.@GoogleDeepMind are you planning to release #AlphaGenome predictions for each 1Mb bin of the human genome at some point?
It would be great to have them in @ensembl or @ucsc genome brower.
(Similarly to AlphaFold predictions for all proteins on UniProt)
Thanks!
Earlier this year, I learned I have a pathogenic variant in BRCA2, which gives me a very high lifetime risk of breast cancer (55-69%), as well as an increased risk of ovarian cancer (12-29%) and pancreatic cancer (5-10%).
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Excited to share that the AlphaFold 3 model code and weights are now available for academic use.
Looking forward to seeing what new research this unlocks and how the research community builds on AlphaFold 3 for scientific discoveries https://t.co/GKIOGHm317 1/2
Xciting news + Jobs alert! 🚨 After wonderful years at @CRGenomica, we are relocating beginning 2025 to @ChuSteJustine at @UMontreal. If you want to be part of @payerlab 2.0, come and join us! We are hiring at all levels – see job ads in the thread 🧵below. 👇 1/5
@marcotrizzino You can get them from an ENSEMBL GTF file:
wget https://t.co/ejVapng2xI
zcat Homo_sapiens.GRCh38.112.gtf.gz | head -n 150 | grep -v "^#" | grep "exon" | cut -f 1,4-7 | uniq
Of course there'll a lot of crap in it
We love the excitement & results from the community on AlphaFold 3 and are doubling the AF Server daily job limit to 20. Happy to also share that we're working on releasing the AF3 model (incl weights) for academic use, which doesn’t depend on our research infra, within 6 months.
Announcing AlphaFold 3: our state-of-the-art AI model for predicting the structure and interactions of all life’s molecules. 🧬
Here’s how we built it with @IsomorphicLabs and what it means for biology. 🧵 https://t.co/gjw6Ip4F2M
Very happy to see our work on the unexpected role of splicing in regulating Polycomb assembly, occupancy, dimerization and histone mark deposition.
Great team work with @mirimiam, @NccAcc, @Ivuaenneo, among others! https://t.co/TroEDeR1w2