Eunchai Kang

Lecturer @aberdeenuni @kangberglab

[Eunchai Kang @neural_lab]

Excited to share our new paper in Nature Communications!
We mapped how extracellular matrix (matrisome) genes shape human cortical development and how their dysregulation is linked to neurodevelopmental disorders.

https://t.co/0iTnGPZp1D

[University of Aberdeen @aberdeenuni]

Researchers from the University of Aberdeen have uncovered, for the first time, how genes linked to autism and intellectual disability may influence early brain development. https://t.co/Bsnmr3J87a @kangberglab

[Paul Fowler @GrumpybaldProf]

Great new study highlighting the importance of ECM in both normal development and the pathogenesis of NDDs just published by Kang & Berg group
https://t.co/d5J3vrQHYd
Delighted that the SAFeR Study was able to contribute.

[Eunchai Kang @neural_lab]

Excited to share our new paper in Nature Communications!
We mapped how extracellular matrix (matrisome) genes shape human cortical development and how their dysregulation is linked to neurodevelopmental disorders.

https://t.co/0iTnGPZp1D

[Eunchai Kang @neural_lab]

Thanks to the authors Do Hyeon, @drzamankhan @GrumpybaldProf @OliviaSoper19 and Mike Morgan. Thanks for funding from @humane_research who helped make this possible! And @BBSRC @acmedsci @The_MRC @HorizonEU.
@AberdeenNeuro @aberdeenuni

[Eunchai Kang @neural_lab]

Excited to share our new paper in Nature Communications!
We mapped how extracellular matrix (matrisome) genes shape human cortical development and how their dysregulation is linked to neurodevelopmental disorders.

https://t.co/0iTnGPZp1D

[Aberdeen Neuroscience @AberdeenNeuro]

Neuroscientists at the University of Aberdeen have published a new study in Nature Communications. It maps how extracellular matrix (matrisome) genes shape human cortical development and are linked to neurodevelopmental disorders.
Read the paper here: https://t.co/kMFXRXvJ9T

[Eunchai Kang @neural_lab]

Transcriptomic and functional analyses reveal that glucocorticoid signalling enforces NSC quiescence through autophagy-linked programs, limiting hippocampal growth.
@AberdeenNeuro @kangberglab

[Eunchai Kang @neural_lab]

New preprint!
We present a new human iPSC-derived hippocampal organoid model that recapitulates key features of hippocampal development and neurogenesis.
Spearheaded by @OliviaSoper19 https://t.co/fL0ktS5I4n

[Eunchai Kang @neural_lab]

These organoids maintain organized neural stem cell niches, support ongoing neurogenesis, and generate hippocampus-specific neurons.
We used the model to study prenatal glucocorticoid exposure, which reduced NSC proliferation and drove a precocious quiescent-like state.

[KangBerg lab @kangberglab]

Congratulations to @OliviaSoper19 on successfully defending her PhD thesis! 🎓👏 Thanks to @derekgarden and Kat Bowles for serving as external examiners and for their thoughtful input. #PhDDefense #Neuroscience

[Eunchai Kang @neural_lab]

Poster presentation by Do Hyeon at the anatomical society summer meeting in Oxford @anat_soc @aberdeenuni @humane_research

[Asmita Goswami @asmitanatomy99]

Fascinating talk 💡by Dr. Muhammad Assir (@drzamankhan) on how IL-17A disrupts cortical development in a 3D ex vivo MIA model—triggering early folding, increased thickness & neuronal maturation. 🧠📚 #AnatSocSummer25 #AnatSocOxford

[Elena Patera @ArtedelCuerpoH1]

Wonderful presentation by David Berg from @aberdeenuni on how using
human tissue and 3D
organoid modelling helps understand better the neurogenic niche of the developing dentate gyrus and its relevance in neurodevelopmental disorders 👏 #AnatSocSummer25 #AnatSocOxford

[KangBerg lab @kangberglab]

Poster 4 by @SaraValkila , learn about her work on the human ganglionic eminences and how they are affected by maternal inflammation #AnatSocSummer25 @aberdeenuni @anat_soc

[Muhammad Zaman Khan Assir @drzamankhan]

Heartfelt thanks to my PhD supervisor, Dr.
@neural_lab , and to my family, friends, and colleagues who supported me along the way. Here’s to new beginnings—and to making a difference. #Graduation #PhDJourney #LifelongLearning #Science #GrowthMindset #UniversityOfAberdeen

[KangBerg lab @kangberglab]

Sincere thanks to Prof John Mason (external) and Dr Emilie Hollville (internal) for their expert examination and thoughtful discussion. 🧠👏
@AbdnLifeScience @aberdeenuni @AberdeenNeuro

[KangBerg lab @kangberglab]

🎓 Congratulations to Dr Do Hyeon Gim on a brilliant PhD defense! His thesis uncovers cell-type and temporal-specific matrisome expression signatures in human cortical development and neurodevelopmental disorders. Read it here: https://t.co/p9bP5d4BHs

[Muhammad Zaman Khan Assir @drzamankhan]

Including an interesting panel discussion on advantages and limitations of existing iPSC models @neural_lab.
It appears, however, that there are many outstanding questions in the organoid field that require further discussions and consensus in the field.

[Eunchai Kang @neural_lab]

Proud of my first PhD student Muhammad @drzamankhan who passed his viva! Great job! And thanks to Dr Theil and Dr Garden who gave valuable feedback. @AberdeenNeuro @aberdeenuni

[Eunchai Kang @neural_lab]

Check out the first pre-print from our lab. Great work by first author @drzamankhan . And thanks to all the co-authors!

[Muhammad Zaman Khan Assir @drzamankhan]

🚨 New findings! 🚨Maternal inflammation doesn’t just change the cellular makeup of the developing human cortex—it extensively remodels its extracellular matrix.
In our latest work, we dive deep into the effects of IL-17A, key cytokine in maternal inflammation, on developing🧠.🧵