be used to examine the response of cells to drugs or treatments as a function of the flow field. 🌊🧫

https://t.co/waMXEeb0Hl

[Nanobiosensorics Laboratory @nanobiosensorix]

Take a look at the top 100 most downloaded papers in @SciReports
in 2020: https://t.co/lJ1rRsNs45
Happy to see our paper about kinetic cell adhesion measurements calibrated by #FluidFM in the top25.
👨‍🔬👩‍🔬📈 https://t.co/bgVwspjMJy

[Nanobiosensorics Laboratory @nanobiosensorix]

@LUMICKS_nl This would be perfect to measure immune cell avidity on the go 🙏🚅 no need to wait for getting to the lab🚎

[Nanobiosensorics Laboratory @nanobiosensorix]

@Maurice_Y_Lee @SingleCellMedia Love the name 😅👌

[European Union in the U.S. @EUintheUS]

We are ending our #WomensHistoryMonth campaign on a high note with #Hungary!

🇭🇺 Biochemist Dr. Katalin Karikó has spent more than 40 years researching the therapeutic possibilities of mRNA, a component of DNA. Today, her work is the basis of the #COVID19 vaccine. #EU4Women

[Nanobiosensorics Laboratory @nanobiosensorix]

https://t.co/DnlsyQEYjC
Carboxymethyl dextran is a promising material to control cell adhesion properties. In this paper we give a full characterization of its mechanical properties, measured by OWLS and QCM #biosensors.

[CytoSurge AG @cytosurge]

Congratulations on this impressive work, where #FluidFM technology is used to perform cytoplasmic #mRNA #biopsies for #liveseq analysis, a unique approach enabling consecutive #transcriptomic analyses of a #singlecell.

[Nanobiosensorics Laboratory @nanobiosensorix]

@PROXIMA_1 @dcz_92 @institutpasteur @DECTRIS_News @synchroSOLEIL Congrats Dariusz!

[Katalin Kariko @kkariko]

Today, I was awarded the Széchenyi Prize by the Hungarian Government in recognition of my scientific contribution to fight the corona virus pandemic.

[Nanobiosensorics Laboratory @nanobiosensorix]

Beneficial health effects of #greentea are known for centuries, but the molecular mechanisms in the background are still being investigated. Here, using label-free #biosensors we investigated how EGCG and its oxidized version can influence cell adhesion
https://t.co/IH1i8LTtx3

[Nanobiosensorics Laboratory @nanobiosensorix]

In this 2014 paper in @SciReports, we investigated the dependence of cell adhesion on the distance of RGD ligands. Optical #biosensor data made it possible to record #kinetic adhesion curves, and to determine the dissociation constant as well!

https://t.co/O0DNOfqi6d

[Nanobiosensorics Laboratory @nanobiosensorix]

One of the most exiting areas in cell adhesion research is the role of the glycocalyx, this complex web of large extracellular molecules surrounding cells. Learn more on how #biosensors helped discover the critical role of this structure in cell adhesion!
https://t.co/jwoBYht1CK

[Nanobiosensorics Laboratory @nanobiosensorix]

@ZbyszekBaster Or to combine the system with AFM or FluidFM based colloidal force microscopy to reveal the dependence on external force.

[Nanobiosensorics Laboratory @nanobiosensorix]

@ZbyszekBaster Very interesting results! Would be interesting to see what's the case for larger, 10 um beads that have a smaller radius of curvature, maybe this effect is mitigated?

[Nanobiosensorics Laboratory @nanobiosensorix]

Check out our latest paper on Ni ion binding on genetically engineered protein surfaces! Measuring the #kinetics of a 60 Da compound has certainly been a challenge. #biophysics #molecular #chemistry
https://t.co/TUFROhAGHS

[Nanobiosensorics Laboratory @nanobiosensorix]

Amazing content!

[Evident Life Science @Evident_LS]

Stop scrolling Twitter to watch this unbelievable video of a baby water bear hatching from its egg and crawling into the world! #WaterBearWednesday

Credit: Hunter Hines

[CytoSurge AG @cytosurge]

Bacteria biofilms are the driving engine in biofilm-reactors e.g. to produce ethanol. In this study researchers from the University of Kaiserslautern apply FluidFM to study bacterial adhesion to typical reactor material such as stainless steel. https://t.co/7ReKU9orU2

[Nanobiosensorics Laboratory @nanobiosensorix]

A very exciting study by our friends at @umontpellier demonstrating a simple and efficient novel methodology for simultaneous visualization of luminescent fND probes and cell nucleus utilizing confocal PL/Raman imaging.

https://t.co/yjly4QHUm3

[Nanolive @NanoLiveLtd]

One of our all-times favorites!⠀
A pre-adipocyte cell imaged with #Nanolive's label-free microscope.⠀
⠀
You can appreciate:⠀⠀
*healthy mitochondria⠀⠀
*lipid vesicles (small white dots)⠀⠀
*nucleoli in the dynamic nucleus⠀⠀
*intricate membrane ruffles⠀⠀
*filopodia

[Nanobiosensorics Laboratory @nanobiosensorix]

Multiplexed #CRISPR is definitely something to look out for! Multiple knockout cell lines are expected to greatly accelerate the development of #disease models, therefore #therapeutics as well.

[CytoSurge AG @cytosurge]

Triple KO clones of CHO cells in less than 2 weeks! 50 cells were co-injected with three different gRNA/Cas9 RNP complexes, delivered directly into the nucleus. #crispr #geneediting More details on the use case: https://t.co/Ky1Oj6OOuE