How do antibodies cooperate?
Nice work by @MOUQUETHugo1 and coll.
Broad Sarbecovirus Neutralization by Combined Memory B-cell Antibodies to Ancestral SARS-CoV-2:
https://t.co/Jyr8ZKO3DY
In new study led by Caleb Carr & @khdcrawford, we measure how all mutation to Lassa virus glycoprotein complex (GPC) affect cell entry & antibody escape
Results show how prospective assessment of effects of mutations can inform design of countermeasures
https://t.co/M2LmbTbwKm
Deep Mutational Engineering of broadly-neutralizing and picomolar affinity nanobodies to accommodate SARS-CoV-1 & 2 antigenic polymorphism https://t.co/CYhspHbM8M