Adonis Yiannakas

Faculty Lecturer @EuropeanUniCy Frankfurt
Neuroscience, neuroimmunology, pharmacology

[Adonis Yiannakas @neuradon13]

What if you could use light to switch off specific receptors in a tiny part of the brain without genetic engineering? New work demonstrates exactly that in zebrafish, with lasting effects on behavior https://t.co/L86NcVQgie

[Adonis Yiannakas @neuradon13]

How does a sensory cue come to predict what will happen inside the body hours later?
In our new Trends in Neurosciences review, we examine how the insular cortex links sensory experience to predicted bodily states. @SailendKc @Neurosenblum @KobiRosenblum https://t.co/BMuWOLaysQ

[Adonis Yiannakas @neuradon13]

Interesting paper proposing a theory in which consciousness and intelligence emerge from increasingly complex layers of self-representation in living systems. From broad philosophy toward testable links between neural organization, behavior, and evolution.https://t.co/QlJ5Wlem04

[Adonis Yiannakas @neuradon13]

A useful reminder for behavioral phenotyping: integrating multi-assay data is important, but broad domain composites may also dilute localized effects. In this aging dataset, the strongest signals remained assay-specific.
https://t.co/0cwTux9CCA

[Adonis Yiannakas @neuradon13]

A novel open-source system enables hi-res microstructure analysis of licking in mice
• Dissociates innate vs. learned aversion
• Beyond cumulative consumption assays
• Reveals unique signatures for appetitive, aversive & neutral tastants
@Neurosenblum
https://t.co/4YMo6MeO5l

[Reymond Group @reymondgroup]

🎊Check out our latest publication "Exploring Simple Drug Scaffolds from the Generated Database Chemical Space Reveals a Chiral Bicyclic Azepane with Potent Neuropharmacology" in Journal of the Medicinal Chemistry!
Read the full version here👉https://t.co/VYLAEUCblA
@DCBPunibern

[Adonis Yiannakas @neuradon13]

Our latest research on ERK1/2 nuclear translocation in extinction learning is now published! We used viral-mediated peptide delivery to block nuclear ERK1/2 selectively. ERK1/2 nuclear translocation is critical for memory extinction. @lab_rosenblum
https://t.co/cj4P1PWHTJ

[Adonis Yiannakas @neuradon13]

Thrilled to share our latest research on intra-insular circuits and their role in immune regulation and memory! We reveal how brain circuits encode immune memories, offering new insights into neuroimmune communication and how the brain can shape immunity. https://t.co/Eq3TREUUO0

[Adonis Yiannakas @neuradon13]

Last week's new beginnings at EUC Medical School in Frankfurt
@EuropeanUniCy

[Adonis Yiannakas @neuradon13]

New insights into insular interhemispheric circuits! 🧠 Neurons, crucial for social behavior, become hyper-excitable after 24h of social isolation in male mice. These unmyelinated neurons connect with the CeA and BNST, playing a key role in social behavior https://t.co/31CpRKsT9p

[Adonis Yiannakas @neuradon13]

Looks like ethanol-driven taste aversion memories also rely on parvalbumin inhibition on insular cortex neurons projecting to the amygdala. https://t.co/mCSV9cBgzv

[Open Research, University of Dundee @UoDOpenResearch]

🔓#OA
Central deficiency of IL-6Ra in mice impairs glucose-stimulated insulin secretion
➡️https://t.co/6EHxLiyBwC
@UoDMedicine @ad_mcneilly @neuradon13 J Gallagher @JamieTarlton Prof M Ashford, Prof R McCrimmon
#Interleukin6 #FoodIntake #EnergyExpenditure #InsulinSecretion

[Adonis Yiannakas @neuradon13]

Grateful to for the opportunity and proud to be part of the development of @Synendos. Brief communication on the endocannabinoid Odyssey to the Ithaca of drug development

https://t.co/el4hlHsTzb

[Adonis Yiannakas @neuradon13]

Using retrograde viral tracing, behavioral analysis, and electrophysiology at the insular cortex, we reveal that the intrinsic properties of BLA-projecting neurons are regulated by innate and learned drives, as a function of certainty of taste valence prediction, but not percept.

[bioRxiv Neuroscience @biorxiv_neursci]

Intrinsic excitability in layer IV-VI anterior insula to basolateral amygdala projection neurons encodes the confidence of taste valence https://t.co/cTvT2pHSU0 #biorxiv_neursci

[Adonis Yiannakas @neuradon13]

Ten years and two countries later, my PhD research at the @dundeeuni is now published @MolMetab !
#metabolism #inflammation #cytokines #insulin

https://t.co/JJfTPOum2I

[Cell @CellCellPress]

Online now! Brain-wide neuronal imaging of C. elegans shows that correlations of activity between functionally unique neurons are not fixed, but depend on behavioral context
#neuroscience
https://t.co/DztLIedvUU

[Adonis Yiannakas @neuradon13]

Quinone reductase-2 mediated intrinsic property changes of SST interneurons in the aIC is a central removable factor to allow novel taste memory formation. @Neurosenblum
https://t.co/ZiFQvv7iAT

[Adonis Yiannakas @neuradon13]

Interesting new review on the role of interneurons in sleep and memory processes @UMich_MCDB
https://t.co/WJzPXeeo7D

[koenv @koen_vervaeke]

We patched the dendrites of PV+ basket cells in the hippocampus and found that sub-linear integration dramatically enhances neural synchrony during gamma oscillations. Finally out after 5 years in development.
https://t.co/1qzMcysYF9

[Adonis Yiannakas @neuradon13]

So this is now officially out! Our studies @Neurosenblum demonstrate how interactions between defined inhibitory and excitatory cortical neurons undelie the coherency of aversive memory retrieval - an evolutionary pre-requisite for animal survival.
https://t.co/UKESFaGycH